Browse our NADPH Oxidase 4 (NOX4) ELISA Kits

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NADPH Oxidase 4 ELISA Kits (NOX4)
On www.antibodies-online.com are 15 NADPH Oxidase 4 (NOX4) ELISA Kits from 6 different suppliers available. Additionally we are shipping NADPH Oxidase 4 Antibodies (178) and NADPH Oxidase 4 Proteins (12) and many more products for this protein. A total of 212 NADPH Oxidase 4 products are currently listed.
Synonyms:
AI648021, KOX, KOX-1, NOX4, RENOX

NADPH Oxidase 4 (NOX4) ELISA Kits by Reactivity

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Top referenced NADPH Oxidase 4 ELISA Kits

  1. Rat (Rattus) NOX4 ELISA Kit for Sandwich ELISA - ABIN431602 : El-Naga: Apocynin protects against ethanol-induced gastric ulcer in rats by attenuating the upregulation of NADPH oxidases 1 and 4. in Chemico-biological interactions 2015 (PubMed)

  2. Mouse (Murine) NOX4 ELISA Kit for Sandwich ELISA - ABIN424309 : Vital, Castro, Ittmann: Oxidative stress promotes benign prostatic hyperplasia. in The Prostate 2016 (PubMed)

More ELISA Kits for NADPH Oxidase 4 Interaction Partners

Human NADPH Oxidase 4 (NOX4) interaction partners

  1. NOX4 knockout cell lines showed reduced cell proliferation with an increase of sub-G1 cell population and the decrease of S/G2 (show STRN3 ELISA Kits)/M population, and resulted in a dramatic decrease in invadopodium formation and the invasive activity. NOX4 deficiency caused a decrease in focal adhesions and cell migration in HeLa cells. The results suggest that NOX4 is required for both efficient proliferation and invasion of HeLa cells.

  2. Thioredoxin (show TXN ELISA Kits) attenuates oxidized low-density lipoprotein induced oxidative stress in human umbilical vein endothelial cells by reducing NOX2 (show CYBB ELISA Kits)-NOX4 activity.

  3. Nox4-derived H2O2 in part activates Nox2 (show CYBB ELISA Kits) to increase mitochondrial ROS (show ROS1 ELISA Kits) via pSer36-p66Shc (show SHC1 ELISA Kits), thereby enhancing VEGFR2 (show KDR ELISA Kits) signaling and angiogenesis in endothelial cells.

  4. TGF-beta1 (show TGFB1 ELISA Kits) increases NADPH oxidase 4 (NOX4) mRNA and protein expression in normal human lung fibroblasts (NHLFs) and causes nuclear export of HDAC4 (show HDAC4 ELISA Kits).

  5. Nox4 should contribute to the pathological processes insubarachnoid hemorrhage(SAH (show ACSM3 ELISA Kits))-induced early brain injury (EBI (show TBL1X ELISA Kits)), and there was not an overlay effect of Nox2 (show CYBB ELISA Kits) inhibition and Nox4 inhibition on preventing SAH (show ACSM3 ELISA Kits)-induced EBI (show TBL1X ELISA Kits).

  6. TGFbeta1 (show TGFB1 ELISA Kits) was found to induce Nox4 mRNA expression and total collagen release by these cells (P < 0.05; n = 4), and both responses are blocked by Smad3 (show SMAD3 ELISA Kits) inhibitor SIS3. Suppressing Nox4 gene transcription with Adv (show AVIL ELISA Kits)-Nox4i completely attenuated TGFbeta1 (show TGFB1 ELISA Kits)-stimulated H2O2 release and collagen production by conjunctival fibroblasts

  7. CD44V6 is part of a positive-feedback loop with TGFbeta1 (show TGFB1 ELISA Kits)/TGFbetaRI signaling that acts to increase NOX4/ROS (show ROS1 ELISA Kits) production, which is required for myofibroblast differentiation, myofibroblast differentiation, myofibroblast extracellular matrix production, myofibroblast invasion, and myofibroblast contractility.

  8. Endoplasmic reticulum stress triggers a localized signaling module on the ER surface involving Nox4-dependent calcium mobilization, which directs local Ras activation through ER-associated, calcium-responsive RasGRF.

  9. PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) signaling only occurs when FLT3 (show FLT3 ELISA Kits)-ITD is expressed at the plasma membrane and is required for the production of NOX-generated ROS (show ROS1 ELISA Kits). ER retention of FLT3 (show FLT3 ELISA Kits)-ITD resulted in NOX4 deglycosylation and p22(phox (show CYBA ELISA Kits)) protein degradation.

  10. NOX4 upregulation confers anoikis resistance.

Cow (Bovine) NADPH Oxidase 4 (NOX4) interaction partners

  1. Peroxide derived from superoxide generated by Nox4 appears to maintain a basal relaxation in bovine pulmonary arteries under normoxic conditions, which is removed under hypoxia leading to hypoxic pulmonary vasoconstriction.

Rabbit NADPH Oxidase 4 (NOX4) interaction partners

  1. proteasome inhibition completely prevented endoplasmic reticulum stress-induced increase in NADPH oxidase (show NOX1 ELISA Kits) activity, as well as increases in Nox4 isoform and protein disulfide isomerase (show P4HB ELISA Kits) mRNA expression

Mouse (Murine) NADPH Oxidase 4 (NOX4) interaction partners

  1. Data suggests that ROS (show ROS1 ELISA Kits) produced during primitive endoderm differentiation is dependent in part on increased NOX1 (show NOX1 ELISA Kits) and NOX4 levels, which is under the control of GATA6 (show GATA6 ELISA Kits). Furthermore, these results suggest that the combined activity of multiple NOX proteins is necessary for the differentiation of F9 cells to primitive endoderm.

  2. Nox4 is upregulated in pericytes in peri (show POSTN ELISA Kits)-infarct areas after acute brain ischemia and may enhance blood-brain barrier breakdown through activation of NFkappaB and matrix metalloproteinase 9 (show MMP9 ELISA Kits), thereby causing enlargement of infarct volume.

  3. Deficiency of NOX4 resulted in reduced expression of carnitine palmitoyltransferase 1A (CPT1A (show CPT1A ELISA Kits)), which is a key mitochondrial enzyme in the fatty acid oxidation (FAO) pathway. The reduced FAO resulted in less activation of the nucleotide-binding domain, leucine-rich-repeat-containing receptor (NLR (show CXCR5 ELISA Kits)), pyrin-domain-containing 3 (NLRP3 (show NLRP3 ELISA Kits)) inflammasome in macrophages.

  4. NOX4- and NOX1 (show NOX1 ELISA Kits)-derived ROS (show ROS1 ELISA Kits) contribute to atherosclerosis in the aortic sinus of diabetic ApoE (show APOE ELISA Kits) knockout mice.

  5. CD44V6 is part of a positive-feedback loop with TGFbeta1 (show TGFB1 ELISA Kits)/TGFbetaRI signaling that acts to increase NOX4/ROS (show ROS1 ELISA Kits) production, which is required for myofibroblast differentiation, myofibroblast differentiation, myofibroblast extracellular matrix production, myofibroblast invasion, and myofibroblast contractility.

  6. Nox4 mitigates cerebral artery structural changes in a murine model of Marfan syndrome.

  7. Data show that pan-NOX-inhibitor APX (show SHROOM1 ELISA Kits)-115 treatment decreased NADPH oxidase (show NOX1 ELISA Kits) (Nox) Nox1 (show NOX1 ELISA Kits), Nox2 (show CYBB ELISA Kits), and Nox4 protein expression in the kidney.

  8. enhancement of mitochondrial bioenergetics as well as the increase in mitochondrial proteins in Nox4-deficient lung fibroblasts is inhibited by silencing of nuclear factor erythroid-derived 2-like 2 (Nrf2 (show NFE2L2 ELISA Kits)), supporting a key role for Nrf2 (show NFE2L2 ELISA Kits) in control of mitochondrial biogenesis

  9. The production of superoxide anion in nockout-Rtp801 (show DDIT4 ELISA Kits) mouse lung fibroblasts (MLF) was lower than that in Rtp801 (show DDIT4 ELISA Kits) Wt cells after cigarette smoke extract treatment, and it was inhibited in Wt MLF by silencing nicotinamide adenine dinucleotide phosphate oxidase (show DUOX1 ELISA Kits)-4 (Nox4) expression with small interfering Nox4 RNA.

  10. These studies provide insight into the roles of Nox4/senescence in endothelial cells barrier responses.

Pig (Porcine) NADPH Oxidase 4 (NOX4) interaction partners

  1. MRTF down-regulation/inhibition suppresses TGFbeta (show TGFB1 ELISA Kits)/contact disruption-provoked Nox4 protein and mRNA expression, Nox4 promoter activation, and reactive oxygen species production.

  2. Nox4 NADPH oxidase (show NOX1 ELISA Kits) mediates oxidative stress and apoptosis caused by TNF-alpha (show TNF ELISA Kits) in cerebral vascular endothelial cells.

  3. Nox4 NADPH oxidase (show NOX1 ELISA Kits)-derived reactive oxygen species also initiate a cell survival mechanism by increasing production of carbon monoxide by constitutive heme oxygenase-2 (show HMOX2 ELISA Kits).

NADPH Oxidase 4 (NOX4) Antigen Profile

Antigen Summary

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with NADPH Oxidase 4 (NOX4)

  • NADPH oxidase 4 (NOX4) Elisa Kit
  • NADPH oxidase 4 (nox4) Elisa Kit
  • NADPH oxidase 4 (PTRG_09562) Elisa Kit
  • NADPH oxidase 4 (Nox4) Elisa Kit
  • AI648021 Elisa Kit
  • KOX Elisa Kit
  • KOX-1 Elisa Kit
  • NOX4 Elisa Kit
  • RENOX Elisa Kit

Protein level used designations for NADPH Oxidase 4 (NOX4) ELISA Kits

NADPH oxidase 4 , predicted NADPH oxidase-4 , kidney oxidase-1 , kidney superoxide-producing NADPH oxidase , renal NAD(P)H-oxidase , KOX-1 , superoxide-generating NADPH oxidase 4 , kox-1

GENE ID SPECIES
419012 Gallus gallus
619226 Ciona intestinalis
705931 Macaca mulatta
735636 Pan troglodytes
6347852 Pyrenophora tritici-repentis Pt-1C-BFP
50507 Homo sapiens
378474 Bos taurus
100034665 Ovis aries
100339697 Oryctolagus cuniculus
50490 Mus musculus
85431 Rattus norvegicus
100523323 Sus scrofa
485144 Canis lupus familiaris
100171782 Pongo abelii
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