Browse our PCK1 (PCK1) ELISA Kits

On www.antibodies-online.com are 26 phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1) ELISA Kits from 8 different suppliers available. Additionally we are shipping PCK1 Antibodies (181) and PCK1 Proteins (9) and many more products for this protein. A total of 232 PCK1 products are currently listed.
Synonyms:
143299_at, AI265463, cb856, cb924, CG10924, CG17725, Dmel\\CG17725, dPEPCK, Dromel_CG17725_FBtr0086701_pepck_mORF, fj93h11, GTP, PCK, Pck-1, PCK1, Pepck, PEPCK-C, PEPCK1, PEPCKC, PHOSPHOENOLPYRUVATE CARBOXYKINASE, phosphoenolpyruvate carboxykinase 1, Ppc1C, PPCK1, RATPEPCK, T28I19.150, T28I19_150, wu:fc51c05, wu:fj93h11, zgc:63869
list all ELISA KIts Gene Name GeneID UniProt
PCK1 5105 P35558
PCK1 362282 P07379
PCK1 18534 Q9Z2V4

PCK1 (PCK1) ELISA Kits by Reactivity

More ELISA Kits for PCK1 Interaction Partners

Arabidopsis thaliana phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1) interaction partners

  1. Arabidopsis uses two gluconeogenic gateways for organic acids to fuel seedling establishment, one is via PCK1, and a second via PPDK.

  2. Malate metabolism is important during dark-induced stomatal closure and that phosphoenolpyruvate carboxykinase (PEPCK) is involved in this process.

Human phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1) interaction partners

  1. Study investigated the molecular basis of such effects focusing on a commonly studied polymorphism in pig Pgc1alpha, which changes a cysteine at position 430 (WT) of the protein to a serine (C430S); found that differential O-GlcNAcylation of Pgc1alpha regulates PCK1 activity and this molecular mechanism could explain at least in part the epistatic interaction between both genes.

  2. Study identified a novel homozygous PCK1 missense mutation causing cytosolic phosphoenolpyruvate carboxykinase deficiency presenting as childhood hypoglycemia.

  3. HBXIP (show HBXIP ELISA Kits) is able to depress the gluconeogenesis in hepatoma cells by suppressing PCK1 to promote hepatocarcinogenesis, involving miR (show MLXIP ELISA Kits)-135a/FOXO1 (show FOXO1 ELISA Kits) axis and PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits)/p-FOXO1 (show FOXO1 ELISA Kits) pathway.

  4. A mutation of PCK1 associated with Smith-Magenis Syndrome, cytosolic PEPCK (show PEPCK ELISA Kits) deficiency and NMDA receptor glutamate (show GRIN1 ELISA Kits) insensitivity.

  5. Insulin (show INS ELISA Kits)-dependent translocation of FOXO1 (show FOXO1 ELISA Kits) regulated transcriptional repression of PCK1 concomitant with the formation of the FOXO1 (show FOXO1 ELISA Kits)-euchromatic histone-lysine N-methyltransferase2 (show DNMT1 ELISA Kits) (EHMT2 (show EHMT2 ELISA Kits)) complex and histone modifications of the PCK1 promoter region

  6. Lipopolysaccharide and monophosphoryl lipid A also up-regulated G6PC (show G6PC ELISA Kits) and PCK1 transcript abundance in a TLR4 (show TLR4 ELISA Kits)-dependent manner.

  7. The PCK1 tag-single nucleotide polymorphisms influenced insulin (show INS ELISA Kits) resistance by interacting with plasma n-3 polyunsaturated fatty acids levels in metabolic syndrome patients.

  8. HCV core protein expression-mediated FOXO1 (show FOXO1 ELISA Kits) activation and the increased PGC-1alpha (show PPARGC1A ELISA Kits) leaded to the elevation of PCK1 at the mRNA level

  9. Acetylation regulates the stability of the gluconeogenic rate-limiting enzyme PEPCK1.

  10. Data show PEPCK-C and CPT-1 (show CPT1A ELISA Kits) mRNAs are more abundant in non-tumoral tissues than in the tumoral counterpart, whereas the opposite occurred for the FAS (show FAS ELISA Kits) gene.

Pig (Porcine) phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1) interaction partners

  1. Study investigated the molecular basis of such effects focusing on a commonly studied polymorphism in pig Pgc1alpha, which changes a cysteine at position 430 (WT) of the protein to a serine (C430S); found that differential O-GlcNAcylation of Pgc1alpha regulates PCK1 activity and this molecular mechanism could explain at least in part the epistatic interaction between both genes.

  2. the renal proximal tubule, may require the remodeling of AUF1 (show HNRNPD ELISA Kits) binding to the elements that mediate the rapid turnover of PEPCK (show PEPCK ELISA Kits) mRNA

Cow (Bovine) phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1) interaction partners

  1. Collectively, the identified 3'-untranslated-region SNP variant highlights the importance of PCK1 in the fecundity of Holstein bulls, and implicates a role for bta-miR (show MYLIP ELISA Kits)-26a in regulating PCK1 abundance.

  2. Expression of cytosolic PEPCK (show PEPCK ELISA Kits) mRNA is transiently increased during early lactation, indicating that enhanced hepatic gluconeogenesis during lactation may be tied to enhanced capacity for cytosolic formation of phosphoenolpyruvate.

Mouse (Murine) phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1) interaction partners

  1. Data (including data from studies in knockout mice) suggest that Pck1 in liver plays role in glucose homeostasis; here, Pck1 deficiency (in knockout mice) can be successfully treated by re-expression of Pck1 in liver, thus partially rescuing pups from fatal neonatal hypoglycemia. Pck1 appears to play roles in metabolism in lung and skeletal muscle.

  2. Silencing PCK1 or inhibiting its enzymatic activity slows the growth of tumor-repopulating cells in vitro and impedes tumorigenesis in vivo.

  3. PEPCK-M expression partially rescued defects in lipid metabolism, gluconeogenesis and TCA cycle function impaired by PEPCK-C deletion, while approximately 10% re-expression of PEPCK-C normalized most parameters.

  4. FAT/CD36 (show CD36 ELISA Kits) regulates PEPCK (show PEPCK ELISA Kits) in adipose tissue and that this could be secondary to reductions in lipolysis.

  5. PCB (show PC ELISA Kits) 126 blunted the forskolin-stimulated increase in phosphoenolpyruvate carboxykinase (PEPCK (show PEPCK ELISA Kits)) mRNA levels.

  6. the role of IL-6 (show IL6 ELISA Kits) signalling in adipose tissue during exercise

  7. there are multiple cytokine pathways by which inflammation inhibits PEPCK (show PEPCK ELISA Kits) expression in adipose tissue which could contribute to the increased mobilization of fatty acids during inflammation

  8. Glucagon (show GCG ELISA Kits) can also regulate Pck1 in the intestine, but not in the kidneys.

  9. Pck1 plays an important role in both the mammary gland adipocytes and epithelial cells during lactation

  10. Results suggest that HDAC3 (show HDAC3 ELISA Kits) mediates NF-kappaB (show NFKB1 ELISA Kits) activity to repress Pepck (show PEPCK ELISA Kits) transcription.

Maize/Corn (Zea mays) phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1) interaction partners

  1. The regulatory properties of maize phosphoenolpyruvate carboxylase were significantly altered by site-directed mutagenesis of residues 226 through 232.

PCK1 Antigen Profile

Antigen Summary

This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.

Alternative names and synonyms associated with PCK1

  • phosphoenolpyruvate carboxykinase [ATP] (PCK1) Elisa Kit
  • Phosphoenolpyruvate carboxykinase (Pepck) Elisa Kit
  • phosphoenolpyruvate carboxykinase 1 (soluble) (pck1) Elisa Kit
  • phosphoenolpyruvate carboxykinase 1 (soluble) (PCK1) Elisa Kit
  • Phosphoenolpyruvate carboxykinase, cytosolic (ppckc) Elisa Kit
  • phosphoenolpyruvate carboxykinase 1 (soluble) (LOC100224850) Elisa Kit
  • phosphoenolpyruvate carboxykinase 1 (soluble) (Pck1) Elisa Kit
  • phosphoenolpyruvate carboxykinase 1, cytosolic (Pck1) Elisa Kit
  • phosphoenolpyruvate carboxylase7 (pep7) Elisa Kit
  • 143299_at Elisa Kit
  • AI265463 Elisa Kit
  • cb856 Elisa Kit
  • cb924 Elisa Kit
  • CG10924 Elisa Kit
  • CG17725 Elisa Kit
  • Dmel\\CG17725 Elisa Kit
  • dPEPCK Elisa Kit
  • Dromel_CG17725_FBtr0086701_pepck_mORF Elisa Kit
  • fj93h11 Elisa Kit
  • GTP Elisa Kit
  • PCK Elisa Kit
  • Pck-1 Elisa Kit
  • PCK1 Elisa Kit
  • Pepck Elisa Kit
  • PEPCK-C Elisa Kit
  • PEPCK1 Elisa Kit
  • PEPCKC Elisa Kit
  • PHOSPHOENOLPYRUVATE CARBOXYKINASE Elisa Kit
  • phosphoenolpyruvate carboxykinase 1 Elisa Kit
  • Ppc1C Elisa Kit
  • PPCK1 Elisa Kit
  • RATPEPCK Elisa Kit
  • T28I19.150 Elisa Kit
  • T28I19_150 Elisa Kit
  • wu:fc51c05 Elisa Kit
  • wu:fj93h11 Elisa Kit
  • zgc:63869 Elisa Kit

Protein level used designations for PCK1

CG17725-PA , CG17725-PB , Pepck-PA , Pepck-PB , Phosphoenolpyruvate-carboxykinase , phosphoenol pyruvate carboxykinase , phosphoenolpyruvate carboxy kinase , phosphoenolpyruvate carboxykinase , phosphoenolpyruvate carboxykinase, cytosolic , PEPCK , phosphoenolpyruvate carboxykinase 1 (soluble) , Phosphoenolpyruvate carboxykinase, cytosolic , Phosphoenolpyruvate carboxykinase 1 (soluble)-like , PEPCK-C , cytosolic phosphoenolpyruvate carboxykinase , phosphoenolpyruvate carboxykinase, cytosolic [GTP] , phosphoenolpyruvate carboxylase , PEP carboxykinase , phosphopyruvate carboxylase , phosphoenolpyruvate carboxykinase 1 variant 1 , phosphoenolpyruvate carboxykinase 1 variant 2 , phosphoenolpyruvate carboxykinase 1 variant 3 , phosphoenolpyruvate carboxykinase 1 variant 4 , phosphoenolpyruvate carboxykinase 1 variant 5 , phosphoenolpyruvate carboxykinase (GTP) , phosphoenolpyruvate carboxykinase 1, cytosolic , phosphoenolpyruvate carboxykinase, cytosolic (GTP) , gluconeogenic enzyme , CL1793_1 , CL1793_1_ov , Ppc1 , pMR15 , pep*-pepcZm2A , pep8 , synonymous gene name: Pep2 in maize linkage map

GENE ID SPECIES
829943 Arabidopsis thaliana
37131 Drosophila melanogaster
378727 Danio rerio
379637 Xenopus laevis
696207 Macaca mulatta
100195420 Salmo salar
100224850 Taeniopygia guttata
100355682 Oryctolagus cuniculus
100634531 Amphimedon queenslandica
396458 Gallus gallus
5105 Homo sapiens
100144531 Sus scrofa
282855 Bos taurus
362282 Rattus norvegicus
403560 Canis lupus familiaris
18534 Mus musculus
542479 Zea mays
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