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anti-Human SATB1 Antibodies:
anti-Rat (Rattus) SATB1 Antibodies:
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Human Monoclonal SATB1 Primary Antibody for IF, WB - ABIN968403
de Belle, Cai, Kohwi-Shigematsu: The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1) in vivo in Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops. in The Journal of cell biology 1998
Show all 6 references for ABIN968403
Human Polyclonal SATB1 Primary Antibody for EIA, IHC (p) - ABIN500672
Cai, Han, Kohwi-Shigematsu: Tissue-specific nuclear architecture and gene expression regulated by SATB1. in Nature genetics 2003
Show all 4 references for ABIN500672
Human Polyclonal SATB1 Primary Antibody for EIA, IHC (p) - ABIN500670
Dickinson, Kohwi-Shigematsu: Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential. in Molecular and cellular biology 1995
Show all 3 references for ABIN500670
Chicken Polyclonal SATB1 Primary Antibody for WB - ABIN2777889
Green, Roeder: Definition of a novel promoter for the major adenovirus-associated virus mRNA. in Cell 1981
Show all 2 references for ABIN2777889
Human Polyclonal SATB1 Primary Antibody for IF (p), IHC (p) - ABIN745613
Han, Xia, Qin, Han, Wu: Phosphorylated SATB1 is associated with the progression and prognosis of glioma. in Cell death & disease 2013
Results suggested that high expression of SATB1 is significantly correlated with poor differentiation of CRC (show CALR Antibodies). SATB1 might promote the epithelial-mesenchymal transition by increasing the aberrant expression of beta-catenin (show CTNNB1 Antibodies).
Logistic regression revealed that four variants in NR3C1 (show NR3C1 Antibodies) and SATB1 were significantly associated with lung cancer risk after false discovery rate (FDR) correction [For NR3C1 (show NR3C1 Antibodies), rs9324921: odds ratio (OR)=1.23, P for FDR=0.029; rs12521436: OR=0.85, P for FDR=0.040; rs4912913: OR=1.17, P for FDR=0.040; For SATB1, rs6808523: OR=1.33, P for FDR=0.040].
modulation of epithelial-mesenchymal transition by SATB1 may contribute to prostate cancer metastasis.
Tumor-driven, unremitting expression of Satb1 in activated Zbtb46 (show ZNF340 Antibodies)+ inflammatory dendritic cells that infiltrate ovarian tumors results in an immunosuppressive phenotype characterized by increased secretion of tumor-promotin (show LGALS1 Antibodies)g Galecti (show IL6 Antibodies)n-1 and IL-6.
High expression of SATB1 is associated with colorectal cancer.
radiation decreases SATB1 expression and sensitizes cancer cells to confer clinical benefit of patients, suggesting that SATB1 is predictive of response to preoperative RT and clinical outcome in rectal cancer.
Findings indicate that high Ki67 (show MKI67 Antibodies) antigen/ SATB1 protein ratio was an independent predictor of worse overall survival (OS), while Ki67 (show MKI67 Antibodies) and SATB1 did not reach statistical significance as single predictors.
SATB1 reprograms the expression of tumor growth- and metastasis-associated genes to promote tumorigenesis and functionally overlaps with Wnt (show WNT2 Antibodies) signaling critical for colorectal cancer tumorigenesis.
SATB1 as a Dual Regulator of Anti-Apoptotic BCL2 (show BCL2 Antibodies) and Pro-Apoptotic NOXA (show PMAIP1 Antibodies) Genes
SATB1 protein expression showed an increasing trend in advancing stages of breast cancer development.
Tumor-driven, unremitting expression of Satb1 in activated Zbtb46 (show ZNF340 Antibodies)+ inflammatory DCs that infiltrate ovarian tumors results in an immunosuppressive phenotype characterized by increased secretion of tumor-promoting Galectin-1 (show LGALS1 Antibodies) and IL-6 (show IL6 Antibodies).
These results suggest that SATB1 plays an essential role in establishment of immune tolerance.
Data show that RNA binding protein HuD and special adenine-thymine (AT)-rich DNA-binding protein 1 (SATB1) form a positive regulatory loop that enhances NeuroD1 protein transcription and subsequent neuronal differentiation.
Fluorosed mouse ameloblasts have increased SATB1 retention and Galphaq (show GNAQ Antibodies) activity.
The results indicated that the expression of SATB1 in both mRNA and protein levels was significantly decreased after cells transferred with siRNA sequence for 48 h, the proliferation of MF9 cells was significantly inhibited.
SATB1 binds to the ASE (show ARSE Antibodies) and Rag promoters, facilitating inclusion of Rag2 (show RAG2 Antibodies) in the chromatin hub and the loading of RNA polymerase II to both the Rag1 (show RAG1 Antibodies) and Rag2 (show RAG2 Antibodies) promoters.
SATB1 is indispensable for lymphocyte differentiation and stem cell development. (Review)
The ubiquitin-like domain-CUT repeat-like tandem of SATB1 are required for DNA binding.
Satb1 is a regulator that promotes hematopoietic stem cells quiescence and represses lineage commitment.
SATB1 as a critical regulator of interneuron maturation and terminal differentiation in the mammalian cortex.
This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene.
SATB homeobox 1
, special AT-rich sequence binding protein 1
, AT-rich binding protein-1
, DNA-binding protein SATB1-like
, DNA-binding protein SATB1
, special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA)
, special AT-rich sequence-binding protein 1