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anti-Human SATB1 Antibodies:
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Human Monoclonal SATB1 Primary Antibody for IF, WB - ABIN968403
de Belle, Cai, Kohwi-Shigematsu: The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1) in vivo in Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops. in The Journal of cell biology 1998
Show all 6 Pubmed References
Human Polyclonal SATB1 Primary Antibody for IHC, ELISA - ABIN1003120
Dickinson, Kohwi-Shigematsu: Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential. in Molecular and cellular biology 1995
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Human Polyclonal SATB1 Primary Antibody for ELISA, WB - ABIN1003121
Szemes, Gyorgy, Paweletz, Dobi, Agoston: Isolation and characterization of SATB2, a novel AT-rich DNA binding protein expressed in development- and cell-specific manner in the rat brain. in Neurochemical research 2006
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Human Polyclonal SATB1 Primary Antibody for ELISA, IHC - ABIN4352120
Tan, Sun, Song, Chen, Krontiris, Durrin: SUMO conjugation to the matrix attachment region-binding protein, special AT-rich sequence-binding protein-1 (SATB1), targets SATB1 to promyelocytic nuclear bodies where it undergoes caspase cleavage. in The Journal of biological chemistry 2008
Guinea Pig Polyclonal SATB1 Primary Antibody for WB - ABIN2777889
Green, Roeder: Definition of a novel promoter for the major adenovirus-associated virus mRNA. in Cell 1981
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Guinea Pig Polyclonal SATB1 Primary Antibody for WB - ABIN2780457
Pavan Kumar, Purbey, Sinha, Notani, Limaye, Jayani, Galande: Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. in Molecular cell 2006
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Human Polyclonal SATB1 Primary Antibody for IF (p), IHC (p) - ABIN745613
Han, Xia, Qin, Han, Wu: Phosphorylated SATB1 is associated with the progression and prognosis of glioma. in Cell death & disease 2013
These findings suggest SATB1 may play an important role in OSCC invasiveness and metastasis.
This paper provides evidence that SATB1 plays an oncogenic role in esophageal cancer by up-regulation of FN1 (show FN1 Antibodies) and PDGFRB (show PDGFRB Antibodies).
combination of the sequence-specific and nonspecific DNA-binding modes of SATB1 should be advantageous in a search for target loci during transcriptional regulation
revealed more than 170 NFAT (show NFATC1 Antibodies)-associated proteins, half of which are involved in transcriptional regulation. Among them are many hitherto unknown interaction partners of NFATc1 (show NFATC1 Antibodies) and NFATc2 (show NFAT1 Antibodies) in T cells, such as Raptor (show RPTOR Antibodies), CHEK1 (show CHEK1 Antibodies), CREB1 (show CREB1 Antibodies), RUNX1 (show RUNX1 Antibodies), SATB1, Ikaros (show IKZF1 Antibodies), and Helios (show ZNFN1A2 Antibodies).
SATB1 interacts directly with OGG1 (show OGG1 Antibodies), increases its binding to 8-oxoG-containing DNA, promotes Schiff base formation, and stimulates its glycosylase and apyrimidinic/apurinic lyase enzymatic activities.
High SATB1 expression in was detected in 48.3% of esophageal squamous cell carcinoma and 7.8% of normal esophagus tissues.
Silencing of special AT-rich sequence binding protein 1 inhibited the proliferation of KYSE450 and EC9706 cells which have a relatively high level of special AT-rich sequence binding protein 1, and the ability of migration and invasion of KYSE450 and EC9706 cells was distinctly suppressed.
Results suggest that SATB1 is activated to bind to chromatin at S/MARs (show MARS Antibodies) after exposure to Abeta (show APP Antibodies) 1-42, resulting in alternative utilization and movement of 82-kDa ChAT to these regions demonstrating that both proteins play critical roles in the response of neural cells to acute Abeta (show APP Antibodies)-exposure.
Our results highlight the significance of SATB1 in intrahepatic cholangiocarcinoma
SATB1 expression was decreased in ATL cells compared with normal controls. Knockdown of SATB1 expression significantly enhanced invasion of Jurkat cell in vitro. SATB1 knockdown enhanced beta-catenin (show CTNNB1 Antibodies) nuclear accumulation and transcriptional activity and thus may increase the invasiveness of Jurkat cells through the activation of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway in vitro.
these results identify a role for Satb1 in the lineage choice between pluripotency and differentiation and further our understanding of early embryonic lineage segregation.
This study demonstrating that Satb1-dependent Cntn5 (show CNTN5 Antibodies) expression in ON-OFF direction-selective ganglion cells leads to branch-specific homophilic interactions with interneurons.
we show that special AT-rich binding protein 1 (SATB1), a T lineage-enriched chromatin organizer and regulator, is induced in response to TCR signaling during early thymocyte development
this study shows that Satb1-dependent Treg cell-specific super-enhancers activation is crucial for Treg cell lineage specification in the thymus
Tumor-driven, unremitting expression of Satb1 in activated Zbtb46 (show ZNF340 Antibodies)+ inflammatory DCs that infiltrate ovarian tumors results in an immunosuppressive phenotype characterized by increased secretion of tumor-promoting Galectin-1 (show LGALS1 Antibodies) and IL-6 (show IL6 Antibodies).
These results suggest that SATB1 plays an essential role in establishment of immune tolerance.
Data show that RNA binding protein HuD and special adenine-thymine (AT)-rich DNA-binding protein 1 (SATB1) form a positive regulatory loop that enhances NeuroD1 protein transcription and subsequent neuronal differentiation.
Fluorosed mouse ameloblasts have increased SATB1 retention and Galphaq (show GNAQ Antibodies) activity.
The results indicated that the expression of SATB1 in both mRNA and protein levels was significantly decreased after cells transferred with siRNA sequence for 48 h, the proliferation of MF9 cells was significantly inhibited.
SATB1 binds to the ASE (show ARSE Antibodies) and Rag promoters, facilitating inclusion of Rag2 (show RAG2 Antibodies) in the chromatin hub and the loading of RNA polymerase II to both the Rag1 (show RAG1 Antibodies) and Rag2 (show RAG2 Antibodies) promoters.
This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene.
SATB homeobox 1
, special AT-rich sequence binding protein 1
, AT-rich binding protein-1
, DNA-binding protein SATB1-like
, DNA-binding protein SATB1
, special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA)
, special AT-rich sequence-binding protein 1