Browse our Cadherin 4 Proteins (CDH4)

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Cadherin 4 Proteins (CDH4)
On are 8 Cadherin 4 (CDH4) Proteins from 3 different suppliers available. Additionally we are shipping Cadherin 4 Antibodies (88) and Cadherin 4 Kits (4) and many more products for this protein. A total of 106 Cadherin 4 products are currently listed.
AW120700, CAD4, cadherin-4, Cdh4l, R-Cadh, R-cadherin, RCAD, zgc:136316
list all proteins Gene Name GeneID UniProt
CDH4 12561 P39038
Rat CDH4 CDH4 114588  
CDH4 1002 P55283

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Cadherin 4 Proteins (CDH4) by Origin

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Top referenced Cadherin 4 Proteins

  1. Human Cadherin 4 Protein expressed in Human Cells - ABIN2002396 : Fagman, Grände, Edsbagge, Semb, Nilsson: Expression of classical cadherins in thyroid development: maintenance of an epithelial phenotype throughout organogenesis. in Endocrinology 2003 (PubMed)
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More Proteins for Cadherin 4 Interaction Partners

Mouse (Murine) Cadherin 4 (CDH4) interaction partners

  1. cadherin 2 (CDH2 (show CDH2 Proteins)) and CDH4 cooperate to regulate radial migration in mouse brain via the protein tyrosine phosphatase 1B (PTP1B (show PTPN1 Proteins)) and alpha- and beta-catenins.

  2. Pioneer axon outgrowth was rescued in vivo by selective replacement of R-cadherin by electroporation into cultured Pax6 (show PAX6 Proteins) mutant embryos

  3. analysis of subpopulations of HSCs for expression of cell surface adhesion molecules found that R-cadherin was preferentially expressed by HSCs functionally targeting neovascularization in the developing retina

  4. Killer cell lectin-like receptor G1 (KLRG1 (show KLRG1 Proteins)) ligation by R-cadherin may regulate the cytotoxicity of killer cells to prevent damage to tissues expressing cadherins.

  5. suggest that R-cad is an adhesion molecule (show NCAM1 Proteins) of the mammary epithelium, which acts as a critical regulator of the normal phenotype

Zebrafish Cadherin 4 (CDH4) interaction partners

  1. Both Cdh2 (show CDH2 Proteins) and Cdh4 immunoreactivities were specifically up-regulated in regenerating retina and/or the optic pathway and both may be important for regeneration of injured retinal ganglion cell axons

  2. analyzed expression patterns of three zebrafish classical (type I) cadherins (cadherin-1 (show CDH1 Proteins), -2, and -4) in the embryonic zebrafish cranial ganglia and lateral line system

  3. Cadherin-4 was not detected in the embryonic Zebrafish cerebellum, but it was expressed in the Purkinje cells of the larval and adult cerebellum.

  4. Cdh4 is necessary for neural retina survival and differentiation

  5. Results indicate that Cdh4 plays a role in the normal formation of the zebrafish lateral line system and a subset of the cranial ganglia.

Human Cadherin 4 (CDH4) interaction partners

  1. Low expression of CDH4 is associated with lung cancer.

  2. Further knockdown R-cadherin in linc-cdh4-2 stably overexpressed cells, could significantly upregulate the protein levels of RAC1 and improve the cell migration and invasion abilities. Taken together, the novel linc-cdh4-2 may negatively regulate the motility of the HCC cells through targeting R-cadherin-RAC1 signaling pathway.

  3. Data show that low expression of R-cadherin is associated with the poor prognosis in gastric cancer.

  4. P-cadherin expression correlated with tumor progression and could be an independent predictor for bladder cancer survival.

  5. R-cadherin adherens junction formation facilitates a mesenchymal to epithelial-like transition in MDA-MB-231 cells.

  6. Findings identify an important role of CHD4 (show CHD4 Proteins) in controlling homologous recombination repair to maintain genome stability and establish the potential therapeutic implications of targeting CHD4 (show CHD4 Proteins) deficiency in tumors.

  7. a novel putative tumor suppressor gene that can be frequently and tumor-specifically inactivated by its promoter methylation in nasopharyngeal carcinoma

  8. R-cadherin induces cell motility when expressed in epithelial cells, and this increased motility is dependent upon Rho GTPase (show RACGAP1 Proteins) activity.

  9. CDH4 may act as a tumor suppressor gene in human gastrointestinal tumors and can potentially be used as an early diagnostic marker for gastrointestinal tumorigenesis

  10. the degradation of E-cadherin (show CDH1 Proteins) in response to expression of R-cadherin is due to competition for p120(ctn (show CTNND1 Proteins))

Caenorhabditis elegans (C. elegans) Cadherin 4 (CDH4) interaction partners

  1. The fat-like cadherin CDH-4 acts cell-non-autonomously in anterior-posterior neuroblast migration.

  2. CDH-4 functions to ensure that proper cell contacts are made and maintained during development.

Cadherin 4 (CDH4) Protein Profile

Protein Summary

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Cadherin 4 (CDH4)

  • cadherin 4, type 1, R-cadherin (retinal) (cdh4)
  • cadherin 4 (Cdh4)
  • cadherin 4, retinal (cdh4)
  • cadherin 4, type 1, R-cadherin (retinal) (CDH4)
  • Protein CDH-4 (cdh-4)
  • AW120700 protein
  • CAD4 protein
  • cadherin-4 protein
  • Cdh4l protein
  • R-Cadh protein
  • R-cadherin protein
  • RCAD protein
  • zgc:136316 protein

Protein level used designations for Cadherin 4 Proteins (CDH4)

cadherin 4, type 1, R-cadherin (retinal) , R-CAD , cadherin-4 , retina cadherin , retinal cadherin , R-cadherin , cadherin 4 type 1 R-cadherin (retinal) , cadherin 4, type 1, preproprotein

100144729 Xenopus (Silurana) tropicalis
12561 Mus musculus
114588 Rattus norvegicus
30297 Danio rerio
1002 Homo sapiens
419222 Gallus gallus
175590 Caenorhabditis elegans
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