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anti-Human Claudin 1 Antibodies:
anti-Mouse (Murine) Claudin 1 Antibodies:
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Human Monoclonal Claudin 1 Primary Antibody for IHC (p), IP - ABIN563931
Mee, Grove, Harris, Hu, Balfe, McKeating: Effect of cell polarization on hepatitis C virus entry. in Journal of virology 2007
Show all 16 Pubmed References
Human Polyclonal Claudin 1 Primary Antibody for WB - ABIN2801934
Halford, Spencer, Greenwood, Winton, Hunt, Adamson: Assignment of claudin-1 (CLDN1) to human chromosome 3q28-->q29 with somatic cell hybrids. in Cytogenetics and cell genetics 2000
Show all 4 Pubmed References
Human Polyclonal Claudin 1 Primary Antibody for ELISA, ICC - ABIN4298947
Dietze, Shihan, Stammler, Konrad, Scheiner-Bobis: Cardiotonic steroid ouabain stimulates expression of blood-testis barrier proteins claudin-1 and -11 and formation of tight junctions in Sertoli cells. in Molecular and cellular endocrinology 2015
Show all 2 Pubmed References
Human Monoclonal Claudin 1 Primary Antibody for CyTOF, FACS - ABIN4898991
Farquhar, Hu, Harris, Davis, Brimacombe, Fletcher, Baumert, Rappoport, Balfe, McKeating: Hepatitis C virus induces CD81 and claudin-1 endocytosis. in Journal of virology 2012
Show all 2 Pubmed References
Human Polyclonal Claudin 1 Primary Antibody for IF (p), IHC (p) - ABIN686407
Wang, Chen, Liang, Yan, Lin, Liu, Luo, Huang, Li, Liu, Tang: Notch inhibition promotes fetal liver stem/progenitor cells differentiation into hepatocytes via the inhibition of HNF-1?. in Cell and tissue research 2014
Cow (Bovine) Polyclonal Claudin 1 Primary Antibody for IHC, WB - ABIN2778045
Coyne, Gambling, Boucher, Carson, Johnson: Role of claudin interactions in airway tight junctional permeability. in American journal of physiology. Lung cellular and molecular physiology 2003
Human Monoclonal Claudin 1 Primary Antibody for FACS - ABIN4895295
Giugliano, Petroff, Warren, Jasti, Linscheid, Ward, Kramer, Dobrinskikh, Sheiko, Gale, Golden-Mason, Winn, Rosen: Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. in Journal of immunology (Baltimore, Md. : 1950) 2015
Tumor necrosis factor-alpha (show TNF Antibodies) increases claudin-1, 4, and 7 expression in renal tubular cells, altering permeability and transepithelial electrical resistance.
Cyclosporine A/sirolimus alter claudin-1 expression in renal proximal tubular cells via ERK1/2 (show MAPK1/3 Antibodies) signaling pathway to alter barrier function.
association of genetic polymorphisms of claudin-1 (show CLDN7 Antibodies) with small vessel vascular dementia
Glutamine (show GFPT1 Antibodies) increased claudin-1 (show CLDN7 Antibodies) expression in the colonic mucosa of patients with irritable bowel syndrome.
CLDN-1 promoted the migration and EMT (show ITK Antibodies) through the Notch (show NOTCH1 Antibodies) signaling pathway.
In human lung tissue, Claudin-1 (show CLDN7 Antibodies) is higher in RBFOX3 (show RBFOX3 Antibodies)-positive cells than in RBFOX3 (show RBFOX3 Antibodies)-negative cells. Immunostaining and mRNA quantification revealed that protein levels, but not mRNA levels, of Claudin-1 (show CLDN7 Antibodies) are increased by RBFOX3 (show RBFOX3 Antibodies).
Data show that miR-30a could bind to the 3'-untranslted region of Slug mRNA and increased expression of claudins, a family of tight junction transmembrane proteins.
These findings indicate a previously unrecognized mechanism that miR (show MLXIP Antibodies)-142-5p, targeting CLDN1, plays an important role in Hashimoto's thyroiditis pathogenesis.
Here, the authors identified an interaction between claudin-1 (show CLDN7 Antibodies) and Sec24C (show SEC24C Antibodies), a cargo-sorting component of the coat protein (show GOLPH3 Antibodies) complex II (COPII) vesicular transport system.
Aberrant expression of the tight junction molecules claudin-1 (show CLDN7 Antibodies) and zonula occludens-1 (show TJP1 Antibodies) mediates cell growth and invasion in oral squamous cell carcinoma cells.
Increased expression of intestinal epithelial claudin-1 (show CLDN7 Antibodies) with downregulation of claudin-3 (show CLDN3 Antibodies) has been observed in intestinal inflammatory disorders.
Studies indicate claudin 1 (CLDN-1) as a target for improving epidermal drug absorption and preventing HCV infection and of claudin 4 (CLDN-4 (show CLDN4 Antibodies)) as a target for anticancer therapeutics.
Taken together, these results demonstrate that BTZ (show CASC3 Antibodies)-induced claudin 1 expression may be a valuable therapeutic approach for AD.
Results suggest that TLR4 (show TLR4 Antibodies)-dependent claudin-1 internalization and secondary anion secretion contribute to irinotecan-induced diarrhea.
The data suggested that miR (show MLXIP Antibodies)-29a may regulate tumor growth and migration by targeting CLDN1.
Data show that the spatiotemporal expression of claudin-1 is dysregulated in homeobox (show PRRX1 Antibodies) (Msx) genes Msx1d/d/Msx2d/d uteri.
Cldn-1 is a positive regulator of osteoblast proliferation and differentiation.
We further demonstrate that KRT76 interacts with CLDN1 and propose that this interaction is necessary to correctly position CLDN1 in tight junctions.
MIR29 targets and reduces expression of CLDN1 and NKRF (show NKRF Antibodies) to increase intestinal permeability in inflammatory bowel disease.
Occludin (show OCLN Antibodies) and Claudin-1 expressions in the large intestine are under the circadian control, which is associated with temporal regulation of colonic permeability and also susceptibility to colitis.
regulates intestinal epithelial homeostasis via regulation of Notch (show NOTCH1 Antibodies)-signalling
Downregulation of Sirt1 (show SIRT1 Antibodies) and upregulation of the tight junction protein Claudin-1 by SIRT1 (show SIRT1 Antibodies)-mediated epigenetic regulation in podocytes contributed to albuminuria.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
, claudin 19
, claudin 1
, senescence-associated epithelial membrane protein 1
, tight junction protein