Browse our anti-Claudin 12 (CLDN12) Antibodies

Full name:
anti-Claudin 12 Antibodies (CLDN12)
On www.antibodies-online.com are 62 Claudin 12 (CLDN12) Antibodies from 11 different suppliers available. Additionally we are shipping Claudin 12 Kits (12) and Claudin 12 Proteins (3) and many more products for this protein. A total of 78 Claudin 12 products are currently listed.
Synonyms:
claudin-12, CLDN12, DKFZp469F1620, RGD1561053, wu:fc27c11, wu:fc37h01, zgc:86588
list all antibodies Gene Name GeneID UniProt
CLDN12 9069 P56749
CLDN12 64945 Q9ET43
CLDN12 500000  

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Top referenced anti-Claudin 12 Antibodies

  1. Human Polyclonal CLDN12 Primary Antibody for IF (p), IHC (p) - ABIN2173111 : Sadowska, Ahmedli, Chen, Stonestreet: Ontogeny of tight junction protein expression in the ovine cerebral cortex during development. in Neuroscience 2015 (PubMed)

More Antibodies against Claudin 12 Interaction Partners

Human Claudin 12 (CLDN12) interaction partners

  1. CLDN 12 expression could be clinically useful for predicting the survival of the estrogen receptor (ER (show ESR1 Antibodies))-negative subgroup of patients with breast cancer.

  2. Knockdown of claudin-3 (show CLDN3 Antibodies), claudin-4 (show CLDN4 Antibodies), and claudin-12, but not claudin-1 (show CLDN7 Antibodies), increased breast cancer MCF-7 cell migration with maximal effects observed in claudin-12 siRNA-transfected cells.

  3. These findings strongly suggest that claudin-2 (show CLDN2 Antibodies)- and/or claudin-12-based tight junctions form paracellular Ca(2 (show CA2 Antibodies)+) channels in intestinal epithelia, and they highlight a novel mechanism behind vitamin D-dependent calcium homeostasis.

Mouse (Murine) Claudin 12 (CLDN12) interaction partners

  1. Claudin-12 is expressed at the variety of epithelial tissues in inner ear including Organ of Corti, stria vascularis, Reissner's membrane, spiral limbus, vestibular sensory epithelia, and dark cell area.

  2. 1,25(OH)2D3 downregulates cadherin-17 and upregulates claudin-2 (show CLDN2 Antibodies) and claudin-12 in the intestine, suggesting that 1,25(OH)2D3, by regulating these epithelial cell junction proteins, can route calcium through the paracellular path

  3. These findings strongly suggest that claudin-2 (show CLDN2 Antibodies)- and/or claudin-12-based tight junctions form paracellular Ca(2 (show CA2 Antibodies)+) channels in intestinal epithelia, and they highlight a novel mechanism behind vitamin D-dependent calcium homeostasis.

Claudin 12 (CLDN12) Antigen Profile

Antigen Summary

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.

Alternative names and synonyms associated with Claudin 12 (CLDN12)

  • claudin 12 (cldn12) antibody
  • claudin 12 (CLDN12) antibody
  • claudin 12 (CpipJ_CPIJ011954) antibody
  • claudin-12-like (LOC100391361) antibody
  • claudin 12 (Cldn12) antibody
  • claudin-12 antibody
  • CLDN12 antibody
  • DKFZp469F1620 antibody
  • RGD1561053 antibody
  • wu:fc27c11 antibody
  • wu:fc37h01 antibody
  • zgc:86588 antibody

Protein level used designations for anti-Claudin 12 (CLDN12) Antibodies

claudin-12 , claudin 12 , claudin-12-like

GENE ID SPECIES
549605 Xenopus (Silurana) tropicalis
100174503 Pongo abelii
81593 Danio rerio
463521 Pan troglodytes
496360 Xenopus laevis
608397 Canis lupus familiaris
704058 Macaca mulatta
771872 Gallus gallus
6044554 Culex quinquefasciatus
100060361 Equus caballus
100137459 Papio anubis
100294674 Sus scrofa
100328633 Oryctolagus cuniculus
100391361 Callithrix jacchus
9069 Homo sapiens
64945 Mus musculus
500000 Rattus norvegicus
538709 Bos taurus
101108741 Ovis aries
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