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Browse our anti-Claudin 18 (CLDN18) Antibodies

Full name:
anti-Claudin 18 Antibodies (CLDN18)
On are 59 Claudin 18 (CLDN18) Antibodies from 14 different suppliers available. Additionally we are shipping Claudin 18 Kits (25) and Claudin 18 Proteins (4) and many more products for this protein. A total of 93 Claudin 18 products are currently listed.
claudin-18, CLDN18, SFTA5, SFTPJ
list all antibodies Gene Name GeneID UniProt
CLDN18 51208 P56856
CLDN18 56492 P56857
CLDN18 315953  

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Top referenced anti-Claudin 18 Antibodies

  1. Human Polyclonal CLDN18 Primary Antibody for EIA, FACS - ABIN951546 : Sahin, Koslowski, Dhaene, Usener, Brandenburg, Seitz, Huber, Türeci: Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Show all 2 references for ABIN951546

  2. Human Polyclonal CLDN18 Primary Antibody for IHC, IHC (p) - ABIN4892664 : Jun, Kim, Jung, Choi, Chin: Expression of claudin-7 and loss of claudin-18 correlate with poor prognosis in gastric cancer. in International journal of surgery (London, England) 2014 (PubMed)
    Show all 2 references for ABIN4892664

  3. Cow (Bovine) Polyclonal CLDN18 Primary Antibody for WB - ABIN2776807 : Karanjawala, Illei, Ashfaq, Infante, Murphy, Pandey, Schulick, Winter, Sharma, Maitra, Goggins, Hruban: New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8. in The American journal of surgical pathology 2008 (PubMed)

  4. Cow (Bovine) Polyclonal CLDN18 Primary Antibody for WB - ABIN2776808 : Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. in Mammalian genome : official journal of the International Mammalian Genome Society 2005 (PubMed)

More Antibodies against Claudin 18 Interaction Partners

Human Claudin 18 (CLDN18) interaction partners

  1. suggest that the reduction of CLDN5 (show CLDN5 Antibodies), 7, and 18 expression loses the suppressive ability of interaction between PDK1 (show PDK1 Antibodies) and Akt (show AKT1 Antibodies) and causes sustained phosphorylation of Akt (show AKT1 Antibodies), resulting in the disordered proliferation in lung squamous carcinoma cells

  2. Data suggest that claudin-18 suppresses the abnormal proliferation and motility of lung epithelial cells mediated by inhibition of phosphorylation of pyruvate dehydrogenase kinase isoform 1 (PDK1 (show PDK1 Antibodies)) and proto-oncogene (show RAB1A Antibodies) protein c (show PROC Antibodies)-akt (Akt (show AKT1 Antibodies)).

  3. Human fetal lungs at 23-24 weeks gestational age, the highest-risk period for developing bronchopulmonary dysplasia, a disease of impaired alveolarization, had significantly lower CLDN18 expression relative to postnatal lungs.

  4. Evaluated expression of claudins in gastric cancer and determined their significance for patient outcome. Claudin-3 (show CLDN3 Antibodies) and claudin-7 (show CLDN7 Antibodies) were expressed in 25.4% and 29.9% of gastric cancer tissues; 51.5% of gastric cancer tissues had reduced claudin-18.

  5. High levels of CLDN18 are associated with non-small-cell lung cancer.

  6. Downregulation of miR (show MLXIP Antibodies)-1303 can inhibit proliferation, migration and invasion of gastric cancer cells by targeting CLDN18.

  7. Claudin-18 positivity is a specific phenotype that is characteristic of intestinal-type Mucinous borderline tumours of the ovary

  8. Down-regulation of claudin-18 is associated with the proliferative and invasive potential of gastric cancer.

  9. Reduced expression of olfactomedin 4 (show OLFM4 Antibodies) and ectopic expression of claudin-18 might be useful markers in the differential diagnosis of serrated polyps.

  10. Claudin 10 (show CLDN10 Antibodies)/18 are most commonly expressed in lung adenocarcinomas. Female patients and non-smokers express these claudins more commonly suggesting that they may play a part in the carcinogenesis of tobacco unrelated carcinoma.

Mouse (Murine) Claudin 18 (CLDN18) interaction partners

  1. The claudin-18 knockout mice exhibited decreased P2X7 (show P2RX7 Antibodies) mRNA transcript abundance as measured by mRNA expression microarray

  2. CLDN18 deficiency results in epithelial barrier dysfunction, injury, and impaired alveolarization in mice.

  3. Identify a role for claudin 18 in alveolar fluid homeostasis beyond its direct contributions to barrier properties.

  4. we conclude that the estrogen effects on osteoclasts may in part be mediated via regulation of Cldn-18 signaling

  5. Claudin-18 is expressed at the variety of epithelial tissues in inner ear including Organ of Corti, stria vascularis, Reissner's membrane, spiral limbus, vestibular sensory epithelia, and dark cell area.

  6. Cldn-18 is a novel negative regulator of bone resorption and osteoclast differentiation

  7. Claudin-18 forms a paracellular barrier against H(+) in the stomach. Deficiency causes paracellular H(+) leak, up-regulation of proinflammatory cytokines, recruitment of neutrophils, and atrophic gastritis.

  8. Increased expression of claudin-18 is associated with ulcerative colitis.

Claudin 18 (CLDN18) Antigen Profile

Antigen Summary

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with Claudin 18 (CLDN18)

  • claudin 18 (cldn18) antibody
  • claudin 18 (CLDN18) antibody
  • claudin 18 (LOC100349260) antibody
  • claudin 18 (Cldn18) antibody
  • claudin-18 antibody
  • CLDN18 antibody
  • SFTA5 antibody
  • SFTPJ antibody

Protein level used designations for anti-Claudin 18 (CLDN18) Antibodies

claudin 18 , claudin-18 , surfactant associated 5 , surfactant associated protein J , surfactant, pulmonary associated protein J , claudin 18-like

398928 Xenopus laevis
429135 Gallus gallus
470935 Pan troglodytes
716628 Macaca mulatta
100349260 Oryctolagus cuniculus
51208 Homo sapiens
477079 Canis lupus familiaris
100294676 Sus scrofa
511460 Bos taurus
56492 Mus musculus
315953 Rattus norvegicus
101112106 Ovis aries
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