Browse our Claudin 18 (CLDN18) ELISA Kits

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Claudin 18 ELISA Kits (CLDN18)
On www.antibodies-online.com are 25 Claudin 18 (CLDN18) ELISA Kits from 6 different suppliers available. Additionally we are shipping Claudin 18 Antibodies (60) and Claudin 18 Proteins (4) and many more products for this protein. A total of 94 Claudin 18 products are currently listed.
Synonyms:
claudin-18, CLDN18, SFTA5, SFTPJ
list all ELISA KIts Gene Name GeneID UniProt
CLDN18 51208 P56856
CLDN18 56492 P56857
CLDN18 315953  

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More ELISA Kits for Claudin 18 Interaction Partners

Human Claudin 18 (CLDN18) interaction partners

  1. The presented data substantiate the hypothesis that claudin-18 is a central barrier-forming component of tight junctions and show that IL-13 (show IL13 ELISA Kits) downregulates claudin-18. These data also suggest that the loss of claudin-18 is associated with increased sensitization to aeroantigens and airway responsiveness

  2. suggest that the reduction of CLDN5 (show CLDN5 ELISA Kits), 7, and 18 expression loses the suppressive ability of interaction between PDK1 (show PDK1 ELISA Kits) and Akt (show AKT1 ELISA Kits) and causes sustained phosphorylation of Akt (show AKT1 ELISA Kits), resulting in the disordered proliferation in lung squamous carcinoma cells

  3. Data suggest that claudin-18 suppresses the abnormal proliferation and motility of lung epithelial cells mediated by inhibition of phosphorylation of pyruvate dehydrogenase kinase isoform 1 (PDK1 (show PDK1 ELISA Kits)) and proto-oncogene (show RAB1A ELISA Kits) protein c (show PROC ELISA Kits)-akt (Akt (show AKT1 ELISA Kits)).

  4. Human fetal lungs at 23-24 weeks gestational age, the highest-risk period for developing bronchopulmonary dysplasia, a disease of impaired alveolarization, had significantly lower CLDN18 expression relative to postnatal lungs.

  5. Evaluated expression of claudins in gastric cancer and determined their significance for patient outcome. Claudin-3 (show CLDN3 ELISA Kits) and claudin-7 (show CLDN7 ELISA Kits) were expressed in 25.4% and 29.9% of gastric cancer tissues; 51.5% of gastric cancer tissues had reduced claudin-18.

  6. High levels of CLDN18 are associated with non-small-cell lung cancer.

  7. Downregulation of miR (show MLXIP ELISA Kits)-1303 can inhibit proliferation, migration and invasion of gastric cancer cells by targeting CLDN18.

  8. Claudin-18 positivity is a specific phenotype that is characteristic of intestinal-type Mucinous borderline tumours of the ovary

  9. Down-regulation of claudin-18 is associated with the proliferative and invasive potential of gastric cancer.

  10. Reduced expression of olfactomedin 4 (show OLFM4 ELISA Kits) and ectopic expression of claudin-18 might be useful markers in the differential diagnosis of serrated polyps.

Mouse (Murine) Claudin 18 (CLDN18) interaction partners

  1. The presented data substantiate the hypothesis that claudin-18 is a central barrier-forming component of tight junctions and show that IL-13 (show IL13 ELISA Kits) downregulates claudin-18. These data also suggest that the loss of claudin-18 is associated with increased sensitization to aeroantigens and airway responsiveness

  2. The claudin-18 knockout mice exhibited decreased P2X7 (show P2RX7 ELISA Kits) mRNA transcript abundance as measured by mRNA expression microarray

  3. CLDN18 deficiency results in epithelial barrier dysfunction, injury, and impaired alveolarization in mice.

  4. Identify a role for claudin 18 in alveolar fluid homeostasis beyond its direct contributions to barrier properties.

  5. we conclude that the estrogen effects on osteoclasts may in part be mediated via regulation of Cldn-18 signaling

  6. Claudin-18 is expressed at the variety of epithelial tissues in inner ear including Organ of Corti, stria vascularis, Reissner's membrane, spiral limbus, vestibular sensory epithelia, and dark cell area.

  7. Cldn-18 is a novel negative regulator of bone resorption and osteoclast differentiation

  8. Claudin-18 forms a paracellular barrier against H(+) in the stomach. Deficiency causes paracellular H(+) leak, up-regulation of proinflammatory cytokines, recruitment of neutrophils, and atrophic gastritis.

  9. Increased expression of claudin-18 is associated with ulcerative colitis.

Claudin 18 (CLDN18) Antigen Profile

Antigen Summary

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with Claudin 18 (CLDN18)

  • claudin 18 (cldn18) Elisa Kit
  • claudin 18 (CLDN18) Elisa Kit
  • claudin 18 (LOC100349260) Elisa Kit
  • claudin 18 (Cldn18) Elisa Kit
  • claudin-18 Elisa Kit
  • CLDN18 Elisa Kit
  • SFTA5 Elisa Kit
  • SFTPJ Elisa Kit

Protein level used designations for Claudin 18 (CLDN18) ELISA Kits

claudin 18 , claudin-18 , surfactant associated 5 , surfactant associated protein J , surfactant, pulmonary associated protein J , claudin 18-like

GENE ID SPECIES
398928 Xenopus laevis
429135 Gallus gallus
470935 Pan troglodytes
716628 Macaca mulatta
100349260 Oryctolagus cuniculus
51208 Homo sapiens
477079 Canis lupus familiaris
100294676 Sus scrofa
511460 Bos taurus
56492 Mus musculus
315953 Rattus norvegicus
101112106 Ovis aries
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