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Browse our anti-Gap Junction Protein, beta 1, 32kDa (GJB1) Antibodies

Full name:
anti-Gap Junction Protein, beta 1, 32kDa Antibodies (GJB1)
On www.antibodies-online.com are 148 Gap Junction Protein, beta 1, 32kDa (GJB1) Antibodies from 18 different suppliers available. Additionally we are shipping Gap Junction Protein, beta 1, 32kDa Proteins (4) and Gap Junction Protein, beta 1, 32kDa Kits (1) and many more products for this protein. A total of 158 Gap Junction Protein, beta 1, 32kDa products are currently listed.
Synonyms:
AI118175, CMTX, CMTX1, Cnx32, connexin-30, connexin32, cx30, Cx32, gja1, Gjb-1, GJB1, gjb1-a, GJIC

All available anti-Gap Junction Protein, beta 1, 32kDa Antibodies

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Top referenced anti-Gap Junction Protein, beta 1, 32kDa Antibodies

  1. Human Monoclonal GJB1 Primary Antibody for IHC (fro), WB - ABIN1107368 : Corcos, Lafrenière, Begy, Loch-Caruso, Willard, Glover: Refined localization of human connexin32 gene locus, GJB1, to Xq13.1. in Genomics 1992 (PubMed)
    Show all 3 references for ABIN1107368

  2. Cow (Bovine) Polyclonal GJB1 Primary Antibody for IHC, WB - ABIN2774855 : Dagli, Yamasaki, Krutovskikh, Omori: Delayed liver regeneration and increased susceptibility to chemical hepatocarcinogenesis in transgenic mice expressing a dominant-negative mutant of connexin32 only in the liver. in Carcinogenesis 2004 (PubMed)

More Antibodies against Gap Junction Protein, beta 1, 32kDa Interaction Partners

Mouse (Murine) Gap Junction Protein, beta 1, 32kDa (GJB1) interaction partners

  1. The results of this study indicated that the Leu89Pro substitution in the second transmembrane domain of CX32 disrupts the trafficking of the protein, inhibiting the assembly of CX32 gap junctions, which in turn may result in peripheral neuropathy.

  2. We show that the cell-surface and secreted isoforms of CSF-1 (show CSF1 Antibodies) have opposing effects on macrophage activation and disease progression in a mouse model of connexin32-deficientconnexin32-deficient mice

  3. Results identify CSF-1 (show CSF1 Antibodies)-activated macrophages as crucial mediators of detrimental Schwann cell dedifferentiation in Cx32-deficient mice

  4. Blockade of endothelial Cx32 increased tissue factor (show F3 Antibodies) expression induced by TNF-alpha (show TNF Antibodies) stimulation and cell-cell interaction via ICAM1 (show ICAM1 Antibodies). Direct Cx32-mediated interaction modulates TF expression in ECs during vascular inflammation.

  5. These findings support a role for Cx32 in non-myelinating and regenerating populations of Schwann cells in normal axonal maintenance in re-myelination, and regeneration of peripheral nerve following injury

  6. Connexin32 interacts with connexin26 (show GJB2 Antibodies) and the mitochondrial protein (show COX6B2 Antibodies), sideroflexin-1 (show SFXN1 Antibodies), at the plasma membrane forming a novel signaling nexus.

  7. These results demonstrate that the incidence of hepatocellular carcinoma increases only in male Cx32KO mice, presumably due to enhanced tumor promotion and progression signals associated with Cx32 deficiency.

  8. Cx32 is differentially phosphorylated and exists in a complex with SAP97 (show DLG1 Antibodies) and CaM (show Calm2 Antibodies).

  9. Cx32 therapy improves gap junctional conductance results in larger infarct size, and no antiarrhythmic efficacy.

  10. Connexin 36 (show GJD2 Antibodies) is expressed in beta and connexins 26 and 32 in acinar cells at the end of the secondary transition of mouse pancreatic development and increase during fetal and perinatal life.

Human Gap Junction Protein, beta 1, 32kDa (GJB1) interaction partners

  1. In summary, Cx32 is involved in cisplatin resistance, and cytoplasmic Cx32 plays an important role in chemoresistance.

  2. Mutations in noncoding DNA of GJB1 are a major cause of CMTX1 and highlight the importance of mutations in noncoding DNA in human disease.

  3. NMR study of N-terminal mutants of Connexin 26 (show GJB2 Antibodies) and Connexin 32

  4. Knockdown of Cx32 by shRNA in HepG2 cells induced EMT (show ITK Antibodies), while overexpression of Cx32 converted EMT (show ITK Antibodies) to mesenchymal-epithelial transition (MET) in the HepG2/DOX cells. These results suggest that Cx32 is an important regulator of DOX-induced EMT (show ITK Antibodies) in hepatocellular carcinoma . Cx32 could be considered as a novel target to reverse DOX resistance in hepatocellular carcinoma

  5. The three novel missense mutations within the GJB1 gene broaden the mutational diversity of X-linked Charcot-Marie-Tooth Disease type I (CMT1X).

  6. A novel point mutation in GJB1 was detected, expanding the spectrum of GJB1 mutations known to be associated with CMTX.

  7. Complete loss of connexin32 function is sufficient to produce central nervous system dysfunction with clinical manifestations.

  8. This study reveals for the first time that Cx43 (show GJA1 Antibodies) and Cx32 are down-regulated in keratocystic odontogenic tumours

  9. Transgenic expression of hCx32 in Cx32/Cx47dKO mice resulted in almost complete rescue of behavioral abnormalities in a hypomyelinating leukodystrophy model.

  10. No mutations were found in GJB1 in a cohort of 38 Italian CMT2 patients.

Cow (Bovine) Gap Junction Protein, beta 1, 32kDa (GJB1) interaction partners

  1. intermediate invasive status of bovine trophoblast is supported by the fact that trophoblast giant cells coexpress connexins (Cx)26 (show GJB2 Antibodies), Cx32, and Cx43 (show GJA1 Antibodies)

Gap Junction Protein, beta 1, 32kDa (GJB1) Antigen Profile

Antigen Summary

This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with Gap Junction Protein, beta 1, 32kDa (GJB1)

  • gap junction protein, beta 1, 32kDa (gjb1) antibody
  • connexin 32 (CX32) antibody
  • connexin 32 (ARALYDRAFT_491086) antibody
  • gap junction protein, beta 1, 32kDa (GJB1) antibody
  • gap junction protein, beta 1 (Gjb1) antibody
  • AI118175 antibody
  • CMTX antibody
  • CMTX1 antibody
  • Cnx32 antibody
  • connexin-30 antibody
  • connexin32 antibody
  • cx30 antibody
  • Cx32 antibody
  • gja1 antibody
  • Gjb-1 antibody
  • GJB1 antibody
  • gjb1-a antibody
  • GJIC antibody

Protein level used designations for GJB1

connexin 30 , connexin 32 , gap junction protein, beta 1, 32kDa , connexin-32 , connexin-43 , gap junction beta-1 protein , gap junction membrane channel protein beta 1 , GAP junction 28 kDa liver protein , connexin32 , cx32 , gap junction protein, beta 1, 32 kD , gap junction protein beta 1 , connexin-30 , cx30

GENE ID SPECIES
407921 Xenopus (Silurana) tropicalis
443234 Ovis aries
9303136 Arabidopsis lyrata subsp. lyrata
465696 Pan troglodytes
706327 Macaca mulatta
14618 Mus musculus
29584 Rattus norvegicus
100379282 Cavia porcellus
2705 Homo sapiens
378797 Gallus gallus
480953 Canis lupus familiaris
281194 Bos taurus
100008934 Oryctolagus cuniculus
100034021 Equus caballus
394373 Xenopus laevis
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