Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Our findings confirm the role of Talin-1 (show TLN1 ELISA Kits) in carcinogenesis and provided a set of novel therapeutic targets for the treatment of hepatocellular carcinoma
These data show that TLN1 (show TLN1 ELISA Kits) can act as a viral restriction factor that suppresses hepatitis B virus replication, and suggest that the HBx relieves this restriction by inducing TLN1 (show TLN1 ELISA Kits) degradation.
The ERK (show EPHB2 ELISA Kits) pathway was responsible for these promoting effects of Talin1 knockdown in HCC (show FAM126A ELISA Kits) cells.
Here the authors identify neuron-specific intercellular adhesion molecule 5 (ICAM-5/telencephalin) as a cellular receptor for sialic acid-dependent and -independent entry of enterovirus D68.
This study showed that serum sTalin-1 levels were associated with a sustained increase in disability after MS attack but not with serum anti-Talin-1 (show TLN1 ELISA Kits) antibody levels.
The Rap1 (show RABGEF1 ELISA Kits)-RIAM (show APBB1IP ELISA Kits)-talin axis of integrin activation and blood cell function
These findings suggested that Talin-1 (show TLN1 ELISA Kits) protein was significantly upregulated in PCa (show FLVCR1 ELISA Kits) tissues compared with that of BPH (show GLI3 ELISA Kits) tissue and Talin-1 (show TLN1 ELISA Kits) expression was an independent predictor for lymph node metastasis and biochemical recurrence of PCa (show FLVCR1 ELISA Kits).
Serum talin-1 (show TLN1 ELISA Kits) had 97.7% sensitivity.
Both TLN-1 (show TLN1 ELISA Kits) and TLN-2 (show TLN2 ELISA Kits) levels correlate with tumorigenicity in human HCC (show FAM126A ELISA Kits), indicating that these molecules constitute important molecular targets for the diagnosis and/or treatment of hepatocellular carcinoma .
TLN1 (show TLN1 ELISA Kits) significantly increases in refractory glioblastoma multiforme
FAK sustained the active integrin conformation by maintaining talin association with Rab11 endosomes in a type I phosphatidylinositol phosphate kinase (PIPKIgamma)-dependent manner.
These findings show that talin and kindlin cooperatively activate integrins leading to fibronectin (show FN1 ELISA Kits) binding and adhesion.
Data show that estradiol or bisphenol A decreased expression of luteinizing hormone beta (Lhb (show LHB ELISA Kits)), follicle stimulating hormone beta (Fshb (show FSHB ELISA Kits)), and intracellular adhesion molecule (show NCAM1 ELISA Kits)-5 (Icam5) in females but only decreased expression of Icam5 in males.
Binding of vinculin (show VCL ELISA Kits) to the R1-R3 region of the talin rod is important for focal adhesion stability.
Data indicate that talin mechanics are isoform specific so that expression of either talin-1 (show TLN1 ELISA Kits) or talin-2 (show TLN2 ELISA Kits) modulates extracellular rigidity sensing.
Conformational activation of talin by PREL-1 (show APBB1IP ELISA Kits) triggers integrin-mediated cell adhesion.
Direct methylation of talin, a key regulatory molecule in cell migration, by Ezh2 disrupted the binding of talin to F-actin and thereby promoted the turnover of adhesion structures.
This study revealed a similar expression of ICAM-5 in dendritic elements at P14 (show PCOLCE ELISA Kits) and P28 (show GSTO1 ELISA Kits); however, an increased prevalence of ICAM-5 was noted in dendritic protrusions at P28 (show GSTO1 ELISA Kits) in the MMP-9 (show MMP9 ELISA Kits) null animals
reduction of talin-beta3 integrin (show ITGB3 ELISA Kits) binding affinity results in decelerated alphaIIbbeta3 integrin activation and protection from arterial thrombosis without pathological bleeding
Results suggest that the interaction between ICAM-5 and beta1 integrins is important in formation of functional synapses.
This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
intercellular adhesion molecule 5
, intercellular adhesion molecule 3