Browse our anti-Junction Plakoglobin (JUP) Antibodies

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anti-Junction Plakoglobin Antibodies (JUP)
On are 349 Junction Plakoglobin (JUP) Antibodies from 27 different suppliers available. Additionally we are shipping Junction Plakoglobin Kits (16) and Junction Plakoglobin Proteins (5) and many more products for this protein. A total of 380 Junction Plakoglobin products are currently listed.
ARVD12, cb80, CTNNG, D930025P04Rik, danPG, DP3, DPIII, fb11b06, jup, PDGB, PG, PKGB, plak, wu:fb11b06

All available anti-Junction Plakoglobin Antibodies

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Top referenced anti-Junction Plakoglobin Antibodies

  1. Chicken Monoclonal JUP Primary Antibody for IHC (fro), IF - ABIN112236 : Akat, Mennel, Kremer, Gassler, Bleck, Kartenbeck: Molecular characterization of desmosomes in meningiomas and arachnoidal tissue. in Acta neuropathologica 2003 (PubMed)
    Show all 13 references for 112236

  2. Human Monoclonal JUP Primary Antibody for IF, WB - ABIN395700 : Pryczynicz, Guzińska-Ustymowicz, Kemona, Czyzewska: Expression of the E-cadherin-catenin complex in patients with pancreatic ductal adenocarcinoma. in Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society 2010 (PubMed)
    Show all 5 references for 395700

  3. Chicken Monoclonal JUP Primary Antibody for IF, IP - ABIN967860 : Mary, Charrasse, Meriane, Comunale, Travo, Blangy, Gauthier-Rouvière: Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism. in Molecular biology of the cell 2002 (PubMed)
    Show all 5 references for 967860

  4. Chicken Monoclonal JUP Primary Antibody for IHC (fro), IF - ABIN1107897 : Kolligs, Kolligs, Hajra, Hu, Tani, Cho, Fearon: gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. in Genes & development 2000 (PubMed)
    Show all 2 references for 1107897

  5. Human Polyclonal JUP Primary Antibody for ELISA, WB - ABIN249574 : Knudsen, Wheelock: Plakoglobin, or an 83-kD homologue distinct from beta-catenin, interacts with E-cadherin and N-cadherin. in The Journal of cell biology 1992 (PubMed)

  6. Human Polyclonal JUP Primary Antibody for FACS, IHC (p) - ABIN652942 : Arnemann, Spurr, Wheeler, Parker, Buxton: Chromosomal assignment of the human genes coding for the major proteins of the desmosome junction, desmoglein DGI (DSG), desmocollins DGII/III (DSC), desmoplakins DPI/II (DSP), and plakoglobin DPIII (JUP). in Genomics 1991 (PubMed)

More Antibodies against Junction Plakoglobin Interaction Partners

Human Junction Plakoglobin (JUP) interaction partners

  1. Plakoglobin maintains the integrity of vascular endothelial cell junctions and regulates VEGF (show VEGFA Antibodies)-induced phosphorylation of VE-cadherin (show CDH5 Antibodies)

  2. In JUP mutations are the frequent cause of Arrhythmogenic cardiomyopathy, isolated Brugada syndrome can appear due to reduced sodium channel activities.

  3. investigated the in vitro tumor/metastasis suppressor effects of plakoglobin in ovarian cancer cell lines with mutant p53 expression and different cadherin profiles

  4. Reduced plakoglobin staining in intercalated discs of heart tissue from human arrhythmogenic right ventricular cardiomyopathy (ARVC) patients and in a murine ARVC model is caused by alterations in epitope accessibility and not by protein relocalization

  5. Idiopathic pulmonary fibrosis lung fibroblasts expressed less Pkgb protein than control fibroblasts, but characteristic fibroblast phenotypes (adhesion, proliferation, and apoptosis) were not controlled by Pkgb expression.

  6. Immunostaining for plakoglobin might serve as an additional diagnostic marker of arrhythmogenic right ventricular cardiomyopathy in forensic pathology.

  7. Expression of gamma-catenin in NSCLC cells resulted in reduced cell migration as determined by both scratch assays and trans-well cell migration assays.

  8. Six variants of uncertain clinical significance in the PKP2 (show PKP2 Antibodies), JUP, and DSG2 (show DSG2 Antibodies) genes showed a deleterious effect on mRNA splicing, indicating these are ARVD (show TGFB3 Antibodies)/C-related pathogenic splice site mutations.

  9. gamma-catenin is a tumor suppressor in esophageal squamous cell carcinoma and may serve as a prognostic marker

  10. Immunohistochemical analysis of plakoglobin had a relatively high sensitivity and specificity in arrhythmogenic right ventricular cardiomyopathy, but could not be relied upon as a diagnostic test for ARVC.

Mouse (Murine) Junction Plakoglobin (JUP) interaction partners

  1. Reduced plakoglobin staining in intercalated discs of heart tissue from human arrhythmogenic right ventricular cardiomyopathy (ARVC) patients and in a murine ARVC model is caused by alterations in epitope accessibility and not by protein relocalization

  2. Mice with hepatic loss of the desmosomal protein gamma-Catenin are prone to cholestatic injury and chemical carcinogenesis.

  3. EMMPRIN ensures proper actomyosin-driven maturation of competent endothelial junctions by forming a molecular complex with gamma-catenin (also known as junction plakoglobin) and Nm23 (also known as NME1), a nucleoside diphosphate kinase

  4. In 2 knockin mouse models, endogenous Jup was engineered to express the Naxos-associated form of plakoglobin. Insufficiency of the truncated Naxos plakoglobin, rather than gain of function, accounted for cardiac disease manifestations.

  5. plakoglobin (Pg) in conjunction with lymphoid enhancer-binding factor 1 (Lef-1 (show LEF1 Antibodies)) differentially regulates the proximal promoters of Dsc2 (show DSC2 Antibodies) and Dsc3 (show DSC3 Antibodies)

  6. our study reveals a function for gamma-catenin in the regulation of mESC differentiation and has implications for human cancers in which gamma-catenin is mutated and/or aberrantly expressed.

  7. The data suggest novel function(s) for plakoglobin (PG) beyond the heart and define a critical threshold of PG expression that is necessary for postnatal survival.

  8. decreased plakoglobin expression increases the invasive behavior of breast cancer cells; this is the first demonstration of a functional role for plakoglobin/gamma-catenin in the metastatic process

  9. The cadherin-catenin signaling pathway was inactivated in spinal motor neurons to assess the significance of motor neuron position in motor circuit assembly; genetic inactivation of both beta- and gamma-catenin or N-cadherin (show CDH2 Antibodies), disrupts motor neuron positioning.

  10. Lack of plakoglobin in epidermis leads to keratoderma.

Zebrafish Junction Plakoglobin (JUP) interaction partners

  1. Although plakoglobin is clearly present during normal odontogenesis, the loss of plakoglobin does not influence tooth development.

  2. plakoglobin localization in the heart region shifts from adherens junctions to desmosomes during heart chamber development

  3. knockdown of plakoglobin in zebrafish results in decreased heart size, reduced heartbeat, cardiac oedema, reflux of blood between heart chambers and a twisted (show POMT2 Antibodies) tail

Junction Plakoglobin (JUP) Antigen Profile

Antigen Summary

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene\; however, not all transcripts have been fully described.

Alternative names and synonyms associated with Junction Plakoglobin (JUP)

  • junction plakoglobin (jup) antibody
  • junction plakoglobin (Tsp_06656) antibody
  • junction plakoglobin (JUP) antibody
  • Junction plakoglobin (plak) antibody
  • junction plakoglobin (Jup) antibody
  • junction plakoglobin (jup-b) antibody
  • junction plakoglobin a (jupa) antibody
  • ARVD12 antibody
  • cb80 antibody
  • CTNNG antibody
  • D930025P04Rik antibody
  • danPG antibody
  • DP3 antibody
  • DPIII antibody
  • fb11b06 antibody
  • jup antibody
  • PDGB antibody
  • PG antibody
  • PKGB antibody
  • plak antibody
  • wu:fb11b06 antibody

Protein level used designations for JUP

desmoplakin 3 , junction plakoglobin , Junction plakoglobin , junction plakoglobin-like , plakoglobin , catenin (cadherin-associated protein), gamma 80kDa , desmoplakin III , desmoplakin-3 , gamma-catenin , gamma-catenin (plakoglobin) , gama-catenin

395011 Xenopus (Silurana) tropicalis
398496 Xenopus laevis
10909874 Trichinella spiralis
100012969 Monodelphis domestica
100194931 Salmo salar
100345709 Oryctolagus cuniculus
100440279 Pongo abelii
100564925 Anolis carolinensis
429710 Gallus gallus
3728 Homo sapiens
445543 Bos taurus
16480 Mus musculus
81679 Rattus norvegicus
480522 Canis lupus familiaris
397592 Sus scrofa
399278 Xenopus laevis
30415 Danio rerio
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