You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our SCRIB (SCRIB) ELISA Kits

Full name:
Scribbled Homolog (Drosophila) ELISA Kits (SCRIB)
On www.antibodies-online.com are 1 Scribbled Homolog (Drosophila) (SCRIB) ELISA Kits from 1 different suppliers available. Additionally we are shipping SCRIB Antibodies (24) and and many more products for this protein. A total of 28 SCRIB products are currently listed.
Synonyms:
0424/05, AI118201, CG5462, CG5467, CG31082, CG42614, CG43398, Crc, CRIB, CRIB1, CT17324, Dmel\\CG43398, Dmel_CG5462, Dmel_CG5467, Dmel_CG31082, Dmel_CG42614, ird, ird15, l(3)673, l(3)c00119, l(3)j7B3, l(3)S042405, MENE (3R)-F, mKIAA0147, Scb, SCR, scrb, SCRB1, Scrib, SCRIB1, scribble, scribble1, si:ch211-12p8.1, si:zc12p8.1, smi97B, vart, Vartul
list all ELISA KIts Gene Name GeneID UniProt
SCRIB 105782 Q80U72
Human SCRIB SCRIB 23513 Q14160

Show all species

Show all synonyms

SCRIB (SCRIB) ELISA Kits by Reactivity

Select your species

More ELISA Kits for SCRIB Interaction Partners

Fruit Fly (Drosophila melanogaster) Scribbled Homolog (Drosophila) (SCRIB) interaction partners

  1. Our data reveal that the basolateral determinant Scribbled (Scrib) is required for PCV formation through optimizing BMP (show TGFb ELISA Kits) signaling. Scrib regulates BMP (show TGFb ELISA Kits)-type I receptor Thickveins (Tkv) localization at the basolateral region of PCV cells and subsequently facilitates Tkv internalization to Rab5 (show RAB5A ELISA Kits) endosomes, where Tkv is active

  2. Scrib module regulates epithelial polarity by influencing endocytic itineraries of Crumbs and other retromer-dependent cargo.

  3. Loss of scrib, dlg (show DLG4 ELISA Kits) and lgl had no effect on gonad formation, but Dlg (show DLG4 ELISA Kits) and Scrib in the gonadal mesoderm acted critically in the somatic wrapping of the pole cells and the internal structure of the Drosophila embryonic gonads.

  4. Drosophila scrib acts downstream of the Fat (Ft) receptor, and requires Hippo signaling for its growth regulatory functions.

  5. Loss of Scrib promotes Yorkie (show YAP1 ELISA Kits)/Scalloped-dependent epithelial tissue overgrowth, and this is also important for driving cooperative tumor overgrowth with oncogenic Ras-Raf (show RAF1 ELISA Kits) signaling.

  6. Data show that mutations causing the loss of Salvador (Sav (show SAV1 ELISA Kits)) or Scribble (Scrib) or activation of Ras transform normal stem cells into cancer stem cells through a multistep process in the adult Drosophila Malpighian tubules.

  7. interaction between Ras(V12) and scrib(-) clones involves JNK (show MAPK8 ELISA Kits) signalling propagation and JNK (show MAPK8 ELISA Kits)-induced upregulation of JAK (show JAK3 ELISA Kits)/STAT (show STAT1 ELISA Kits)-activating cytokines, a compensatory growth mechanism for tissue homeostasis

  8. These results demonstrate distinct aPKC and JNK (show MAPK8 ELISA Kits)-dependent pathways through which loss of Scrib promotes tumourigenesis in Drosophila.

  9. Study provide evidence that scrib and dlg (show DLG4 ELISA Kits) function differentially in anterior and posterior patterning of the follicular epithelium at oogenesis. Further genetic analysis indicates that scrib and dlg (show DLG4 ELISA Kits) act in a common pathway to regulate PFC (show CFP ELISA Kits) fate induction.

  10. conclude that Dlg (show DLG4 ELISA Kits)/Scrib/Lgl are important in regulating cortical polarity, cell size asymmetry and mitotic spindle asymmetry in Drosophila neuroblasts

Mouse (Murine) Scribbled Homolog (Drosophila) (SCRIB) interaction partners

  1. SCRIB uncouples reactive oxygen species-dependent bacterial killing activity from M1 polarization and inflammatory functions of macrophages

  2. we provide genetic evidence of a unique link between skin carcinogenesis and loss of the epithelial polarity regulator Scrib, emphasizing that Scrib exerts a wide-spread tumor suppressive function in epithelia.

  3. The polarity protein Scribble regulates myelination and remyelination in the central nervous system.

  4. Scrib is a regulator of tissue stem cells, controlling population expansion and self-renewal with Scrib expression dynamics directing satellite cell fate.

  5. Scrib is a novel proinflammatory regulator in endothelial cells, which maintains the protein expression of GATA-like protein-1.

  6. The Scrib-Rac1 interaction plays a crucial role in the organization of developing cardiomyocytes and formation of the ventricular myocardium.

  7. We show that loss of Scrib and activated oncogenic KRas cooperate in vivo, resulting in more aggressive lung tumors

  8. findings, based on a definitive genetic mouse model provide fundamental insights into mammary duct maturation and homeostasis and reveal that Scrib loss activates a MAPK (show MAPK1 ELISA Kits)/Fra1 (show FOSL1 ELISA Kits) pathway that alters mammary progenitor activity

  9. The Scribble knockout fetus exhibits exomphalos (intact and ruptured), in contrast to the original published phenotype of gastroschisis.

  10. Scrib is required to maintain epithelial identity and that loss of Scrib can culminate in EMT (show ITK ELISA Kits), mediated, at least in part, through TGFbeta (show TGFB1 ELISA Kits) signaling.

Zebrafish Scribbled Homolog (Drosophila) (SCRIB) interaction partners

  1. Zygotic expression of Scribble1 (scrb1) is required for migration of the nVII motor neurons mainly in a non cell-autonomous manner, while maternal expression is required for convergent extension movements during gastrulation.

  2. Suppression of scrib and puf60 in zebrafish (show PUF60 ELISA Kits)leads to reduction in body length, small head size, and craniofacial defects.

  3. It was found that Scribble is required for oriented cell division and that its function in this process is independent of canonical apicobasal and planar polarity pathways.

  4. Lpp interacts with the PCP (show PRCP ELISA Kits) protein Scrib in zebrafish, and that Lpp and Scrib cooperate for the mediation of convergence and extension.

  5. Scribble is a candidate link between Fat and the Hippo signaling cascade in vertebrates

Human Scribbled Homolog (Drosophila) (SCRIB) interaction partners

  1. SCRIB uncouples reactive oxygen species-dependent bacterial killing activity from M1 polarization and inflammatory functions of macrophages

  2. The Palmitoylation-deficient mutants of SCRIB were mislocalized, leading to disruption of cell polarity and loss of their tumor-suppressive activities to oncogenic YAP (show YAP1 ELISA Kits), MAPK (show MAPK1 ELISA Kits) and PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) pathways.

  3. Data show hepatitis C virus (HCV) nonstructural protein 4B (NS4B) PDZ (show INADL ELISA Kits)-binding motif (PBM) promotes the colony formation of hepatoma cells by degrading human Scribble protein.

  4. the inclusion/exclusion of specific SCRIB exons is a mechanistic hallmark of breast cancer, which could potentially be exploited to develop more efficient diagnostics and therapies.

  5. loss of Scribble-induced HuR (show ELAVL1 ELISA Kits) translocation mediates the accumulation of Snail (show SNAI1 ELISA Kits) via activation of the p38 MAPK (show MAPK14 ELISA Kits) pathway.

  6. The two PDZ (show INADL ELISA Kits) domains within the PDZ34 tandem of Scribble, a cell polarity regulator, tightly pack in a 'front-to-back' mode to form a compact supramodule.

  7. We show that loss of Scrib and activated oncogenic KRas cooperate in vivo, resulting in more aggressive lung tumors

  8. High levels of mislocalized SCRIB functions as a neomorph to promote mammary tumorigenesis.

  9. miR (show MLXIP ELISA Kits)-296-5p/SCRIB axis plays a role in breast carcinogenesis

  10. This study demonstrated that rare deleterious mutations of SCRIB may contribute to the multifactorial risk for human spina bifida.

SCRIB Antigen Profile

Antigen Summary

This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Alternative names and synonyms associated with SCRIB

  • scribbled (scrib) Elisa Kit
  • scribbled homolog (Drosophila) (Scrib) Elisa Kit
  • scribbled homolog (Drosophila) (scrib) Elisa Kit
  • scribbled planar cell polarity protein (SCRIB) Elisa Kit
  • 0424/05 Elisa Kit
  • AI118201 Elisa Kit
  • CG5462 Elisa Kit
  • CG5467 Elisa Kit
  • CG31082 Elisa Kit
  • CG42614 Elisa Kit
  • CG43398 Elisa Kit
  • Crc Elisa Kit
  • CRIB Elisa Kit
  • CRIB1 Elisa Kit
  • CT17324 Elisa Kit
  • Dmel\\CG43398 Elisa Kit
  • Dmel_CG5462 Elisa Kit
  • Dmel_CG5467 Elisa Kit
  • Dmel_CG31082 Elisa Kit
  • Dmel_CG42614 Elisa Kit
  • ird Elisa Kit
  • ird15 Elisa Kit
  • l(3)673 Elisa Kit
  • l(3)c00119 Elisa Kit
  • l(3)j7B3 Elisa Kit
  • l(3)S042405 Elisa Kit
  • MENE (3R)-F Elisa Kit
  • mKIAA0147 Elisa Kit
  • Scb Elisa Kit
  • SCR Elisa Kit
  • scrb Elisa Kit
  • SCRB1 Elisa Kit
  • Scrib Elisa Kit
  • SCRIB1 Elisa Kit
  • scribble Elisa Kit
  • scribble1 Elisa Kit
  • si:ch211-12p8.1 Elisa Kit
  • si:zc12p8.1 Elisa Kit
  • smi97B Elisa Kit
  • vart Elisa Kit
  • Vartul Elisa Kit

Protein level used designations for SCRIB

CG43398-PA , CG43398-PB , CG43398-PC , CG43398-PD , CG43398-PH , CG43398-PI , CG43398-PJ , CG43398-PK , CG43398-PL , CG43398-PM , CG43398-PN , CG43398-PO , CG43398-PP , CG43398-PQ , CG43398-PR , CG43398-PS , CG43398-PT , CG43398-PU , CG43398-PX , gp150-like , immune response deficient 15 , lethal (3) c00119 , scrib-PA , scrib-PB , scrib-PC , scrib-PD , scrib-PH , scrib-PI , scrib-PJ , scrib-PK , scrib-PL , scrib-PM , scrib-PN , scrib-PO , scrib-PP , scrib-PQ , scrib-PR , scrib-PS , scrib-PT , scrib-PU , scrib-PX , scribble , scribbles , smell impaired 97B , vartul , PDZ-domain protein scribble , circletail , protein scribble homolog , scribble homolog 1 , landlocked , llk , scribbled homolog

GENE ID SPECIES
44448 Drosophila melanogaster
105782 Mus musculus
368473 Danio rerio
23513 Homo sapiens
Selected quality suppliers for SCRIB (SCRIB) ELISA Kits
Did you look for something else?