Browse our TBCD Proteins (TBCD)

Full name:
Tubulin Folding Cofactor D Proteins (TBCD)
On www.antibodies-online.com are 3 Tubulin Folding Cofactor D (TBCD) Proteins from 2 different suppliers available. Additionally we are shipping TBCD Antibodies (15) and many more products for this protein. A total of 22 TBCD products are currently listed.
Synonyms:
2310057L06Rik, A030005L14Rik, mKIAA0988, SSD-1, tfcD
list all proteins Gene Name GeneID UniProt
TBCD 6904 Q9BTW9
Rat TBCD TBCD 100361417  
TBCD 108903 Q8BYA0

Show all synonyms

TBCD Proteins (TBCD) by Origin

Select your origin of interest

More Proteins for TBCD Interaction Partners

Human Tubulin Folding Cofactor D (TBCD) interaction partners

  1. variants. We identified two candidate homozygous missense variants, R942Q in the tubulin-folding cofactor D (TBCD) gene and H250Q in the bromo-adjacent homology domain and coiled-coil containing 1 (BAHCC1) gene, located on chromosome 17q25.3 with an interval of 1.4 Mbp (show MBL2 Proteins).

  2. Intractable epilepsy, intellectual disability and acquired microcephaly, and cortical atrophy and thinned corpus callosum as major MRI (show C7ORF49 Proteins) features, caused by biallelic variants in TBCD.

  3. findings establish that defective TBCD function underlies a recognizable encephalopathy and drives accelerated microtubule polymerization and enhanced microtubule stability, underscoring an additional cause of altered microtubule dynamics with impact on neuronal function and survival in the developing brain

  4. Defects of microtubule formation caused by TBCD mutations may underlie the pathomechanism of a neurodegenerative encephalopathy.

  5. Data show that bovine and human TBCD have functionally identical roles in tubulin (show TUBB Proteins) heterodimer assembly, and that the inability of human TBCD to disrupt microtubule integrity can be overcome by siRNA-mediated suppression of expression of Arl2 (show ARL2 Proteins).

  6. provides first evidence that beta-tubulin cofactor D plays a role in cells independent of its presumed role in folding tubulin (show TUBB Proteins) heterodimers

  7. Cofactor D functions as a centrosomal protein and is required for the recruitment of the gamma-tubulin (show TUBG1 Proteins) ring complex at centrosomes and organization of the mitotic spindle

Cow (Bovine) Tubulin Folding Cofactor D (TBCD) interaction partners

  1. Data show that bovine and human TBCD have functionally identical roles in tubulin (show TUBB Proteins) heterodimer assembly, and that the inability of human TBCD to disrupt microtubule integrity can be overcome by siRNA-mediated suppression of expression of Arl2 (show ARL2 Proteins).

  2. Cofactor D functions as a centrosomal protein and is required for the recruitment of the gamma-tubulin (show TUBG1 Proteins) ring complex at centrosomes and organization of the mitotic spindle

TBCD Protein Profile

Protein Summary

Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex\; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

Alternative names and synonyms associated with TBCD

  • tubulin folding cofactor D (TBCD)
  • tubulin folding cofactor D (Tbcd)
  • tubulin-specific chaperone d (Tbcd)
  • 2310057L06Rik protein
  • A030005L14Rik protein
  • mKIAA0988 protein
  • SSD-1 protein
  • tfcD protein

Protein level used designations for TBCD

beta-tubulin cofactor D , tubulin-folding cofactor D , tubulin-specific chaperone D

GENE ID SPECIES
6904 Homo sapiens
281515 Bos taurus
417334 Gallus gallus
100361417 Rattus norvegicus
108903 Mus musculus
Selected quality suppliers for TBCD Proteins (TBCD)
Did you look for something else?