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Browse our Vinculin (VCL) ELISA Kits

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Vinculin ELISA Kits (VCL)
On are 36 Vinculin (VCL) ELISA Kits from 9 different suppliers available. Additionally we are shipping Vinculin Antibodies (192) and Vinculin Proteins (17) and many more products for this protein. A total of 255 Vinculin products are currently listed.
9430097D22, AA571387, AI462105, AW545629, CG3299, CMD1W, CMH15, CT11081, DDBDRAFT_0186762, DDBDRAFT_0232320, DDB_0186762, DDB_0232320, Dmel\\CG3299, Dmvincp, EG:103B4.1, hm:zehn2160, im:6902790, LOC100228062, MV, MVCL, VCL, vcl-A, Vin, Vin2EF, vinc

Vinculin (VCL) ELISA Kits by Reactivity

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More ELISA Kits for Vinculin Interaction Partners

Human Vinculin (VCL) interaction partners

  1. The VCL-encoding protein was involved in cardiomyopathy that associated with hypertension, therefore our results suggest the rs4746172 of VCL may be a novel target for clinical interventions to reduce CVD risk by regulating blood pressure in male Chinese

  2. Three novel genes were identified as recurrently mutated; MYCN (show MYCN ELISA Kits), MYO5B and VCL, and mutations in these genes were exclusively found in malignant sympathetic paraganglioma tumors.

  3. roles and mechanisms of phospholipids in regulating the structure and function of vinculin and of its muscle-specific (show EIF3K ELISA Kits) metavinculin splice variant.

  4. Upon actin engagement, the N-terminal "strap" and helix 1 are displaced from the vinculin tail helical bundle to mediate actin bundling.

  5. This study defined a plastic relationship between vinculin-mediated tension and adhesion complex area that controls fundamental cell-matrix adhesion properties.

  6. Analysis showed that ITGB4 (show ITGB4 ELISA Kits) and VCL were upregulated in exosomes derived from taxane-resistant prostate cancer cells suggesting them as useful markers for progression of prostate cancer associated with taxane-resistance.

  7. vinculin, present in the joints of anti-citrullinated protein antibody (ACPA (show PRTN3 ELISA Kits))(+) rheumatoid arthritis patients, was identified as an autoantigen targeted by ACPA (show PRTN3 ELISA Kits) and CD4 (show CD4 ELISA Kits)(+) T cells.

  8. The activation of vinculin by stretched talin induces a positive feedback that reinforces the actin-talin-vinculin association.

  9. Data indicate that specific protein interactions are spatially segregated within focal adhesions (FAs (show FAS ELISA Kits)) at the nanoscale to regulate vinculin activation and function.

  10. Vinculin expression was found to be significantly downregulated.

Mouse (Murine) Vinculin (VCL) interaction partners

  1. Binding of vinculin to the R1-R3 region of the talin rod is important for focal adhesion stability.

  2. These data demonstrate that Src-mediated phosphorylation is necessary for vinculin activation, and that phosphorylation controls cytoskeletal mechanics by regulating force transmission between the actin cytoskeleton and focal adhesion proteins.

  3. results suggest that vinculin promotes directionally persistent cell migration and tension-dependent ECM (show MMRN1 ELISA Kits) remodeling in complex 3D environments by increasing cell-ECM (show MMRN1 ELISA Kits) adhesion and traction force generation.

  4. Force-dependent conformational switch of alpha-catenin (show CTNNA1 ELISA Kits) controls vinculin binding.

  5. Mutant vinculin expressing cells are altered in cell migration, which is accompanied by changes in cell adhesion.

  6. show that Src (show SRC ELISA Kits) phosphorylation of Y1065 within the C-terminal hairpin regulates Vt-mediated actin bundling and provide a detailed characterization of vinculin Y1065 mutations

  7. The E29R mutation might prime the vinculin head for F-actin binding, which results in higher cell stiffness, contractile force, and strengthening of focal adhesions.

  8. Vcl plays a crucial role in stabilizing gap junctions and myocyte integrity through direct interactions with ZO-1 (show TJP1 ELISA Kits) and stabilization of CX43 (show GJA1 ELISA Kits).

  9. serine phosphorylation is required for the activation of vinculin and force transmission in focal adhesions.

  10. VCL binding talin, but not Arp2 (show AICDA ELISA Kits)/3, is critical for osteoclast function, and its selective inhibition retards physiological bone loss.

Pig (Porcine) Vinculin (VCL) interaction partners

  1. Results suggest that myosin VI (show MYO6 ELISA Kits) and vinculin form a molecular apparatus that generates cohesive cell-cell contacts in cultured mammalian epithelia.

Vinculin (VCL) Antigen Profile

Antigen Summary

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Alternative names and synonyms associated with Vinculin (VCL)

  • vinculin (VCL) Elisa Kit
  • vinculin (vcl) Elisa Kit
  • vinculin A (vinA) Elisa Kit
  • Vinculin (Vinc) Elisa Kit
  • vinculin (CpipJ_CPIJ013873) Elisa Kit
  • vinculin (LOC100228062) Elisa Kit
  • vinculin (LOC100356093) Elisa Kit
  • vinculin (Vcl) Elisa Kit
  • vinculin (Bm1_37935) Elisa Kit
  • 9430097D22 Elisa Kit
  • AA571387 Elisa Kit
  • AI462105 Elisa Kit
  • AW545629 Elisa Kit
  • CG3299 Elisa Kit
  • CMD1W Elisa Kit
  • CMH15 Elisa Kit
  • CT11081 Elisa Kit
  • DDBDRAFT_0186762 Elisa Kit
  • DDBDRAFT_0232320 Elisa Kit
  • DDB_0186762 Elisa Kit
  • DDB_0232320 Elisa Kit
  • Dmel\\CG3299 Elisa Kit
  • Dmvincp Elisa Kit
  • EG:103B4.1 Elisa Kit
  • hm:zehn2160 Elisa Kit
  • im:6902790 Elisa Kit
  • LOC100228062 Elisa Kit
  • MV Elisa Kit
  • MVCL Elisa Kit
  • VCL Elisa Kit
  • vcl-A Elisa Kit
  • Vin Elisa Kit
  • Vin2EF Elisa Kit
  • vinc Elisa Kit

Protein level used designations for Vinculin (VCL) ELISA Kits

vinculin , CG3299-PA , Vinc-PA , vinculin at 2EF , vinculin-like , metavinculin , vinculin/metavinculin

100064165 Equus caballus
450531 Pan troglodytes
552980 Danio rerio
8625369 Dictyostelium discoideum AX4
31201 Drosophila melanogaster
6047004 Culex quinquefasciatus
100036705 Xenopus (Silurana) tropicalis
100228062 Taeniopygia guttata
100410985 Callithrix jacchus
100476722 Ailuropoda melanoleuca
714312 Macaca mulatta
721921 Macaca mulatta
100075715 Ornithorhynchus anatinus
100583187 Nomascus leucogenys
7414 Homo sapiens
396422 Gallus gallus
100356093 Oryctolagus cuniculus
22330 Mus musculus
305679 Rattus norvegicus
783645 Bos taurus
373770 Xenopus laevis
100302597 Meleagris gallopavo
479252 Canis lupus familiaris
100357160 Oryctolagus cuniculus
396974 Sus scrofa
100722183 Cavia porcellus
101121312 Ovis aries
6102471 Brugia malayi
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