Browse our anti-BTRC (BTRC) Antibodies

Full name:
anti-beta-Transducin Repeat Containing Antibodies (BTRC)
On are 50 beta-Transducin Repeat Containing (BTRC) Antibodies from 12 different suppliers available. Additionally we are shipping BTRC Kits (14) and BTRC Proteins (3) and many more products for this protein. A total of 70 BTRC products are currently listed.
b-TrCP, BETA-TRCP, Beta-Trcp1, betaTrCP, btrc, btrc-a, bTrCP, bTrCP1, Fbw1a, FBXW1, FBXW1A, FWD1, HOS, mKIAA4123, Slimb
list all antibodies Gene Name GeneID UniProt
BTRC 8945 Q9Y297
BTRC 361765  
BTRC 12234 Q3ULA2

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anti-Mouse (Murine) BTRC Antibodies:

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Top referenced anti-BTRC Antibodies

  1. Human Polyclonal BTRC Primary Antibody for EIA, IF - ABIN952275 : Popov, Schülein, Jaenicke, Eilers: Ubiquitylation of the amino terminus of Myc by SCF(β-TrCP) antagonizes SCF(Fbw7)-mediated turnover. in Nature cell biology 2010 (PubMed)
    Show all 4 references for 952275

More Antibodies against BTRC Interaction Partners

Xenopus laevis beta-Transducin Repeat Containing (BTRC) interaction partners

  1. Strong ERK (show MAPK1 Antibodies) activation can target Cdc25A (show CDC25A Antibodies) for degradation in a manner similar to, but independent of, Chk1 (show CHEK1 Antibodies) for cell cycle arrest.

Human beta-Transducin Repeat Containing (BTRC) interaction partners

  1. It has been proposed that CENP-W (show CENPW Antibodies) may function as a booster of beta-TrCP1 nuclear import to increase the oncogenicity of beta-TrCP1.

  2. oncogenic effect of miR (show MLXIP Antibodies)-182 and its reversal by beta-TrCP2 were confirmed in vivo This study suggests that beta-TrCP and miR (show MLXIP Antibodies)-182 may be possible biomarkers and targets for early detection and treatment of pancreatic cancer

  3. Beta-TrCP controls ubiquitination and degradation of liver-enriched transcription factor CREB-H (show CREB3L3 Antibodies).

  4. Phosphorylated VEGFR-2 (show KDR Antibodies) was reduced by hyperglycemia while total VEGFR-2 (show KDR Antibodies) was almost unaltered. However, VEGFR-2 (show KDR Antibodies) was reduced when directly exposed to reactive oxygen species, with resultant co-location of beta-TrCP and VEGFR-2 (show KDR Antibodies).

  5. Low GAS7C increases cancer cell motility by promoting N-WASP (show WASL Antibodies)/FAK (show PTK2 Antibodies)/F-actin cytoskeleton dynamics. It also enhances beta-catenin (show CTNNB1 Antibodies) stability via hnRNP U (show HNRNPU Antibodies)/beta-TrCP complex formation.

  6. EBV-miR (show MLXIP Antibodies)-BART10-3p facilitated epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma by targeting BTRC.

  7. beta-TrCP1/FWD1 dominant negative mutant has a role in reducing myeloma cell growth

  8. This study showed SCF (show KITLG Antibodies)(beta-TRCP) earmarks Set8 (show SETD8 Antibodies) for ubiquitination and degradation in a casein kinase I (show CSNK1D Antibodies)-dependent manner, which is activated by DNA-damaging agents.

  9. SCF (show KITLG Antibodies)(beta-TrCP1/2) interacting partners, were identified.

  10. a model that CD166 (show ALCAM Antibodies) regulates MCAM (show MCAM Antibodies) through a signaling flow from activation of PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) and c-Raf (show RAF1 Antibodies)/MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) signaling to the inhibition of potential MCAM (show MCAM Antibodies) ubiquitin E3 ligases, betaTrCP and Smurf1 (show SMURF1 Antibodies).

Mouse (Murine) beta-Transducin Repeat Containing (BTRC) interaction partners

  1. betaTrCP levels are correlated with imiquimod-induced skin lesion.

  2. beta-TrCP1/FWD1 dominant negative mutant has a role in reducing myeloma cell growth

  3. Erbin (show ERBB2IP Antibodies) as a novel substrate of SAG (show RNF7 Antibodies)-betaTrCP E3 ligase.

  4. these results clearly suggest that both beta-TrCP- and Hrd1 (show SYVN1 Antibodies)-dependent degradation mechanisms regulate the transcriptional activity of Nrf1 (show NRF1 Antibodies) to maintain cellular homeostasis.

  5. beta-TrCP may be an essential player in UVB induced responses in skin

  6. Glycogen synthase kinase 3 (show GSK3a Antibodies) phosphorylates a group of Ser (show SIGLEC1 Antibodies) residues in the Neh6 domain of mouse Nrf2 (show NFE2L2 Antibodies) that overlap with an SCF (show KITLG Antibodies)/beta-TrCP destruction motif (DSGIS, residues 334 to 338) and promotes its degradation in a Keap1 (show KEAP1 Antibodies)-independent manner.

  7. LPS (show TLR4 Antibodies) appears to destabilize the LPCAT1 (show LPCAT1 Antibodies) protein by GSK-3beta (show GSK3b Antibodies)-mediated phosphorylation within a canonical phosphodegron for beta-TrCP docking and site-specific ubiquitination.

  8. the two beta-TrCP paralogs have a nonredundant role in spermatogenesis

  9. anti-inflammatory effects of H(2)O(2) may result from its ability to decrease ubiquitination as well as subsequent degradation of I kappaB alpha through inhibiting the association between I kappaB alpha and SCF (show KITLG Antibodies)(beta-TrCP)

  10. BMP-2 (show BMP2 Antibodies) modulates beta-catenin (show CTNNB1 Antibodies) signaling through stimulation of Lrp5 (show LRP5 Antibodies) expression and inhibition of beta-TrCP expression in osteoblasts

BTRC Antigen Profile

Antigen Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class\; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.

Alternative names and synonyms associated with BTRC

  • beta-transducin repeat containing (BTRC) antibody
  • beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC) antibody
  • beta-transducin repeat containing E3 ubiquitin protein ligase (btrc) antibody
  • beta-transducin repeat containing (btrc) antibody
  • beta-transducin repeat containing E3 ubiquitin protein ligase (Btrc) antibody
  • beta-transducin repeat containing protein (Btrc) antibody
  • b-TrCP antibody
  • BETA-TRCP antibody
  • Beta-Trcp1 antibody
  • betaTrCP antibody
  • btrc antibody
  • btrc-a antibody
  • bTrCP antibody
  • bTrCP1 antibody
  • Fbw1a antibody
  • FBXW1 antibody
  • FBXW1A antibody
  • FWD1 antibody
  • HOS antibody
  • mKIAA4123 antibody
  • Slimb antibody

Protein level used designations for BTRC

beta-transducin repeat containing , beta-transducin repeat containing protein , F-box/WD repeat-containing protein 1A , f-box/WD repeat-containing protein 1A-like , E3RSIkappaB , F-box and WD repeats protein beta-TrCP , F-box and WD-repeat protein 1B , beta-TrCP1 , epididymis tissue protein Li 2a , pIkappaBalpha-E3 receptor subunit , beta-TrCP , beta-transducin repeat-containing protein , SCF b-TRCP , beta-TrCP protein E3RS-IkappaB , mE3RS-IkappaB , pIkappaB-E3 receptor subunit , ubiquitin ligase FWD1

423854 Gallus gallus
450685 Pan troglodytes
486851 Canis lupus familiaris
534072 Bos taurus
549140 Xenopus (Silurana) tropicalis
100171847 Pongo abelii
100337561 Xenopus laevis
100470916 Ailuropoda melanoleuca
100157842 Sus scrofa
100634006 Amphimedon queenslandica
8945 Homo sapiens
361765 Rattus norvegicus
394362 Xenopus laevis
100350519 Oryctolagus cuniculus
100730107 Cavia porcellus
101101939 Ovis aries
12234 Mus musculus
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