Browse our anti-CDC25A (CDC25A) Antibodies

Full name:
anti-Cell Division Cycle 25 Homolog A (S. Pombe) Antibodies (CDC25A)
On are 472 Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) Antibodies from 30 different suppliers available. Additionally we are shipping CDC25A Proteins (12) and CDC25A Kits (10) and many more products for this protein. A total of 540 CDC25A products are currently listed.
cdc25A, CDC25A2, D9Ertd393e, sb:cb317
list all antibodies Gene Name GeneID UniProt
CDC25A 993 P30304
CDC25A 171102 P48965
CDC25A 12530  

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Most Popular Reactivities for anti-CDC25A (CDC25A) Antibodies

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anti-Human CDC25A Antibodies:

anti-Rat (Rattus) CDC25A Antibodies:

anti-Mouse (Murine) CDC25A Antibodies:

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Top referenced anti-CDC25A Antibodies

  1. Human Polyclonal CDC25A Primary Antibody for EIA, IHC (p) - ABIN358093 : Ito, Yoshida, Matsuzuka, Matsuura, Nakamura, Nakamine, Kakudo, Kuma, Miyauchi: Cdc25A and cdc25B expression in malignant lymphoma of the thyroid: correlation with histological subtypes and cell proliferation. in International journal of molecular medicine 2004 (PubMed)
    Show all 6 references for 358093

  2. Human Polyclonal CDC25A Primary Antibody for EIA, IHC (p) - ABIN358098 : Nemoto, Vogt, Oguri, Lazo: Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells. in The Prostate 2003 (PubMed)
    Show all 5 references for 358098

  3. Human Polyclonal CDC25A Primary Antibody for EIA, IHC (p) - ABIN358096 : Goloudina, Yamaguchi, Chervyakova, Appella, Fornace, Bulavin: Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint. in Cell cycle (Georgetown, Tex.) 2003 (PubMed)
    Show all 5 references for 358096

  4. Human Polyclonal CDC25A Primary Antibody for EIA, IHC (p) - ABIN358097 : Chen, Ryan, Piwnica-Worms: Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding. in Molecular and cellular biology 2003 (PubMed)
    Show all 5 references for 358097

  5. Human Polyclonal CDC25A Primary Antibody for IHC (p), WB - ABIN389527 : Chow, Siu, Fung, Chan, Lau, Arooz, Ng, Yamashita, Poon: DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase. in Molecular biology of the cell 2003 (PubMed)
    Show all 3 references for 389527

  6. Human Polyclonal CDC25A Primary Antibody for DB - ABIN389906 : Xu, Yamamoto, Liu, Ito, Ngan, Kondo, Nagano, Dono, Sekimoto, Monden: CDC25A inhibition suppresses the growth and invasion of human hepatocellular carcinoma cells. in International journal of molecular medicine 2008 (PubMed)
    Show all 2 references for 389906

  7. Human Monoclonal CDC25A Primary Antibody for IF, IHC (p) - ABIN115128 : Draetta, Eckstein: Cdc25 protein phosphatases in cell proliferation. in Biochimica et biophysica acta 1997 (PubMed)
    Show all 2 references for 115128

  8. Dog (Canine) Polyclonal CDC25A Primary Antibody for WB - ABIN2792169 : Ray, Kiyokawa: CDC25A phosphatase: a rate-limiting oncogene that determines genomic stability. in Cancer research 2008 (PubMed)

  9. Human Polyclonal CDC25A Primary Antibody for ELISA, WB - ABIN1531550 : Galaktionov, Beach: Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins. in Cell 1992 (PubMed)

More Antibodies against CDC25A Interaction Partners

Zebrafish Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) interaction partners

  1. Stat3 (show STAT3 Antibodies) regulates cell proliferation and axis extension in part via upregulation of Cdc25a expression during oogenesis. Accordingly, restoring Cdc25a expression in stat3 (show STAT3 Antibodies) mutants partially suppressed cell proliferation and gastrulation defects.

Human Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) interaction partners

  1. These results identify a new positive regulatory loop between Cdc25A and its CDK-cyclin substrates which contributes to accelerate entry into mitosis through the regulation of Cdc25A activity in G2.

  2. The expression level of Cdc25A was significantly increased (<0.05) after treatment with miR (show MLXIP Antibodies)-675 mimics.

  3. miR-497 modulates the growth of chondrosarcoma cells by targeting Cdc25A.

  4. This study demonstrated that the cell cycle pathway and the cdc25a gene may be crucial in the pathogenesis and progression of hepatocellular carcinoma.

  5. Increased CDC25A is associated with invasiveness in Non-small Cell Lung Cancer.

  6. Data indicate that nine compounds were identified with Ki values for CDC25A, -B and -C ranging from 0.01 to 4.4 muM.

  7. Identify CDC25A as an early cell cycle transducer of FLT3 (show FLT3 Antibodies)-ITD oncogenic signaling, and as a promising target to inhibit proliferation and re-induce differentiation of FLT3 (show FLT3 Antibodies)-ITD acute myeloid leukemia (show BCL11A Antibodies) cells.

  8. STK38-mediated phosphorylation of CDC25A at Ser-76 and the subsequent degradation of CDC25A are required to promote DNA damage-induced G2/M checkpoint activation.

  9. let-7c suppresses HCC (show FAM126A Antibodies) progression, possibly by directly targeting the cell cycle regulator (show CDKN2A Antibodies) CDC25A and indirectly affecting its downstream target molecules. Let-7c may therefore be an effective therapeutic target for HCC (show FAM126A Antibodies).

  10. Results suggest that miR-449a may act as a tumor suppressor by targeting CDC25A in endometrial cancer.

Mouse (Murine) Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) interaction partners

  1. Our results identify Cdc25A as a potential target for neuroprotectant strategy for the treatment of delayed ischemic neuronal death.

  2. CDC25A-deficient embryonic stem cells resist high doses of ATR inhibitors, which we show is due to their failure to prematurely enter mitosis in response to the drugs.

  3. These results showed that IGF1 (show IGF1 Antibodies) regulated the expression of BOULE (show BOLL Antibodies) and CDC25A mRNAs via ERK1/2 (show MAPK1/3 Antibodies) signaling and in T-independent pathway during spermatogenesis in the adult mouse testes.

  4. accelerated cholangiocyte cystogenesis is likely due to overexpression of Cdc25A

  5. Cdc25A activity is required for the metaphase II arrest in mouse oocytes.

  6. deletion of Cdc25a increased apoptosis and accelerated the elimination of DNA damage following UV

  7. In the DNA damage response, instead of inhibiting cyclin B-CDK1 (show CDK1 Antibodies) through destruction of Cdc25A phosphatase, oocytes utilize an inhibitory phosphorylation of Cdc25B (show CDC25B Antibodies).

  8. Cdc25A inhibitors block cell-cycle progression and proliferation, reduce liver and kidney weights and cyst growth in animal models of polycystic kidney/liver disease.

  9. CDC25A and CDC25B (show CDC25B Antibodies) but not CDC25C (show CDC25C Antibodies) compensate for each other to maintain the proliferative capacity of intestinal epithelial stem and progenitor cells

  10. IL-7 (show IL7 Antibodies) drives Cdc25A-mediated T-cell proliferation, which prevents the nuclear translocation of Foxo1 (show FOXO1 Antibodies), leading to reduced expression of CD62L (show SELL Antibodies) and the migration of T cells into circulation.

Xenopus laevis Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) interaction partners

  1. Cdc25A is a key player in the developmentally regulated program of apoptosis in X. laevis embryos

  2. Strong ERK (show MAPK1 Antibodies) activation can target Cdc25A for degradation in a manner similar to, but independent of, Chk1 (show CHEK1 Antibodies) for cell cycle arrest.

CDC25A Antigen Profile

Antigen Summary

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CDC25A

  • cell division cycle 25 homolog A (S. pombe) (CDC25A) antibody
  • cell division cycle 25A (cdc25a) antibody
  • cell division cycle 25 homolog (cdc25) antibody
  • cell division cycle 25A (CDC25A) antibody
  • cell division cycle 25A (Cdc25a) antibody
  • cdc25A antibody
  • CDC25A2 antibody
  • D9Ertd393e antibody
  • sb:cb317 antibody

Protein level used designations for CDC25A

cell division cycle 25A , cell division cycle 25 homolog A , M-phase inducer phosphatase 1 , Dual specificity phosphatase Cdc25A , CDC25A2-CAG isoform , dual specificity phosphatase CDC25A , dual specificity phosphatase Cdc25A

460341 Pan troglodytes
733851 Xenopus (Silurana) tropicalis
57925 Danio rerio
420375 Gallus gallus
484780 Canis lupus familiaris
520188 Bos taurus
100064223 Equus caballus
993 Homo sapiens
171102 Rattus norvegicus
12530 Mus musculus
734734 Xenopus laevis
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