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Browse our anti-CDC25C (CDC25C) Antibodies

Full name:
anti-Cell Division Cycle 25 Homolog C (S. Pombe) Antibodies (CDC25C)
On www.antibodies-online.com are 275 Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) Antibodies from 26 different suppliers available. Additionally we are shipping CDC25C Proteins (8) and CDC25C Kits (2) and many more products for this protein. A total of 298 CDC25C products are currently listed.
Synonyms:
Cdc25, cdc25-3, CDC25C, PPP1R60, xcdc25-3, xcdc25c
list all antibodies Gene Name GeneID UniProt
CDC25C 995 P30307
CDC25C 12532 P48967
CDC25C 307511  

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Most Popular Reactivities for anti-CDC25C (CDC25C) Antibodies

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anti-Human CDC25C Antibodies:

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anti-Rat (Rattus) CDC25C Antibodies:

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Top referenced anti-CDC25C Antibodies

  1. Human Monoclonal CDC25C Primary Antibody for WB - ABIN393664 : Olson, Wang, Pankratz, Fredericksen, Vachon, Vierkant, Cerhan, Couch: Centrosome-related genes, genetic variation, and risk of breast cancer. in Breast cancer research and treatment 2010 (PubMed)
    Show all 5 references for ABIN393664

  2. Human Monoclonal CDC25C Primary Antibody for BI, WB - ABIN967552 : Peng, Graves, Thoma, Wu, Shaw, Piwnica-Worms: Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 5 references for ABIN967552

  3. Human Polyclonal CDC25C Primary Antibody for IF, IHC (p) - ABIN196818 : Toyoshima-Morimoto, Taniguchi, Nishida: Plk1 promotes nuclear translocation of human Cdc25C during prophase. in EMBO reports 2002 (PubMed)
    Show all 4 references for ABIN196818

  4. Human Polyclonal CDC25C Primary Antibody for IF, IHC (p) - ABIN197346 : Ferguson, White, Donovan, Piwnica-Worms: Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases. in Molecular and cellular biology 2005 (PubMed)
    Show all 3 references for ABIN197346

  5. Human Polyclonal CDC25C Primary Antibody for EIA, WB - ABIN360223 : Varmeh, Manfredi: Overexpression of the dual specificity phosphatase, Cdc25C, confers sensitivity on tumor cells to doxorubicin-induced cell death. in Molecular cancer therapeutics 2008 (PubMed)
    Show all 3 references for ABIN360223

  6. Human Polyclonal CDC25C Primary Antibody for IF (p), IHC (p) - ABIN1387108 : Ghate, Chaudhuri, Sarkar, Sajem, Panja, Rout, Mandal: An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7. in PLoS ONE 2013 (PubMed)
    Show all 2 references for ABIN1387108

  7. Human Monoclonal CDC25C Primary Antibody for WB - ABIN659132 : Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: A Large-scale genetic association study of esophageal adenocarcinoma risk. in Carcinogenesis 2010 (PubMed)
    Show all 2 references for ABIN659132

  8. Human Polyclonal CDC25C Primary Antibody for WB - ABIN2792164 : Bonnet, Mayonove, Morris: Differential phosphorylation of Cdc25C phosphatase in mitosis. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against CDC25C Interaction Partners

Human Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) interaction partners

  1. Data show that TRIB2 (show TRIB2 Antibodies)-mediated degradation of CDC25C is associated with lysine-48-linked CDC25C polyubiquitination driven by the TRIB2 (show TRIB2 Antibodies) kinase-like domain.

  2. the biology of the activation/deactivation of CDC25 (show RASGRF1 Antibodies) by kinases/phosphatases to maintain the level of CDK (show CDK4 Antibodies)-cyclin (show PCNA Antibodies) activities and thus the genomic stability

  3. the knockdown of CDC25C can reduce both the radiotherapy sensitivity and the proliferation activity of EC9706 cells.

  4. results identify CDC25C as a downstream target of the mutated tyrosine kinase (show TXK Antibodies) FLT3 (show FLT3 Antibodies)-ITD affecting cell-cycle regulation in a model of AML (show RUNX1 Antibodies)

  5. Suggest that the p53 (show TP53 Antibodies)-p21 (show CDKN1A Antibodies)-DREAM-CDE/CHR pathway regulates p53 (show TP53 Antibodies)-dependent repression of Survivin (show BIRC5 Antibodies), CDC25C, and PLK1 (show PLK1 Antibodies) in HCT116 cells.

  6. Data indicate that nine compounds were identified with Ki values for CDC25A, -B and -C ranging from 0.01 to 4.4 muM.

  7. These miR (show MLXIP Antibodies)-142-3p functioned as a tumor suppressor by targeting CDC25C.

  8. Cdc25C negatively regulates proapoptotic ASK1 (show MAP3K5 Antibodies) in a cell cycle-dependent manner and may play a role in G2/M checkpoint-mediated apoptosis.

  9. Recurrent CDC25C mutations drive malignant transformation in familial platelet disorder to acute myelogenous leukaemia.

  10. CDC25C seems important for the phenotype of AML (show RUNX1 Antibodies) cells at least for a subset of patients. Many of the identified CDC25 (show RASGRF1 Antibodies) inhibitors show cross-reactivity among the three CDC25 (show RASGRF1 Antibodies) isoforms.

Mouse (Murine) Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) interaction partners

  1. oxidative stress-induced (show SQSTM1 Antibodies) DNA damage of mouse zygotes triggers the cell cycle checkpoint, which results in G2/M cell cycle arrest, and that phospho-Cdc25B (show CDC25B Antibodies) (Ser323), phospho-Cdc25C (Ser216), and phospho-Cdc2 (show CDK1 Antibodies) (Tyr15) participate in activating the G2/M checkpoint.

  2. The role of Cdc25c and Cdc25b (show CDC25B Antibodies) in activating G2/M cell cycle checkpoint in zygote.

  3. an asymmetrical distribution pattern for Cdc25c transcripts in 2-cell embryos.

  4. CDC25A (show CDC25A Antibodies) and CDC25B (show CDC25B Antibodies) but not CDC25C compensate for each other to maintain the proliferative capacity of intestinal epithelial stem and progenitor cells

  5. A single cell cycle genes homology region controls transcription of the cdc25C gene and is able to cooperate with E2F (show E2F1 Antibodies) or Sp1 (show SP1 Antibodies)/3 sites

  6. Cdc25A (show CDC25A Antibodies), or possibly other phosphatases, is able to functionally compensate for the loss of Cdc25B (show CDC25B Antibodies) and Cdc25C in mice

  7. The present study was aimed to investigate the possibility that selenium (Se)-induced oxidative stress mediated alterations in Cdc25c and p21 (show D4S234E Antibodies) may cause modulations in the CDC2 (show CDK1 Antibodies)/Cyclin B1 (show CCNB1 Antibodies) complex responsible for G2/M phase checkpoint in spermatogenesis.

  8. In Lzts1 (show LZTS1 Antibodies)(-/-) mouse embryo fibroblasts (MEFs), Cdc25C degradation was increased during M phase, resulting in decreased Cdk1 (show CDK1 Antibodies) activity.

  9. PP2A:B56delta as a key upstream regulator of Cdk1 (show CDK1 Antibodies) activity upon exit from mitosis

Xenopus laevis Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) interaction partners

  1. Blocking mitotic entry by adding the catalytic subunit of protein kinase A results in increased wee1 Ser549 phosphorylation and maintenance of cdc25C.

  2. These observations identify PP2A (show PPP2R2B Antibodies)/B56delta as a central checkpoint effector and suggest a mechanism for controlling 14-3-3 (show YWHAQ Antibodies) interactions to promote mitosis.

  3. In Xenopus oocytes, p42 MAPK (show MAPK1 Antibodies) interacts with hypophosphorylated Cdc25 before meiotic induction. During meiotic induction, p42 MAPK (show MAPK1 Antibodies) phosphorylates Cdc25 at three sites, increasing Cdc25's phosphatase activity.

CDC25C Antigen Profile

Antigen Summary

This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Alternative names and synonyms associated with CDC25C

  • cell division cycle 25 homolog C (S. pombe) (CDC25C) antibody
  • cell division cycle 25C (cdc25c) antibody
  • cell division cycle 25C (LOC100343637) antibody
  • cell division cycle 25C (CDC25C) antibody
  • cell division cycle 25C (Cdc25c) antibody
  • cell division cycle 25C (cdc25c-a) antibody
  • Cdc25 antibody
  • cdc25-3 antibody
  • CDC25C antibody
  • PPP1R60 antibody
  • xcdc25-3 antibody
  • xcdc25c antibody

Protein level used designations for CDC25C

cell division cycle 25 homolog C (S. pombe) , m-phase inducer phosphatase 3-like , cell division cycle 25 homolog C , cell division cycle 25C , Dual specificity phosphatase Cdc25C , M-phase inducer phosphatase 3 , dual specificity phosphatase Cdc25C , dual specificity phosphatase CDC25C , mitosis inducer CDC25 , phosphotyrosine phosphatase , protein phosphatase 1, regulatory subunit 60 , cell cycle phosphatase CDC25C , cell division cycle control protein 25C

GENE ID SPECIES
714115 Macaca mulatta
100062352 Equus caballus
100451443 Pongo abelii
100124300 Xenopus (Silurana) tropicalis
100343637 Oryctolagus cuniculus
100588617 Nomascus leucogenys
610456 Canis lupus familiaris
507731 Bos taurus
100144474 Sus scrofa
995 Homo sapiens
12532 Mus musculus
307511 Rattus norvegicus
397737 Xenopus laevis
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