Browse our anti-CDK2 (CDK2) Antibodies

Full name:
anti-Cyclin-Dependent Kinase 2 Antibodies (CDK2)
On www.antibodies-online.com are 465 Cyclin-Dependent Kinase 2 (CDK2) Antibodies from 34 different suppliers available. Additionally we are shipping CDK2 Kits (41) and CDK2 Proteins (34) and many more products for this protein. A total of 580 CDK2 products are currently listed.
Synonyms:
A630093N05Rik, cdk2L, CDKN2, CINP, eg1, MGC84068, p33(CDK2), wu:fa10c02, zgc:56598, zgc:77684
list all antibodies Gene Name GeneID UniProt
CDK2 362817  
CDK2 1017 P24941
CDK2 12566 P97377

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Most Popular Reactivities for anti-CDK2 (CDK2) Antibodies

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Top referenced anti-CDK2 Antibodies

  1. Human Polyclonal CDK2 Primary Antibody for EIA, WB - ABIN358106 : Bicaku, Patel, Acevedo-Duncan: Cyclin-dependent kinase activating kinase/Cdk7 co-localizes with PKC-iota in human glioma cells. in Tissue & cell 2005 (PubMed)
    Show all 5 references for 358106

  2. Dog (Canine) Monoclonal CDK2 Primary Antibody for BI, IP - ABIN967776 : Hinds, Mittnacht, Dulic, Arnold, Reed, Weinberg: Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. in Cell 1992 (PubMed)
    Show all 5 references for 967776

  3. Human Polyclonal CDK2 Primary Antibody for FACS, IHC (p) - ABIN391746 : Moshinsky, Bellamacina, Boisvert, Huang, Hui, Jancarik, Kim, Rice: SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 5 references for 391746

  4. Human Monoclonal CDK2 Primary Antibody for WB - ABIN1106646 : Luo, Zhang, Dastvan, Yanagawa, Reidy, Zhang, Yang, Wilson, McManus: Ubiquitin-dependent proteolysis of cyclin D1 is associated with coxsackievirus-induced cell growth arrest. in Journal of virology 2002 (PubMed)
    Show all 4 references for 1106646

  5. Human Polyclonal CDK2 Primary Antibody for EIA - ABIN358539 : Elledge, Spottswood: A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1. in The EMBO journal 1991 (PubMed)
    Show all 4 references for 358539

  6. Human Polyclonal CDK2 Primary Antibody for DB - ABIN389996 : Tsai, Harlow, Meyerson: Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase. in Nature 1991 (PubMed)
    Show all 4 references for 389996

  7. Human Polyclonal CDK2 Primary Antibody for WB - ABIN389540 : Kino, Tsukamoto, Chrousos: Transcription factor TFIIH components enhance the GR coactivator activity but not the cell cycle-arresting activity of the human immunodeficiency virus type-1 protein Vpr. in Biochemical and biophysical research communications 2002 (PubMed)
    Show all 3 references for 389540

  8. Human Polyclonal CDK2 Primary Antibody for EIA, IHC (p) - ABIN359658 : Chow, Siu, Ho, Ma, Ho, Poon: Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for 359658

  9. Human Polyclonal CDK2 Primary Antibody for IF, ELISA - ABIN1533672 : Gray, Wodicka, Thunnissen, Norman, Kwon, Espinoza, Morgan, Barnes, LeClerc, Meijer, Kim, Lockhart, Schultz: Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. in Science (New York, N.Y.) 1998 (PubMed)

More Antibodies against CDK2 Interaction Partners

Xenopus laevis Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. evidence that cyclin A1 (show CCNA1 Antibodies)-associated activity is a mediator of apoptosis and that cyclin A1 (show CCNA1 Antibodies)/Cdk2 is sufficient to induce apoptosis

Human Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. Here, we found that centrosomal protein of 76 kDa (Cep76 (show Cep76 Antibodies)), previously shown to restrain centriole amplification, interacts with cyclin-dependent kinase 2 (CDK2) and is a bona fide substrate of this kinase. Cep76 (show Cep76 Antibodies) is preferentially phosphorylated by cyclin A (show CCNA2 Antibodies)/CDK2 at a single site S83, and this event is crucial to suppress centriole amplification in S phase

  2. The authors find that Spy1 (show SPDYA Antibodies) confers structural changes to Cdk2 that obviate the requirement of Cdk (show CDK4 Antibodies) activation loop phosphorylation.

  3. CDK2 serves as an important nexus linking primary beta-cell dysfunction to progressive beta-cell mass deterioration in diabetes

  4. Date show that when Wee1 (show WEE1 Antibodies) alone is inhibited, Chk1 (show CHEK1 Antibodies) suppresses CDC45 (show CDC45 Antibodies) loading and thereby limits the extent of unscheduled replication initiation and subsequent S-phase DNA damage, despite very high CDK (show CDK4 Antibodies)-activity.

  5. Results show that cyclin E1 (show CCNE1 Antibodies) and CDK2 participate in STC1 (show STC1 Antibodies) promoting cell proliferation of prostate neoplasm cells.

  6. The data presented here suggest that the temporal separation of pro- and anti-apoptotic pathways by selective inhibition of CDK2 disrupts coherent signaling modules and may synergize with anti-proliferative drugs, averting toxic side effects from CDK1 (show CDK1 Antibodies) inhibition.

  7. periodic phosphorylation of Ku70 (show XRCC6 Antibodies) by cyclin-cyclin (show PCNA Antibodies) dependent kinases prevents the interaction of Ku with replication origin after initiation events in S-phase.

  8. a SUMO-deficient Rb mutant results in reduced SUMOylation and phosphorylation, weakened CDK2 binding, and attenuated E2F-1 (show E2F1 Antibodies) sequestration.

  9. These two states are separated by different metastable states that share hybrid structural features with both forms of the kinase. In contrast, the CDK2/ANS complex landscape is compatible with a conformational selection picture where the binding of ANS in proximity of the alphaC helix causes a population shift toward the inactive conformation

  10. Dsg2 (show DSG2 Antibodies) knockdown arrests non-small cell lung cancer cell cycle progression via modulation of p27 (show PAK2 Antibodies)-CDK2 levels.

Mouse (Murine) Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. CDK2 serves as an important nexus linking primary beta-cell dysfunction to progressive beta-cell mass deterioration in diabetes

  2. data indicate that the essential meiotic functions of Cdk2 depend on its kinase activity, without which the generation of haploid cells is disrupted, resulting in sterility of otherwise healthy animals

  3. Testosterone is the positive regulator of hepatocyte cell cycle via cyclin E (show CCNE1 Antibodies)/cdk2 promoting hepatocarcinogenesis.

  4. This approach allowed us to determine the identity of cyclin E (show CCNE1 Antibodies) protein partners, as well as phosphorylation substrates of cyclins E (cyclin (show PCNA Antibodies) E1and cyclin E2 (show CCNE2 Antibodies))and its associated kinase, Cdk2, in different mouse organs.

  5. RingoA (show SPDYA Antibodies) is an important activator of Cdk2 at meiotic telomeres.

  6. Foxo3 (show FOXO3 Antibodies) circular RNA retards cell cycle progression via forming ternary complexes with p21 (show D4S234E Antibodies) and CDK2.

  7. Results identify phosphorylation of CDK2 at tyrosine 160 as a gate-keeping mechanism for hepatocyte proliferation.

  8. Sox2 (show SOX2 Antibodies) phosphorylation by Cdk2 promotes the establishment but not the maintenance of the pluripotent state.

  9. Our data indicate that Cdk2 and Cdk4 (show CDK4 Antibodies) play important overlapping roles in homeostatic and stress hematopoiesis, which need to be considered when using broad-spectrum cyclin-dependent kinase (show CDK1 Antibodies) inhibitors for cancer therapy.

  10. ablation of the kinase CDK2 alters the nuclear envelope in mouse spermatocytes, and that the proteins SUN1, KASH5 (also known as CCDC155) and lamin C2 show an abnormal cap-like distribution facing the centrosome.

Zebrafish Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (show CDK1 Antibodies), wee1 (show WEE1 Antibodies), p21 (show CDKN1A Antibodies), PCNA (show PCNA Antibodies) and cdk2, but only weakly influences cyclin B1 (show CCNB1 Antibodies), cyclin B2 (show CCNB2 Antibodies) and cyclin E1 (show CCNE1 Antibodies) expression.

  2. PI3-kinase (show PIK3CA Antibodies) and Akt (show AKT1 Antibodies) participate in insulin (show INS Antibodies) stimulation of p34cdc2 (show CDK1 Antibodies) activation in zebrafish oocyte with phosphodiesterase 3 as a potential downstream target.

  3. an essential role for UHRF1 (show UHRF1 Antibodies) phosphorylation by cyclin-dependent kinase 2/cyclin A2 (show CCNA2 Antibodies) during early vertebrate development

Cow (Bovine) Cyclin-Dependent Kinase 2 (CDK2) interaction partners

  1. cyclin D1 (show CCND1 Antibodies), CDK2 and CDK4 (show CDK4 Antibodies) are expressed in both caruncular and intercaruncular cells derived from both nonpregnant, and artificially inseminated cows on days 30 and 60 of gestation

CDK2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

Alternative names and synonyms associated with CDK2

  • MGC84068 protein (MGC84068) antibody
  • cyclin-dependent kinase 2 interacting protein (CINP) antibody
  • Cyclin-dependent kinase 2-interacting protein (cinp) antibody
  • cyclin dependent kinase 2 (Cdk2) antibody
  • cyclin-dependent kinase 2 (CDK2) antibody
  • cyclin-dependent kinase 2 (Cdk2) antibody
  • cyclin-dependent kinase 2 (cdk2) antibody
  • cyclin-dependent kinase 2 (CDK2) (Cdk2) antibody
  • cyclin-dependent kinase-2 alpha (LOC100154715) antibody
  • A630093N05Rik antibody
  • cdk2L antibody
  • CDKN2 antibody
  • CINP antibody
  • eg1 antibody
  • MGC84068 antibody
  • p33(CDK2) antibody
  • wu:fa10c02 antibody
  • zgc:56598 antibody
  • zgc:77684 antibody

Protein level used designations for CDK2

MGC84068 protein , Cyclin-dependent kinase 2-interacting protein , cyclin-dependent kinase 2 interacting protein , cyclin-dependent kinase 2-interacting protein , cell division protein kinase 2 , cyclin dependent kinase 2-alpha , cyclin-dependent kinase 2 , cdc2-related protein kinase , cell devision kinase 2 , p33 protein kinase , CDC2 homolog Eg1 protein kinase , Cell division protein kinase 2

GENE ID SPECIES
444599 Xenopus laevis
744050 Pan troglodytes
100196126 Salmo salar
362817 Rattus norvegicus
1017 Homo sapiens
12566 Mus musculus
406715 Danio rerio
399314 Xenopus laevis
100529062 Gallus gallus
606931 Canis lupus familiaris
519217 Bos taurus
100134865 Oryctolagus cuniculus
100127490 Sus scrofa
100714324 Cavia porcellus
100860751 Capra hircus
100216433 Ovis aries
101844411 Mesocricetus auratus
100689039 Cricetulus griseus
100154715 Sus scrofa
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