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Browse our CDK7 Proteins (CDK7)

Full name:
Cyclin-Dependent Kinase 7 Proteins (CDK7)
On are 13 Cyclin-Dependent Kinase 7 (CDK7) Proteins from 7 different suppliers available. Additionally we are shipping CDK7 Antibodies (200) and CDK7 Kits (38) and many more products for this protein. A total of 270 CDK7 products are currently listed.
AI323415, AI528512, C-MOS, C230069N13, CAK1, CD 7, cdk-7, cdk7, Cdkn7, CG3319, Crk4, dCdk7, Dmcdk7, Dmel\\CG3319, DmMo15, HCAK, MO15, p39MO15, p40MO15, p40[MO15], STK1, zgc:85821
list all proteins Gene Name GeneID UniProt
CDK7 1022 P50613
CDK7 171150  
CDK7 12572 Q03147

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CDK7 Proteins (CDK7) by Origin

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More Proteins for CDK7 Interaction Partners

Fruit Fly (Drosophila melanogaster) Cyclin-Dependent Kinase 7 (CDK7) interaction partners

  1. CDK7 is required for the mitochondrial localization of Hid and induction of apoptosis.

  2. The multitask protein Xpd (show ERCC2 Proteins) also plays an essential role in cell cycle regulation that appears to be independent of transcription or nucleotide excision repair.

  3. Cdk7 is required for full activation of Drosophila heat-shock genes and RNA polymerase II phosphorylation in vivo.

Human Cyclin-Dependent Kinase 7 (CDK7) interaction partners

  1. Cdk7 broadly influences transcription and capping.

  2. Our results indicated that CCNH (show CCNH Proteins)/CDK7-CtBP2 (show CTBP2 Proteins) axis may augment ESCC cell migration, and targeting the interaction of both may provide a novel therapeutic target of esophageal squamous cell carcinoma .

  3. Study shows that triple-negative but not hormone receptor (show NR4A1 Proteins)-positive breast cancer cells are exceptionally dependent on CDK7, a transcriptional cyclin-dependent kinase (show CDK1 Proteins).

  4. Data suggest a quantitative contribution of CDK7 to mRNA synthesis, which is critical for cellular homeostasis.

  5. Data indicate that TG02 blocked signaling by CDKs 1, 2, 7, and 9 and ERK5 (show MAPK7 Proteins), leading to potent and highly consistent antimyeloma activity.

  6. CDK7 involved in phosphorylation/activation of CDK4 (show CDK4 Proteins) and CDK6 (show CDK6 Proteins); existence of CDK4 (show CDK4 Proteins)-activating kinase(s) other than CDK7; and novel CDK7-dependent positive feedbacks mediated by p21 (show CDKN1A Proteins) phosphorylation by CDK4 (show CDK4 Proteins) and CDK2 (show CDK2 Proteins) to sustain CDK4 (show CDK4 Proteins) activation.

  7. CCNH (show CCNH Proteins) and CDK7 may play an important role in the tumorigenesis and development of esophageal squamous cell carcinoma.

  8. Activating phosphorylation of Cdk7 rises concurrently with that of Cdk4 (show CDK4 Proteins) as cells exit quiescence and accelerates Cdk4 (show CDK4 Proteins) activation in vitro.

  9. Interaction with cyclin H (show CCNH Proteins)/cyclin-dependent kinase 7 (CCNH (show CCNH Proteins)/CDK7) stabilizes C-terminal binding protein 2 (CtBP2 (show CTBP2 Proteins)) and promotes cancer cell migration

  10. three CTD kinases, CDK7, CDK9 (show CDK9 Proteins), and BRD4 (show BRD4 Proteins), engage in cross-talk, modulating their subsequent C-terminal domain phosphorylation, and also phosphorylate TAF7 (show TAF7 Proteins)

Mouse (Murine) Cyclin-Dependent Kinase 7 (CDK7) interaction partners

  1. Whereas Cdk7 was completely dispensable for global transcription, it was essential for the cell cycle via phosphorylation of Cdk1 (show CDK1 Proteins) and Cdk2 (show CDK2 Proteins). In vivo, Cdk7 was indispensable for cell proliferation except during the first stages of embryonic development.

  2. investigated the function of the Cdk7.cyclin (show PCNA Proteins) H.Mat1 complex in murine embryonic stem (ES) cells and preimplantation embryos to determine whether it regulates the unique cell cycle structure and transcriptional network of pluripotent cells

  3. Cdk7 kinase activity and cell cycle kinetics were found to be comparable in wild-type and Hint(-/-) mouse embryonic fibroblasts, suggesting that Hint may not be a key regulator of Cdk7 activity

  4. results demonstrate that the Cdk7 submodule of transcription factor IIH acts as a physiological roadblock to adipogenesis by inhibiting PPARgamma (show PPARG Proteins) activity

  5. Inhibition of SF-1 (show SF1 Proteins)-mediated transcription by SUMOylation in adrenocortical cancer cells is mediated through reduced CDK7-induced phosphorylation of SF-1 (show SF1 Proteins).

Pig (Porcine) Cyclin-Dependent Kinase 7 (CDK7) interaction partners

  1. CDK7 and CCNH (show CCNH Proteins) activate CDC2 (show CDK1 Proteins) by T161 phosphorylation and make up CDK-activating kinase, which is required for normal meiotic progression during porcine oocyte maturation.

Cow (Bovine) Cyclin-Dependent Kinase 7 (CDK7) interaction partners

  1. The present results suggest that demecolcine might contribute to the activation of the Mos (show MOCOS Proteins)/MAPK (show MAPK1 Proteins) pathway and affect spindle structure

Zebrafish Cyclin-Dependent Kinase 7 (CDK7) interaction partners

  1. Analysis of Cdk7 expression in unfertilized eggs, embryos and organs of adult zebrafish suggests that Cdk7 message is maternally loaded; its transcript is detected throughout early embryonic development.

CDK7 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Alternative names and synonyms associated with CDK7

  • Cyclin-dependent kinase 7 (Cdk7)
  • cyclin-dependent kinase 7 (cdk7)
  • cyclin-dependent kinase 7 (CDK7)
  • cyclin-dependent kinase 7 (Cdk7)
  • cyclin-dependent kinase 7 (LOC100358882)
  • v-mos Moloney murine sarcoma viral oncogene homolog (MOS)
  • AI323415 protein
  • AI528512 protein
  • C-MOS protein
  • C230069N13 protein
  • CAK1 protein
  • CD 7 protein
  • cdk-7 protein
  • cdk7 protein
  • Cdkn7 protein
  • CG3319 protein
  • Crk4 protein
  • dCdk7 protein
  • Dmcdk7 protein
  • Dmel\\CG3319 protein
  • DmMo15 protein
  • HCAK protein
  • MO15 protein
  • p39MO15 protein
  • p40MO15 protein
  • p40[MO15] protein
  • STK1 protein
  • zgc:85821 protein

Protein level used designations for CDK7

CG3319-PA , Cdk7-PA , Mo15 , cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) , cyclin-dependent kinase 7 (MO15, cdk-activating kinase) , 39 KDa protein kinase , CAK , CDK-activating kinase 1 , TFIIH basal transcription factor complex kinase subunit , cell division protein kinase 7 , homolog of Xenopus MO15 Cdk-activating kinase , kinase subunit of CAK , p39 Mo15 , protein kinase , serine/threonine kinase stk1 , serine/threonine protein kinase 1 , serine/threonine protein kinase MO15 , serine/threonine-protein kinase 1 , 39 protein kinase , P39 Mo15 , cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase) , cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) , 39 kDa protein kinase , CDK-activating kinase , CR4 protein kinase , CRK4 PK (CDC2-related-kinase-4 protein kinase) , protein-tyrosine kinase MPK-7 , 40 kDa protein kinase , CDC2/CDK2,4-activating kinase , P40 MO15 , cell division protein kinase 7-like protein , Moloney murine sarcoma viral (v-mos) oncogene homolog , oocyte maturation factor Mos

31441 Drosophila melanogaster
549973 Xenopus (Silurana) tropicalis
1022 Homo sapiens
171150 Rattus norvegicus
12572 Mus musculus
608441 Canis lupus familiaris
100310797 Sus scrofa
515462 Bos taurus
405897 Danio rerio
100725955 Cavia porcellus
771294 Gallus gallus
101119934 Ovis aries
399461 Xenopus laevis
100358882 Oryctolagus cuniculus
100049964 Equus caballus
444869 Bos taurus
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