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Browse our anti-CDKN2C (CDKN2C) Antibodies

Full name:
anti-Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) Antibodies (CDKN2C)
On www.antibodies-online.com are 95 Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C) Antibodies from 19 different suppliers available. Additionally we are shipping CDKN2C Proteins (10) and CDKN2C Kits (3) and many more products for this protein. A total of 114 CDKN2C products are currently listed.
Synonyms:
C77269, CDKN2C, INK4c, INK4d, p18, p18-INK4C, p18INK4c
list all antibodies Gene Name GeneID UniProt
CDKN2C 1031 P42773
CDKN2C 12580 Q60772
CDKN2C 54238  

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Most Popular Reactivities for anti-CDKN2C (CDKN2C) Antibodies

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anti-Human CDKN2C Antibodies:

anti-Mouse (Murine) CDKN2C Antibodies:

anti-Rat (Rattus) CDKN2C Antibodies:

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Top referenced anti-CDKN2C Antibodies

  1. Human Monoclonal CDKN2C Primary Antibody for IHC (p), IP - ABIN487307 : Thullberg, Welcker, Bartkova, Kjerulff, Lukas, Högberg, Bartek: Monoclonal antibody probes for p21WAF1/CIP1 and the INK4 family of cyclin-dependent kinase inhibitors. in Hybridoma 2000 (PubMed)

More Antibodies against CDKN2C Interaction Partners

Human Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C) interaction partners

  1. DNA methyltransferase 3A (show DNMT3A Antibodies) promotes cell proliferation by silencing CDK (show CDK4 Antibodies) inhibitor p18INK4C in gastric carcinogenesis

  2. Data suggest that cell cycle-dependent kinase inhibitors CDKN2C/p18 and CDKN1A/p21 (show CDKN1A Antibodies) facilitate cell cycle entry/cell proliferation of quiescent adult human pancreatic beta cells in primary culture (from tissues obtained from organ donors).

  3. this studydemonstrated abundant levels of the critical negative cell-cycle regulators, p27(Kip1 (show CDKN1B Antibodies)), its phosphorylated form, p-p27 (show PAK2 Antibodies)(S10 (show L1CAM Antibodies)), p18Ink4c, and GSK-3 (show GSK3b Antibodies), in beta-cells of both adult human and mouse pancreatic islets, which contribute to maintenance of beta-cell quiescence.

  4. in 85 sporadic parathyroid adenomas, study identified alterations in 5 adenomas: 2 contained heterozygous changes in CDKN1A, 1 germline and 1 of undetermined germline status; 1 had a CDKN2B (show CDKN2B Antibodies) germline alteration, accompanied by loss of the normal allele in the tumor (LOH); 2 had variants of CDKN2C, 1 somatic and 1 germline with LOH

  5. Mutations in CDKN2C is associated with sporadic parathyroid adenoma.

  6. Analysis of B1a lymphocyte phenotypes of p18-deficient C57BL/6 mice finds that p18 is a key regulator of the size of the B1a cell pool.

  7. up-regulated HULC promotes proliferation of hepatoma cells through suppressing p18

  8. Data indicate that the role of CDKN2C in the adverse outcome of cases with hemizygous deletion was less certain.

  9. Expression of p15 (show CDKN2B Antibodies), p18 and p27 (show PAK2 Antibodies) was not generally related to the MEN1 (show MEN1 Antibodies) gene mutational status of the investigated 18 pancreatic endocrine tumours.

  10. propose that the contrasting behavior of the two very similar INK4 (show CDKN2A Antibodies) proteins could reflect their respective roles in senescence versus differentiation

Mouse (Murine) Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C) interaction partners

  1. CD4 (show CD4 Antibodies)+ T cells from mice genetically deficient for p18ink4c divide more rapidly than wild-type cells in response to antigenic, costimulatory and growth factor signals.

  2. p18 represents a potent and specific target for enhancing the self-renewal property of HSC (show FUT1 Antibodies), as demonstrated the effect of inhibitors

  3. p18 may play protective roles and may be associated with or partially account for the cytoprotective effects of HO-1 (show HMOX1 Antibodies) in cisplatin-induced acute kidney injury.

  4. Cdk4 (show CDK4 Antibodies) and Cdk6 (show CDK6 Antibodies) cooperate in hematopoietic tumor development and suggest a role for Cdk6 (show CDK6 Antibodies) in sequestering INK4 (show CDKN2A Antibodies) proteins away from Cdk4 (show CDK4 Antibodies).

  5. Gata3 (show GATA3 Antibodies)/Ruvbl2 (show RUVBL2 Antibodies) complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression.

  6. deletion of P18 results in a deacreased proliferation of hematopoietic progenitor cells (HPCs) suggesting a positive role for P18 on HPCs in vivo

  7. A p18 -74 C/T mutation is the leading causal variant for the cell expansion that characterizes NZB and NZM2410 lupus-prone mouse strains.

  8. This study demonstrated the predominant expression MEN1 (show MEN1 Antibodies)-related genes, particularly MLL (show MLL Antibodies) and p27 (show CDKN1B Antibodies), in the endocrine organs, and a tissue-specific haploinsuffiency of MLL (show MLL Antibodies) may lead to a decrease in levels of p27 (show CDKN1B Antibodies) and p18 mRNAs in endocrine organs.

  9. Cdkn2c plays a critical role in B1a cell self-renewal and its impaired expression leads to an accumulation of these cells with high autoreactive potential.

  10. define the first physiologic function for Noxa (show PMAIP1 Antibodies) and suggest that by repressing Noxa (show PMAIP1 Antibodies), induction of G arrest by p18INK4c bypasses a homeostatic cell-cycle checkpoint in intermediate plasma cells (iPCs) for PC differentiation

CDKN2C Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.

Alternative names and synonyms associated with CDKN2C

  • cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C) antibody
  • cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (cdkn2c) antibody
  • cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (Cdkn2c) antibody
  • C77269 antibody
  • CDKN2C antibody
  • INK4c antibody
  • INK4d antibody
  • p18 antibody
  • p18-INK4C antibody
  • p18INK4c antibody

Protein level used designations for CDKN2C

cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) , cyclin-dependent kinase 4 inhibitor C , CDK6 inhibitor p18 , cyclin-dependent inhibitor , cyclin-dependent kinase 6 inhibitor p18 , p18-INK6 , cyclin-dependent kinase 6 inhibitor , p18-INK4c

GENE ID SPECIES
429104 Gallus gallus
469319 Pan troglodytes
505691 Bos taurus
711877 Macaca mulatta
100144705 Xenopus (Silurana) tropicalis
1031 Homo sapiens
12580 Mus musculus
475359 Canis lupus familiaris
54238 Rattus norvegicus
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