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Browse our CDKN2D Proteins (CDKN2D)

Full name:
Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) Proteins (CDKN2D)
On are 7 Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D) Proteins from 6 different suppliers available. Additionally we are shipping CDKN2D Antibodies (65) and many more products for this protein. A total of 79 CDKN2D products are currently listed.
ank2, CDKN2D, INK4d, p19, p19-INK4D, p19INK4d
list all proteins Gene Name GeneID UniProt
CDKN2D 1032 P55273
CDKN2D 12581 Q60773
Rat CDKN2D CDKN2D 494444  

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CDKN2D Proteins (CDKN2D) by Origin

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More Proteins for CDKN2D Interaction Partners

Human Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D) interaction partners

  1. MiR (show MLXIP Proteins)-451 inhibited the proliferation of esophageal squamous cell carcinoma cells by targeting CDKN2D and MAP3K1 (show MAP3K1 Proteins) expression.

  2. Data indicate that upon oxidative DNA damage, cyclin-dependent kinase (show CDK1 Proteins) inhibitor p19INK4d strongly binds to and relaxes chromatin.

  3. CDKN2D repression by PML (show PML Proteins)/RARalpha (show RARA Proteins) disrupts both cell proliferation and differentiation in the pathogenesis of acute promyelocytic leukemia (show PML Proteins).

  4. p19-INK4d inhibits neuroblastoma (show ARHGEF16 Proteins) cell growth, induces differentiation and is hypermethylated and downregulated in MYCN (show MYCN Proteins)-amplified neuroblastomas.

  5. CDKN2D-WDFY2 (show ZFYVE22 Proteins) fusion could be an important molecular signature for understanding and classifying sub-lineages among heterogeneous high-grade serous ovarian carcinomas.

  6. Mutations in CDKN2D is associated with sporadic parathyroid adenoma.

  7. P19(INK4d) expression is a poor prognostic factor in ovarian cancer patients.

  8. PTB (show PTBP1 Proteins) plays as a negative regulator in H1299 cell proliferation at least by inducing p19(Ink4d) expression at transcriptional and post-transcriptional levels.

  9. Up-regulation of CDKN2D during in-vitro passages of human amniotic fluid-derived mesenchymal stromal cells may indicate the begging of early senescence process in a p53 (show TP53 Proteins)-independent mechanism.

  10. E2F1 (show E2F1 Proteins) is involved in the induction of p19INK4d following UV irradiation

Mouse (Murine) Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D) interaction partners

  1. p19 INK4d controls hematopoietic stem cells in a cell-autonomous manner during genotoxic stress and through the microenvironment during aging

  2. Cdk4 (show CDK4 Proteins) and Cdk6 (show CDK6 Proteins) cooperate in hematopoietic tumor development and suggest a role for Cdk6 (show CDK6 Proteins) in sequestering INK4 proteins away from Cdk4 (show CDK4 Proteins).

  3. Deletion of p19(Ink4d) (p19), a cyclin-dependent kinase (show CDK1 Proteins) CDK (show CDK4 Proteins) inhibitor gene, in mice results in spontaneous development of tumors in multiple organs and tissues.

  4. We propose that p19INK4d participates in the cellular mechanisms that trigger senescence by contributing to chromatin compaction

  5. CDK5 (show CDK5 Proteins)-mediated phosphorylation of p19INK4d avoids DNA damage-induced neurodegeneration in mouse hippocampus and prevents loss of cognitive functions.

  6. an asymmetrical distribution pattern for Cdkn2d transcripts in 2-cell embryos.

  7. Ectopic expression of RUVBL2 decreases the levels of ARF, whereas knockdown of RUVBL2 results in a marked increase in ARF levels. In addition, RUVBL2 down-regulates the levels of p53 in an ARF-dependent manner.

  8. DeltaNp63alpha has oncogenic activity and its overexpression in human squamous cell carcinomas contributes to the malignant phenotype, and implicate its ability to regulate p16(ink4a)/p19(arf) in the process.

  9. A significant proportion of immortalised cell cultures apparently had neither a p53 mutation nor loss of p19/ARF.

  10. The cyclin-dependent kinase (show CDK1 Proteins) inhibitors p19(Ink4d) and p27(Kip1 (show CDKN1B Proteins)) are coexpressed in select retinal cells and act cooperatively to control cell cycle exit.

CDKN2D Protein Profile

Protein Summary

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Alternative names and synonyms associated with CDKN2D

  • cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) (cdkn2d)
  • cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) (CDKN2D)
  • Cyclin-dependent kinase 4 inhibitor D (cdn2d)
  • cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) (Cdkn2d)
  • similar to cyclin-dependent kinase inhibitor 2D (Cdkn2d)
  • ank2 protein
  • CDKN2D protein
  • INK4d protein
  • p19 protein
  • p19-INK4D protein
  • p19INK4d protein

Protein level used designations for CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) , cyclin-dependent kinase 4 inhibitor D , Cyclin-dependent kinase 4 inhibitor D , CDK inhibitor p19INK4d , cell cycle inhibitor, Nur77 associating protein , cyclin-dependent kinase 4 inhibitor D p19 , inhibitor of cyclin-dependent kinase 4d , p19-INK4d

446719 Xenopus laevis
611216 Canis lupus familiaris
713172 Macaca mulatta
745942 Pan troglodytes
780300 Xenopus (Silurana) tropicalis
100196083 Salmo salar
1032 Homo sapiens
12581 Mus musculus
510244 Bos taurus
494444 Rattus norvegicus
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