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Browse our COPS6 (COPS6) ELISA Kits

Full name:
COP9 Constitutive Photomorphogenic Homolog Subunit 6 (Arabidopsis) ELISA Kits (COPS6)
On www.antibodies-online.com are 0 COP9 Constitutive Photomorphogenic Homolog Subunit 6 (Arabidopsis) (COPS6) ELISA Kits from different suppliers available. Additionally we are shipping COPS6 Antibodies (37) and COPS6 Proteins (11) and many more products for this protein. A total of 52 COPS6 products are currently listed.
Synonyms:
CG6932, CH6, CSN6, Dch6, Dmel\\CG6932, MOV34-34KD, Sgn3, VIP/MOV34, zgc:112075
list all ELISA KIts Gene Name GeneID UniProt
Rat COPS6 COPS6 304343  
Mouse COPS6 COPS6 26893 O88545
Human COPS6 COPS6 10980 Q7L5N1

Show all synonyms

More ELISA Kits for COPS6 Interaction Partners

Fruit Fly (Drosophila melanogaster) COP9 Constitutive Photomorphogenic Homolog Subunit 6 (Arabidopsis) (COPS6) interaction partners

  1. the 2.5A crystal structure of MPN (show PRSS27 ELISA Kits) domain from Drosophila melanogaster CSN6.

Zebrafish COP9 Constitutive Photomorphogenic Homolog Subunit 6 (Arabidopsis) (COPS6) interaction partners

  1. Findings indicate that cops6 plays an anti-apoptotic role during segmentation.

Mouse (Murine) COP9 Constitutive Photomorphogenic Homolog Subunit 6 (Arabidopsis) (COPS6) interaction partners

  1. results define a mechanism for the regulation of Myc (show MYC ELISA Kits) stability through the CSN-Cullin-Fbxw7 (show FBXW7 ELISA Kits) axis and provide insights into the correlation of CSN6 overexpression with Myc (show MYC ELISA Kits) stabilization/activation during tumorigenesis

  2. loss of CSN6 enhances p53 (show TP53 ELISA Kits)-mediated tumor suppression in vivo and CSN6 plays an important role in regulating DNA damage-associated apoptosis and tumorigenesis through control of the MDM2 (show MDM2 ELISA Kits)-p53 (show TP53 ELISA Kits) signaling pathway

Human COP9 Constitutive Photomorphogenic Homolog Subunit 6 (Arabidopsis) (COPS6) interaction partners

  1. CSN6 positively regulates c-Jun (show JUN ELISA Kits) in a MEKK1 (show MAP3K1 ELISA Kits)-dependent manner

  2. our results indicate that CSN6 is a positive regulator of E6AP (show ube3a ELISA Kits) and is important for cervical cancer development.

  3. CSN6 interacts with p27(Kip1 (show CDKN1B ELISA Kits)) and facilitates ubiquitin-mediated degradation of p27(Kip1 (show CDKN1B ELISA Kits)).

  4. Findings indicate that the deregulation of beta-catenin (show CTNNB1 ELISA Kits) by extracellular signal-regulated kinase 2 (ERK2 (show MAPK1 ELISA Kits))-activated CSN6 protein is important for colorectal cancer (CRC (show CALR ELISA Kits)) development.

  5. Analyses of the pseudo metal-binding motif in CSN6 suggest that the loss of two key histidine residues may contribute to the lack of catalytic activity in CSN6.

  6. Data suggest that CSN6 is an important negative regulator of p57 (Kip2 (show CDKN1C ELISA Kits)) , and that overexpression of CSN6 in many types of cancer could lead to decreased expression of p57 (Kip2 (show CDKN1C ELISA Kits)) and result in promoted cancer cell growth.

  7. COPS6 is a target gene of the BACH1 (show BACH1 ELISA Kits) transcription factor according to ChIP-seq analysis in HEK (show EPHA3 ELISA Kits) 293 cells.

  8. loss of CSN6 enhances p53 (show TP53 ELISA Kits)-mediated tumor suppression in vivo and CSN6 plays an important role in regulating DNA damage-associated apoptosis and tumorigenesis through control of the MDM2 (show MDM2 ELISA Kits)-p53 (show TP53 ELISA Kits) signaling pathway

  9. critical role of caspase 8 (show CASP8 ELISA Kits) in the processing of CSN6.

  10. For the first time our data demonstrate that CSN-mediated deneddylation can be regulated by active Casp3 (show CASP3 ELISA Kits) and that the CSN executes a specific function during the apoptotic process.

COPS6 Antigen Profile

Antigen Summary

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.

Alternative names and synonyms associated with COPS6

  • COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) (COPS6) Elisa Kit
  • COP9 signalosome subunit 6 (Cops6) Elisa Kit
  • COP9 complex homolog subunit 6 (CSN6) Elisa Kit
  • COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) (cops6) Elisa Kit
  • COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana) (Cops6) Elisa Kit
  • COP9 signalosome subunit 6 (COPS6) Elisa Kit
  • Protein CSN-6 (csn-6) Elisa Kit
  • CG6932 Elisa Kit
  • CH6 Elisa Kit
  • CSN6 Elisa Kit
  • Dch6 Elisa Kit
  • Dmel\\CG6932 Elisa Kit
  • MOV34-34KD Elisa Kit
  • Sgn3 Elisa Kit
  • VIP/MOV34 Elisa Kit
  • zgc:112075 Elisa Kit

Protein level used designations for COPS6

COP9 (constitutive photomorphogenic) homolog, subunit 6 , COP9 constitutive photomorphogenic homolog subunit 6 , COP9 signalosome complex subunit 6 , CG6932-PA , CSN6-PA , drosophila COP9 signalosome homolog 6 , COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) , COP9 (constitutive photomorphogenic), subunit 6 , COP9 complex S6 , JAB1-containing signalosome subunit 6 , SGN6 , signalosome subunit 6 , COP9 signalosome subunit 6 , COP9 subunit 6 (MOV34 homolog, 34 kD) , H_NH0506M12.12 , MOV34 homolog, 34 kD , hVIP , vpr-interacting protein

GENE ID SPECIES
479738 Canis lupus familiaris
304343 Rattus norvegicus
42661 Drosophila melanogaster
463587 Pan troglodytes
550465 Danio rerio
26893 Mus musculus
512756 Bos taurus
100125954 Sus scrofa
100171609 Pongo abelii
10980 Homo sapiens
178289 Caenorhabditis elegans
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