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Browse our COPS8 (COPS8) ELISA Kits

Full name:
COP9 Constitutive Photomorphogenic Homolog Subunit 8 (Arabidopsis) ELISA Kits (COPS8)
On www.antibodies-online.com are 0 COP9 Constitutive Photomorphogenic Homolog Subunit 8 (Arabidopsis) (COPS8) ELISA Kits from different suppliers available. Additionally we are shipping COPS8 Antibodies (63) and COPS8 Proteins (12) and many more products for this protein. A total of 83 COPS8 products are currently listed.
Synonyms:
9430009J09Rik, AA408242, CG13383, CG33297, CG42522, CH8, CONSTITUTIVE PHOTOMORPHOGENIC 9, COP9, COP9 SIGNALOSOME SUBUNIT 8, cops8, CSN8, Dch8, DDBDRAFT_0167123, DDBDRAFT_0233107, DDB_0167123, DDB_0233107, DL3095C, Dmel\\CG42522, Dmel_CG13383, EMB143, EMBRYO DEFECTIVE 143, FCAALL.131, FUS7, FUSCA 7, FUSCA PROTEIN FUS7, l(2)SH2 1829, l(2)SH1829, MGC76051, MGC80215, MGC86182, SGN8, zgc:56319, zgc:86840
list all ELISA KIts Gene Name GeneID UniProt
Mouse COPS8 COPS8 108679 Q8VBV7
Human COPS8 COPS8 10920 Q99627
Rat COPS8 COPS8 363283 Q6P4Z9

Show all synonyms

More ELISA Kits for COPS8 Interaction Partners

Fruit Fly (Drosophila melanogaster) COP9 Constitutive Photomorphogenic Homolog Subunit 8 (Arabidopsis) (COPS8) interaction partners

  1. Mutants in protein phosphatase type 2A (PP2A) also display reduced genome-wide H3 dephosphorylation, and sites of H3 phosphorylation that do not contain heat shock genes remain transcriptionally active during heat shock in PP2A mutants.

  2. CSN8 is present exclusively as part of the CSN holo-complex, and lack of CSN8 in the mutants leads to CSN instability. Consistent with this, Cullin (show CUL5 ELISA Kits) deneddylation is impaired in the csn8(null) mutants.

Mouse (Murine) COP9 Constitutive Photomorphogenic Homolog Subunit 8 (Arabidopsis) (COPS8) interaction partners

  1. CSN8/CSN promotes the ubiquitination and degradation of misfolded proteins and protects against cardiac proteotoxicity, and cullin-RING ligases participate in degradation of cytosolic misfolded proteins.

  2. Csn8 exerts profound impacts on hepatic ubiquitin-proteasome system function and is critical to the stability of the pro-apoptotic protein Bim (show BCL2L11 ELISA Kits).

  3. CSN8/COP9 signalosome regulates both proteasome-mediated proteolysis and the autophagic-lysosomal pathway, critical to the removal of oxidized proteins in the heart.

  4. Data indicate that a decreased level of Csn8 accelerated cell growth and shortened G1 duration. (show COPS5 ELISA Kits)

  5. Likely through regulating the expression of Rab7 (show RAB7A ELISA Kits), Csn8/CSN plays a critical role in autophagosome maturation in myocardium.

  6. The Csn8 is essential to the ability of mature hepatocytes to proliferate effectively in response to hepatic injury.

  7. Csn8/CSN plays an essential role in cullin deneddylation, UPS-mediated degradation of a subset of proteins, and the survival of cardiomyocytes

Arabidopsis thaliana COP9 Constitutive Photomorphogenic Homolog Subunit 8 (Arabidopsis) (COPS8) interaction partners

  1. while constitutively photomorphogenic9 (COP9) signalosome (CSN) mutants can complete embryogenesis and are able to germinate, they progressively lose meristem activity upon germination until they become unable to sustain growth

  2. This review provides an overview of the highly complex regulation of CULLIN-RING E3 ubiquitin ligase activity by COP9 signalosome (CSN), and the many roles of the CSN in plant development and defense.

  3. SMAP1 (show SMAP1 ELISA Kits) interacts with the COP9 signalosome.

  4. study concludes that the COP9 signalosome maintains a precise regulation of eIF3e (show EIF3E ELISA Kits) levels, which is necessary for normal development in Arabidopsis

  5. COP9 has a role in ethylene signaling.

  6. COP9 signalosome- and 26S proteasome (show Psmd4 ELISA Kits)-dependent regulation of SCFTIR1 accumulation in Arabidopsis

Human COP9 Constitutive Photomorphogenic Homolog Subunit 8 (Arabidopsis) (COPS8) interaction partners

  1. Data indicate that silencing of Csn8 caused an increased growth rate, whereas silencing of Csn5 (show COPS5 ELISA Kits) impaired proliferation in HeLa cells.

  2. miR (show MLXIP ELISA Kits)-146a expression is up-regulated in a majority of gastric cancers where it targets CARD10 (show CARD10 ELISA Kits) and COPS8, inhibiting GPCR (show NMUR1 ELISA Kits)-mediated activation of NF-kappaB (show NFKB1 ELISA Kits).

  3. analysis of the COP9 signalosome and its common architecture with the 26S proteasome (show Psmd4 ELISA Kits) lid and eIF3 (show EIF3A ELISA Kits)

  4. DDB2 (show DDB2 ELISA Kits) and CSA (show ERCC8 ELISA Kits) are each integrated into nearly identical complexes via interaction with DDB1 (show DDB1 ELISA Kits). Both complexes contain cullin 4A (show CUL4A ELISA Kits) and Roc1 (show RIT1 ELISA Kits) and display ubiquitin ligase activity. They also contain the COP9 signalosome (CSN)

  5. The COP9 signalosome (CSN) controls NF-kappaB (show NFKB1 ELISA Kits) by deubiquitinylation of IkappaBalpha (show NFKBIA ELISA Kits).

  6. COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination

COPS8 Antigen Profile

Antigen Summary

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternative names and synonyms associated with COPS8

  • COP9 complex homolog subunit 8 (CSN8) Elisa Kit
  • COP9 constitutive photomorphogenic homolog subunit 8 (csn8) Elisa Kit
  • COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (COPS8) Elisa Kit
  • MGC80215 protein (MGC80215) Elisa Kit
  • COP9 signalosome complex subunit 8 (CSN8) Elisa Kit
  • COP9 signalosome complex subunit 8 (csn8) Elisa Kit
  • COP9 (constitutive photomorphogenic) homolog, subunit 8 (cops8) Elisa Kit
  • COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana) (Cops8) Elisa Kit
  • COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (cops8) Elisa Kit
  • COP9 signalosome complex subunit 8 (COP9) Elisa Kit
  • COP9 signalosome subunit 8 (COPS8) Elisa Kit
  • COP9 signalosome subunit 8 (Cops8) Elisa Kit
  • 9430009J09Rik Elisa Kit
  • AA408242 Elisa Kit
  • CG13383 Elisa Kit
  • CG33297 Elisa Kit
  • CG42522 Elisa Kit
  • CH8 Elisa Kit
  • CONSTITUTIVE PHOTOMORPHOGENIC 9 Elisa Kit
  • COP9 Elisa Kit
  • COP9 SIGNALOSOME SUBUNIT 8 Elisa Kit
  • cops8 Elisa Kit
  • CSN8 Elisa Kit
  • Dch8 Elisa Kit
  • DDBDRAFT_0167123 Elisa Kit
  • DDBDRAFT_0233107 Elisa Kit
  • DDB_0167123 Elisa Kit
  • DDB_0233107 Elisa Kit
  • DL3095C Elisa Kit
  • Dmel\\CG42522 Elisa Kit
  • Dmel_CG13383 Elisa Kit
  • EMB143 Elisa Kit
  • EMBRYO DEFECTIVE 143 Elisa Kit
  • FCAALL.131 Elisa Kit
  • FUS7 Elisa Kit
  • FUSCA 7 Elisa Kit
  • FUSCA PROTEIN FUS7 Elisa Kit
  • l(2)SH2 1829 Elisa Kit
  • l(2)SH1829 Elisa Kit
  • MGC76051 Elisa Kit
  • MGC80215 Elisa Kit
  • MGC86182 Elisa Kit
  • SGN8 Elisa Kit
  • zgc:56319 Elisa Kit
  • zgc:86840 Elisa Kit

Protein level used designations for COPS8

CG42522-PB , CSN8-PB , Cop9 signalosome subunit 8 , drosophila COP9 signalosome homolog 8 , lethal (2) SH1829 , COP9 signalosome complex subunit 8 , signalosome subunit 8 , COP9 signalosome subunit 8 , MGC80215 protein , COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) , COP9 (constitutive photomorphogenic) homolog, subunit 8 , COP9 homolog , JAB1-containing signalosome subunit 8 , COP9 constitutive photomorphogenic homolog subunit 8 , hCOP9 , SGN8

GENE ID SPECIES
49077 Drosophila melanogaster
394711 Xenopus (Silurana) tropicalis
424020 Gallus gallus
443917 Xenopus laevis
8620221 Dictyostelium discoideum AX4
100286467 Salmo salar
460043 Pan troglodytes
477417 Canis lupus familiaris
540493 Bos taurus
447626 Xenopus laevis
108679 Mus musculus
100171561 Pongo abelii
393198 Danio rerio
827049 Arabidopsis thaliana
10920 Homo sapiens
363283 Rattus norvegicus
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