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anti-Human Cyclin B1 Antibodies:
anti-Mouse (Murine) Cyclin B1 Antibodies:
anti-Rat (Rattus) Cyclin B1 Antibodies:
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Hamster Monoclonal Cyclin B1 Primary Antibody for BI, FM - ABIN967426
Cao, Faha, Dembski, Tsai, Harlow, Dyson: Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. in Nature 1992
Show all 13 Pubmed References
Human Polyclonal Cyclin B1 Primary Antibody for WB - ABIN3043482
Ren, Huang, Xu, Yang, Yang, Hu: Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells. in Anti-cancer drugs 2015
Show all 12 Pubmed References
Human Polyclonal Cyclin B1 Primary Antibody for FACS, IF (cc) - ABIN670296
Ghate, Chaudhuri, Sarkar, Sajem, Panja, Rout, Mandal: An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7. in PLoS ONE 2013
Show all 7 Pubmed References
Human Monoclonal Cyclin B1 Primary Antibody for BI, FACS - ABIN967428
Dunphy, Brizuela, Beach, Newport: The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis. in Cell 1988
Show all 9 Pubmed References
Human Polyclonal Cyclin B1 Primary Antibody for DB, WB - ABIN1881155
Kreis, Sanhaji, Krämer, Sommer, Rödel, Strebhardt, Yuan: Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells. in Oncogene 2010
Show all 3 Pubmed References
Human Monoclonal Cyclin B1 Primary Antibody for ICC, FACS - ABIN969006
Chou, Yen, Lee, Chen: Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domain. in The Journal of biological chemistry 2010
Show all 2 Pubmed References
Human Monoclonal Cyclin B1 Primary Antibody for IHC, ELISA - ABIN969005
Okayama, Kumamoto, Saitou, Hayase, Kofunato, Sato, Miyamoto, Nakamura, Ohki, Sekikawa, Takenoshita: CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer. in Oncology reports 2009
Show all 2 Pubmed References
Mouse (Murine) Polyclonal Cyclin B1 Primary Antibody for IHC, WB - ABIN3022807
Cheng, Yang, Fang, Ma, Gong, Wang, Li, Xu: Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation. in Nature communications 2015
Human Polyclonal Cyclin B1 Primary Antibody for ELISA, WB - ABIN129589
Geng, Zhang, Zheng, Legerski: Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B. in Molecular and cellular biology 2007
Human Polyclonal Cyclin B1 Primary Antibody for IF (p), IHC (p) - ABIN684448
Hawash, Kahraman, Eren, Cetin Atalay, Baytas: Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics. in European journal of medicinal chemistry 2017
intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (show CDK1 Antibodies), wee1 (show WEE1 Antibodies), p21 (show CDKN1A Antibodies), PCNA (show PCNA Antibodies) and cdk2 (show CDK2 Antibodies), but only weakly influences cyclin B1, cyclin B2 (show CCNB2 Antibodies) and cyclin E1 (show CCNE1 Antibodies) expression.
the sequence in the coding region of cyclin B1 mRNA plays an important role as a cis (show CISH Antibodies)-acting element in both subcellular localization and translational timing of mRNA
Reporter mRNAs with the whole cyclin B1 sequence precisely mimic the localization & translation of endogenous cyclin B1 mRNA. mRNAs containing cyclin B1 3' UTR (show UTS2R Antibodies) but lacking ORFs had abnormal localization & precocious translational activation.
zebrafish cyclin B1 3'UTR (show UTS2R Antibodies) was quantitatively less effective at stimulating polyadenylation and translation compared to the Xenopus cyclin B1 3'UTR (show UTS2R Antibodies) during both zebrafish and Xenopus oocyte maturation
Data show that CDK1 (show CDK1 Antibodies) and cyclin B synergize during oocyte maturation to inhibit Myt1 (show PKMYT1 Antibodies) ensuring meiotic progression.
new role for Erk (show MAPK1 Antibodies) in mitotic regulation, identification of the Ser (show SIGLEC1 Antibodies) 101-directed kinase, and a picture of cyclin B1/Cdc2 regulation by the combinatorial action of distinct kinases
Cyclin B1 displays cytoskeleton-dependent localization in blastomere cortex during Xenopus embryonic cell cycle.
Cyclin B dissociation from CDK1 (show CDK1 Antibodies) precedes cyclins B degradation upon CDK1 (show CDK1 Antibodies) inactivation in mitotic embryo extracts and that proteasome proteolytic activity is dispensable for both activation and inactivation of CDK1 (show CDK1 Antibodies) in such extracts.
XIAP (show XIAP Antibodies) is stable during mitotic arrest, but its function is controlled through phosphorylation by the mitotic kinase CDK1 (show CDK1 Antibodies)-cyclin-B1 at S40.
ZIC5 (show ZIC5 Antibodies) is highly upregulated in non-small cell lung cancer tumor tissues and may act as an oncogene (show RAB1A Antibodies) by influencing CCNB1 and CDK1 (show CDK1 Antibodies) complex expression
Knockdown of DRG2 (show DRG2 Antibodies) elicited down-regulation of the major mitotic promoting factor, the cyclin B1/Cdk1 (show CDK1 Antibodies) complex.
Mitochondrial Ribosomal Protein L10 regulates cyclin B1/Cdk1 (cyclin-dependent kinase 1 (show CDK1 Antibodies)) activity and mitochondrial protein (show COX6B2 Antibodies) synthesis in mammalian cells
Changes in expression and localization of cyclin B1 may constitute a part of the mechanism responsible for resistance of HL-60 cells to etoposide.
Data suggest that long non-coding RNA ZFAS1 may function as oncogene (show RAB1A Antibodies) via destabilization of tumor suppressor protein p53 (p53 (show TP53 Antibodies)) and through cyclin-dependent kinase 1 (CDK1 (show CDK1 Antibodies))/cyclin B1 complex leading to cell cycle progression and inhibition of apoptosis.
exposing renal carcinoma (show TSC2 Antibodies) cells to amygdalin inhibited cell cycle progression and tumor cell growth by impairing cdk1 (show CDK1 Antibodies) and cyclin B expression
Together, these results demonstrate that PGC-1alpha (show PPARGC1A Antibodies) regulates cell cycle progression through modulation of CyclinD1 and CyclinB1 by ATP and ROS (show ROS1 Antibodies).
On analyzing cyclin A (show CCNA2 Antibodies) and B1 (CCNA (show CCNA2 Antibodies) and CCNB1) expression, positive staining in 90% cases of PTC (show F9 Antibodies) were observed. The study revealed a significant difference in expression of cyclins A and B1 between classic and non-classic variants of PTC (show F9 Antibodies).
Sodium butyrate accelerates 3' UTR (show UTS2R Antibodies)-dependent cyclin B1 decay by enhancing the binding of tristetraprolin (show ZFP36 Antibodies) to the 3' untranslated region of cyclin B1.
Inhibition of CDK7 (show CDK7 Antibodies) bypasses spindle assembly checkpoint via premature cyclin B degradation during oocyte meiosis.
timing of Ccnb1 mRNA translation in mouse oocytes is dependent on the presence of transcripts with different 3' untranslated regions
AURKA (show AURKA Antibodies) induced phosphorylation and recruitment of CDC25B (show CDC25B Antibodies) to MTOCs prior to p-Cyclin B1-Ser123, and this sequential regulation is essential for the commitment of the oocytes to resume meiosis.
that MAD2B may play an important role in high glucose-mediated podocyte injury of diabetic nephropathy via modulation of Cdh1, cyclin B1, and Skp2 expression
Parvovirus-induced depletion of cyclin B1 prevents mitotic entry of infected cells.
Cyclin B1/Cdk1 (show CDK1 Antibodies)-mediated phosphorylation of mitochondrial substrates allows cells to sense and respond to increased energy demand for G2/M transition and, subsequently, to upregulate mitochondrial respiration for successful cell-cycle progression.
sticky siRNAs against survivin (show BIRC5 Antibodies) and cyclin B1 efficiently blocks growth of established subcutaneaous B16-F10 (show F10 Antibodies) tumors as well as formation and dissemination of melanoma lung metastases.
Inhibitions of Aurora B (show AURKC Antibodies) and Cyclin-dependent kinase 1 (show CDK1 Antibodies) activity in vertebrate cells also have opposite effects on the timing of abscission.
It was concluded that insensitivity of mouse germinal vesicle oocytes to cyclohexidine was due to the presence of sufficient cyclin B1, and that cyclin B1 level in such oocytes was maintained by an equilibrium between synthesis and degradation.
Data show nuclear accumulation of cyclin B1 with a subsequent premature increase in G2/M kinase activity in Nipa (show ZC3HC1 Antibodies)-/- spermatocytes.
Cyclin B1 plays a significant role in promoting the maturation of large-follicle oocytes.
cyclin B1 distribution in porcine oocytes is affected by demecolcine-assisted enucleation
germinal vesicle is not required for the activation of M phase promoting factor during the first meiosis, but it is required for the second meiosis because of its promotion of CCNB1 accumulation
Results describe the expression of maternal cyclin B1 and Cdc2 (show CDK1 Antibodies) during in vitro maturation of porcine oocytes.
Cyclin-dependent kinase (show CDK1 Antibodies) inhibition did not affect the expression (mRNA and protein levels) and localization of maturation promoting factor(MPF (show MSLN Antibodies)) and MAPK (show MAPK1 Antibodies), and had nearly no effect on kinase activities during maturation.
link between cytoplasmic polyadenylation of cyclin B1 and translation/appearance of cyclin B1 protein before in vitro maturation of oocytes
Polyadenylation of cyclin B1 was also completely prevented when 3'-dA was added at 0 hr, and greatly reduced when added at 6 hr
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
, cyclin B1
, cyclin B4
, G2/mitotic-specific cyclin B1
, cyclin B1, related sequence 1
, cyclin B1, related sequence 13
, cyclin B