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Browse our Cyclin C Proteins (CCNC)

Full name:
Cyclin C Proteins (CCNC)
On www.antibodies-online.com are 13 Cyclin C (CCNC) Proteins from 5 different suppliers available. Additionally we are shipping Cyclin C Antibodies (65) and Cyclin C Kits (2) and many more products for this protein. A total of 86 Cyclin C products are currently listed.
Synonyms:
AI451004, AU020987, CG1C, CG1C_DROME, CG7281, Cln3, Cyc-C, CycC, Cyclin-C, cyclinC, DmcycC, Dmel\\CG7281, dTRAP33, fj11d06, SRB11, wu:fj11d06, zgc:73078
list all proteins Gene Name GeneID UniProt
CCNC 892 P24863
CCNC 51813 Q62447
CCNC 114839  

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Cyclin C Proteins (CCNC) by Origin

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More Proteins for Cyclin C Interaction Partners

Fruit Fly (Drosophila melanogaster) Cyclin C (CCNC) interaction partners

  1. CDK8-CycC may serve as transcriptional cofactors for EcR-dependent transcription.

  2. observed biochemical association between Integrator proteins and cyclin C/Cdk8 (show CDK8 Proteins), and that overexpression of a kinase-dead Cdk8 (show CDK8 Proteins) causes snRNA misprocessing

Human Cyclin C (CCNC) interaction partners

  1. our results suggest that mTORC1 activation in NAFLD and insulin (show INS Proteins) resistance results in down-regulation of the CDK8 (show CDK8 Proteins)-CycC complex and elevation of lipogenic protein expression.

  2. results suggest that CCNC temporarily protects SRC-2 (show NCOA2 Proteins) against degradation and this event is involved in the transcriptional regulation of SRC-2 (show NCOA2 Proteins) cell cycle target genes.

  3. Cancer-mediated CDK8 (show CDK8 Proteins) point mutations (D173A and D189N) change the binding pattern of cdk8 (show CDK8 Proteins) to its partner, CycC.

  4. cyclin-C-CDK (show CDK4 Proteins) complexes phosphorylate the Notch1 (show NOTCH1 Proteins) intracellular domain (ICN1) and promote ICN1 degradation

  5. analysis of the structure-kinetic relationship of the cyclin-dependent kinase 8 (CDK8 (show CDK8 Proteins))/cyclin C (CycC) complex

  6. Silencing beta-catenin (show CTNNB1 Proteins) gene may induce changes of cell cycle and in cyclin B1 (show CCNB1 Proteins) and cyclin C protein (show HNRNPC Proteins) expression.

  7. 2.2-A crystal structure of CDK8 (show CDK8 Proteins)/CycC in complex with sorafenib; CDK8 (show CDK8 Proteins) structure reveals a unique CycC recognition helix that explains the specificity of the CDK8 (show CDK8 Proteins)/CycC pair and discrimination among the highly promiscuous binding in the CDK (show CDK4 Proteins)/cyclin (show PCNA Proteins) family

  8. Studies establish cyclin C as a critical regulator of the G(0)/G(1) transition of human HSPCs and suggest that modulating cyclin C levels may be useful for HSC (show FUT1 Proteins) expansion and more efficient engraftment.

  9. The present observations suggest different cellular functions of cyclin C in neurons and astrocytes in alzheimer's disease.

  10. A cellular pool of cyclin C combines with cdk3 (show CDK3 Proteins) to stimulate pRb (show RB1 Proteins) phosphorylation at S807/811 during the G0/G1 transition, and this phosphorylation is required for cells to exit G0 efficiently.

Mouse (Murine) Cyclin C (CCNC) interaction partners

  1. our results suggest that mTORC1 activation in NAFLD and insulin (show INS Proteins) resistance results in down-regulation of the CDK8 (show CDK8 Proteins)-CycC complex and elevation of lipogenic protein expression.

  2. cyclin C connects stress-induced mitochondrial hyperfission and programmed cell death in mammalian cells.

  3. cyclin-C-CDK (show CDK4 Proteins) complexes phosphorylate the Notch1 (show NOTCH1 Proteins) intracellular domain (ICN1) and promote ICN1 degradation

  4. Data show that the isolated 3.6-KB promoter fragment alone is not sufficient for the complete physiological modulation of cyclin C RNA.

  5. Results identify LSF (show TFCP2 Proteins) as only the second known target (in addition to pRb (show PGR Proteins)) of cyclin C/CDK2 (show CDK2 Proteins) activity during progression from quiescence to early G(1).

Cyclin C (CCNC) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Cyclin C (CCNC)

  • Cyclin C (CycC)
  • cyclin C (ccnc)
  • cyclin C (CCNC)
  • cyclin C (Ccnc)
  • g1/s-specific cyclin c (AaeL_AAEL013397)
  • AI451004 protein
  • AU020987 protein
  • CG1C protein
  • CG1C_DROME protein
  • CG7281 protein
  • Cln3 protein
  • Cyc-C protein
  • CycC protein
  • Cyclin-C protein
  • cyclinC protein
  • DmcycC protein
  • Dmel\\CG7281 protein
  • dTRAP33 protein
  • fj11d06 protein
  • SRB11 protein
  • wu:fj11d06 protein
  • zgc:73078 protein

Protein level used designations for Cyclin C Proteins (CCNC)

cyclin C , CG7281-PA , CycC-PA , cyclin-C , SRB11 homolog , hSRB11 , dJ199J3.4 (cyclin C)

GENE ID SPECIES
41801 Drosophila melanogaster
335429 Danio rerio
394762 Xenopus (Silurana) tropicalis
100153639 Sus scrofa
475007 Canis lupus familiaris
892 Homo sapiens
51813 Mus musculus
114839 Rattus norvegicus
509717 Bos taurus
421791 Gallus gallus
734677 Xenopus laevis
5577815 Aedes aegypti
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