Browse our anti-E2F2 (E2F2) Antibodies

Full name:
anti-E2F Transcription Factor 2 Antibodies (E2F2)
On are 74 E2F Transcription Factor 2 (E2F2) Antibodies from 22 different suppliers available. Additionally we are shipping E2F2 Proteins (6) and E2F2 Kits (4) and many more products for this protein. A total of 94 E2F2 products are currently listed.
9230110J10, CG1071, dE2F-2, de2f2, Dmel\\CG1071, E2F, E2F-2, e2f2, E130207A07
list all antibodies Gene Name GeneID UniProt
E2F2 1870 Q14209
E2F2 242705 P56931
E2F2 684111  

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anti-Human E2F2 Antibodies:

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Top referenced anti-E2F2 Antibodies

  1. Human Monoclonal E2F2 Primary Antibody for IP, WB - ABIN967548 : Lukas, Petersen, Holm, Bartek, Helin: Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression. in Molecular and cellular biology 1996 (PubMed)
    Show all 5 references for 967548

  2. Human Polyclonal E2F2 Primary Antibody for EIA, WB - ABIN492946 : Iglesias, Murga, Laresgoiti, Skoudy, Bernales, Fullaondo, Moreno, Lloreta, Field, Real, Zubiaga: Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice. in The Journal of clinical investigation 2004 (PubMed)
    Show all 4 references for 492946

  3. Human Polyclonal E2F2 Primary Antibody for WB - ABIN654438 : Revenko, Kalashnikova, Gemo, Zou, Chen: Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark. in Molecular and cellular biology 2010 (PubMed)
    Show all 2 references for 654438

  4. Cow (Bovine) Polyclonal E2F2 Primary Antibody for WB - ABIN2777378 : Iwata, Maruyama, Akagi, Hashikawa, Kanazawa, Tsuji, Nukina: Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies. in Human molecular genetics 2003 (PubMed)
    Show all 2 references for 2777378

  5. Human Polyclonal E2F2 Primary Antibody for WB - ABIN871757 : Rubin, Gall, Zheng, Pavletich: Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. in Cell 2005 (PubMed)

  6. Human Polyclonal E2F2 Primary Antibody for ELISA, WB - ABIN1533884 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)

  7. Cow (Bovine) Polyclonal E2F2 Primary Antibody for IHC, WB - ABIN2780568 : Raj, Liu, Samadashwily, Li, Grossman: Survivin repression by p53, Rb and E2F2 in normal human melanocytes. in Carcinogenesis 2008 (PubMed)

More Antibodies against E2F2 Interaction Partners

Fruit Fly (Drosophila melanogaster) E2F Transcription Factor 2 (E2F2) interaction partners

  1. E2F directly regulates the expression of late myogenic genes, with E2f1 (show E2F1 Antibodies) providing the major contribution compared with E2f2.

  2. The dE2F2 protein repress the expression of buffy, the anti-apoptotic member of the Bcl-2 (show BCL2 Antibodies) family and activate the expression of an RNA-binding protein that destabilizes diap1 (show DIAPH1 Antibodies) in Drosophila.

  3. Heterozygous mutation of mip120 (show LIN54 Antibodies) or E2f2 suppressed the binucleate cell phenotype in the peripodial epithelium of Myb (show MYB Antibodies)-null wing discs.

  4. dE2F2, as well as the net E2F activity, which can be depleted by mutating the common cofactor, dDp (show TIMM8A Antibodies), is inhibitory for p53 (show TUBB Antibodies)-independent apoptosis.

  5. RBF1 and RBF2 interact with different subsets of E2F proteins; this enables the RBF (show ATP5I Antibodies) proteins to regulate E2F-dependent transcription in distinct ways

  6. cells containing dE2F2 require dE2F1 (show E2F1 Antibodies) to either prevent, or reverse, dE2F (show E2F1 Antibodies)-mediated repression

  7. Data show that removal of p55 deregulated the expression of E2F targets that are normally repressed by dE2F2/RBF-1 and -2 complexes in a cell cycle-independent manner but had no effect on the expression of targets normally coupled with cell proliferation.

  8. examination of linking together the Myb (show MYB Antibodies) and E2F2 complexes in higher-order assembly to specific chromosomal sites for the regulation of transcription

  9. RBF2 has a unique function in repressing E2F-regulated differentiation markers and dE2F2 and RBF2 are required to regulate different sets of target genes in different tissues

  10. Thease results demonstrate epigenetic regulation of gene expression by Myb (show MYB Antibodies), and E2F2-RBF (show ATP5I Antibodies) in vivo, and also provide an explanation for the ability of Mip130-null mutants to rescue the lethality of Myb (show MYB Antibodies)-null mutants in vivo.

Human E2F Transcription Factor 2 (E2F2) interaction partners

  1. Let-7b inhibits the malignant behavior of glioma cells and glioma stem-like cells via downregulation of E2F2.

  2. In NSCLC patients, E2F2 expression was found to be significantly correlated with sex and tumor size. E2F1 (show E2F1 Antibodies) and E2F2 overexpression showed a significant association with poor prognosis.

  3. Data indicate that microRNA miR (show MLXIP Antibodies)-214 has tumor-suppressive activity in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) through inhibition of E2F2 transcription factor (E2F2), cyclin (show PCNA Antibodies)-dependent kinases CDK3 (show CDK3 Antibodies) and CDK6 (show CDK6 Antibodies).

  4. we validated for the first time that E2F2 acts as a tumor activator in non-small cell lung carcinoma.

  5. E2F2 loss results in increased lung metastasis in breast cancer, potentially functioning through a PTPRD (show PTPRD Antibodies) dependent mechanism.

  6. Elevated E2F2 expression in glioblastoma cells weakens the effect of elevated levels of miR (show MLXIP Antibodies)-218.

  7. cell cycle-dependent transcription of the TRAIP (show TRAIP Antibodies) gene by E2F1 (show E2F1 Antibodies), E2F2, and E2F4 (show E2F4 Antibodies) and rapid protein degradation leads to cell cycle-dependent expression with a maximum in G2/M

  8. miR218 and miR520a are crucial in the development of hepatocellular carcinoma via the inhibition of cell proliferation and cycle progression by downregulating E2F2.

  9. miR (show MLXIP Antibodies)-31 regulated the proliferation of colon cancer cells by targeting E2F2.

  10. Results show evidence that let-7a expression in osteosarcoma (OS) cells is significantly reduced and inversely correlated with E2F2 expression levels and that let-7a plays an important role in OS cell proliferation and tumorigenesis by targeting E2F2.

Mouse (Murine) E2F Transcription Factor 2 (E2F2) interaction partners

  1. Findings implicate E2F-2 in regulating the expression of mitotic kinases that are adapted to perform specialized functions in nuclear condensation and enucleation of maturing erythroblasts.

  2. Spinal cord injury-induced activation of E2F1 (show E2F1 Antibodies)-2 mediates cell cycle activation, contributing to gliopathy and neuronal/tissue loss associated with motor impairments and post-traumatic hyperesthesia.

  3. E2F2 loss results in increased lung metastasis in breast cancer, potentially functioning through a PTPRD (show PTPRD Antibodies) dependent mechanism.

  4. A role for E2F1 (show E2F1 Antibodies) and E2F2 as suppressors of replicative stress in differentiating cells, and the existence of a robust E2F (show E2F1 Antibodies)-p53 (show TP53 Antibodies) regulatory axis in tissue homeostasis enabling and tumorigenesis preventing is shown.

  5. E2F2 accumulates at sites of oxidative and UV-induced DNA damage, and interact with gammaH2AX (show H2AFX Antibodies) DNA repair factor.

  6. E2F2 activity sustains the hepatic homeostasis of major membrane glycerolipid components while it is dispensable for storage glycerolipid balance.

  7. Rb-deficient cells hijack and redeploy Myc (show MYC Antibodies) and E2f3 from an S-G2 (show STRN3 Antibodies) program essential for normal cell cycles to a G1-S program that re-engages ectopic cell cycles, exposing an unanticipated addiction of Rb-null cells on Myc (show MYC Antibodies).

  8. showed that the D326V missense pRb (show PGR Antibodies) bound to E2F1 (show E2F1 Antibodies) but failed to interact with E2F2/3

  9. E2F3 promotes while E2F2 suppresses ischemic cardiac repair through corresponding changes in endothelial cell proliferation.

  10. E2F2 impairs, and endothelial E2F3 promotes, the angiogenic response to peripheral ischemic injury through corresponding changes in EC cell-cycle progression.

E2F2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1.

Alternative names and synonyms associated with E2F2

  • E2F transcription factor 2 (E2f2) antibody
  • E2F transcription factor 2 (E2F2) antibody
  • Macrophage stimulating 1 (hepatocyte growth factor-like) (Mst1) antibody
  • 9230110J10 antibody
  • CG1071 antibody
  • dE2F-2 antibody
  • de2f2 antibody
  • Dmel\\CG1071 antibody
  • E2F antibody
  • E2F-2 antibody
  • e2f2 antibody
  • E130207A07 antibody

Protein level used designations for E2F2

CG1071-PA , E2f2-PA , transcription factor E2F2 , E2F-2 , D8h3f15s2 , E2F transcription factor 2 , hepatocyte growth factor-like protein

35381 Drosophila melanogaster
1870 Homo sapiens
617024 Bos taurus
242705 Mus musculus
425366 Gallus gallus
100684439 Canis lupus familiaris
684111 Rattus norvegicus
24566 Rattus norvegicus
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