Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
The data demonstrated that elevated miR (show MLXIP ELISA Kits)-150 targets FOXO4 expression and therefore regulates multiple genes expression, resulting in cervical cancer cell growth and survival.
Porphyromonas gingivalis-induced reactive oxygen species activate FOXO (show FOXO3 ELISA Kits) transcription factors through JNK (show MAPK8 ELISA Kits) signalling, and that FOXO1 (show FOXO1 ELISA Kits) controls oxidative stress responses, inflammatory cytokine production and cell survival.
Cox (show COX8A ELISA Kits) regression analysis indicated FoxO4 to be an independent prognostic factor in non-small cell lung cancers and suggested that FoxO4 might inhibit the process of EMT (show ITK ELISA Kits) in non-small cell lung cancers, and might therefore be a target for therapy.
FOXOs support the metabolic requirements of normal and tumor cells by promoting IDH1 (show IDH1 ELISA Kits) expression.
data strongly suggest that increased PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits)-mediated metastatic invasiveness in CaP is associated with FOXO4 loss, and that mechanisms to induce FOXO4 re-expression might suppress CaP metastatic aggressiveness.
study demonstrated that miR (show MLXIP ELISA Kits)-1274a prompted gastric cancer cells growth and migration through dampening FOXO4 expression thus provided a potential target for human gastric cancer therapy
Data indicate that glycogen synthase kinase 3 beta (GSK3beta) and transcription factors FOXO1/3/4 promote hepatoma cell proliferation through type I insulin-like growth factor receptor (IGF-IR).
Case Report: CIC (show CIC ELISA Kits)-FOXO4 fusion sarcoma is a new type of Ewing-like sarcoma that has a specific genetic signature.
Our data suggest that loss of FOXO4 expression contributes to gastric cancer growth and metastasis, and it may serve as a potential therapeutic target for gastric cancer.
results demonstrate that HKa (show ATP4A ELISA Kits) accelerates the onset of EPC (show TCF21 ELISA Kits) senescence by stimulating JNK (show MAPK8 ELISA Kits)/FOXO4/MnSOD (show SOD2 ELISA Kits) pathway, its effect is mediated by the HC
The effect of Sirt1 (show SIRT1 ELISA Kits) stimulators on osteoclastogenesis was abrogated in cells lacking FoxO1 (show FOXO1 ELISA Kits), FoxO3 (show FOXO3 ELISA Kits), and FoxO4.
FoxO4 is collectively required to maintain MODYrelated gene networks, which in turn are required to enable a gene expression program that permits proper substrate selection (glucose versus fatty acids) for mitochondrial oxidative phosphorylation.
FoxO4 transcription factor is present during both oocyte and embryo in vivo maturation and FoxOs may regulate in vitro embryo development under stress conditions.
FoxO4 activates Arg1 (show ARG1 ELISA Kits) transcription in endothelial cells in response to MI, leading to downregulation of nitric oxide and upregulation of neutrophil infiltration to the infarct area.
Foxo1, Foxo3, and Foxo4 transcriptional network regulates autophagy and the ubiquitin-proteasome system during muscle atrophy.
Liver-specific ablation of FoxO1 (show FOXO1 ELISA Kits),FoxO3 (show FOXO3 ELISA Kits) and FoxO4 prevents the induction of glucose-6-phosphatase (show G6PC ELISA Kits) and the repression of glucokinase (show GCK ELISA Kits) during fasting, thus increasing lipogenesis.
FOXO1 (show FOXO1 ELISA Kits), FOXO3a (show FOXO3 ELISA Kits) and FOXO4, are indispensable for SIRT1 (show SIRT1 ELISA Kits)-dependent cell survival against oxidative stress.
FoxO1 (show FOXO1 ELISA Kits)/3/4 transcription factors play important roles in hepatic glucose homeostasis.
Mice lacking Foxo1 (show FOXO1 ELISA Kits), -3, and -4 in bipotential progenitors of osteoblast and adipocytes exhibit increased osteoblast number and high bone mass.
Foxk1 promotes muscle progenitor cell proliferation by repressing Foxo4 transcriptional activity and inhibits myogenic differentiation by repressing Mef2 activity.
This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.
similar to Putative fork head domain transcription factor AFX1 (Forkhead box protein O4)
, forkhead box O4
, forkhead box protein O4-like
, fork head domain transcription factor AFX1
, forkhead box protein O4
, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7
, forkhead protein
, myeloid/lymphoid or mixed lineage-leukemia translocation to 7 homolog
, forkhead box O1A