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Browse our MDM2 (MDM2) ELISA Kits

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Mdm2 P53 Binding Protein Homolog (Mouse) ELISA Kits (MDM2)
On are 1 Mdm2 P53 Binding Protein Homolog (Mouse) (MDM2) ELISA Kits from 1 different suppliers available. A total of 1 MDM2 products are currently listed.
1700007J15Rik, AA415488, ACTFS, hdm2, HDMX, Mdm-2
list all ELISA KIts Gene Name GeneID UniProt
MDM2 4193 Q00987
Mouse MDM2 MDM2 17246 P23804

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Human Mdm2 P53 Binding Protein Homolog (Mouse) (MDM2) interaction partners

  1. the MDM2 SNP309 G/G homozygous genotype might be a risk factor for gastric cancer in Thailand

  2. The proposed non-linear feedback control and perturbations compensation method for the p53 (show TP53 ELISA Kits)-mdm2 system can result in more efficient chemotherapy schemes where the infusion of medication will be better administered.

  3. we demonstrated that rLZ-8 promoted the interaction between MDM2 and Slug (show SNAI2 ELISA Kits), resulting in Slug (show SNAI2 ELISA Kits) degradation

  4. Both cases positive for MDM2 amplification showed MDM2 expression by immunohistochemistry. At last follow-up, both patients had died of disease

  5. This review will focus on the aberrant splicing of tumor suppressor/oncogenes that belong to the DMP1 (show DMP1 ELISA Kits)-ARF-MDM2-p53 (show TP53 ELISA Kits) pathway

  6. The cholesterol metabolite 27-hydroxycholesterol may contribute to ER-positive breast cancer progression by disrupting constitutive p53 (show TP53 ELISA Kits) signaling in an MDM2-dependent manner.

  7. Data show that proto-oncogene (show RAB1A ELISA Kits) protein Mdm2 inactivation successfully protects tumor suppressor protein (p53 (show TP53 ELISA Kits))-proficient cells against the cytotoxic effects of Wee1 (show WEE1 ELISA Kits) protein inhibition.

  8. underscore the importance of TP53 (show TP53 ELISA Kits) R72P and MDM2 SNP309 SNPs in myelodysplastic syndromes

  9. MDM2 may be less effective than inducing p53 (show TP53 ELISA Kits)-independent cell death

  10. RNF12 (show RLIM ELISA Kits) is a novel positive regulator of p53 (show TP53 ELISA Kits) pathway and an external E3 ubiquitin ligase for MDM2 destruction.

Mouse (Murine) Mdm2 P53 Binding Protein Homolog (Mouse) (MDM2) interaction partners

  1. These studies demonstrate that Mdm2 holds promise as a therapeutic target in combination with conventional therapy and may lead to new clinical therapies for Triple-negative breast cancers .

  2. there is a fine tuned balance in the interaction of ribosomal proteins with the MDM2/p53 (show TP53 ELISA Kits) axis which is important in normal hematopoiesis.

  3. Study showed that demonstrate that Mdm2 intertwines the mammalian target of RAPA (show TRERF1 ELISA Kits), mTOR (show FRAP1 ELISA Kits), and the receptor kinase GRK2 (show ADRBK1 ELISA Kits) in regulating the desensitization/inactivation of the GPR17 (show GPR17 ELISA Kits) receptor

  4. MDM2 mediates p73 (show ARHGAP24 ELISA Kits) ubiquitination

  5. MDM2 supports the PRC2 mediated repression of lineage-specific genes in stem cells, independent of p53 (show TP53 ELISA Kits).

  6. physiological activation of the 5S RNP (show RNPC3 ELISA Kits)-Mdm2-p53 (show TP53 ELISA Kits) pathway may contribute to functional decline of the hematopoietic system in a cell-autonomous manner over time.

  7. Ribosomal proteins L11 (show RPL11 ELISA Kits) and L5 activate TAp73 (show TP73 ELISA Kits) by overcoming MDM2 inhibition.

  8. The Mdm2(SNP309-)(G) allele significantly impacts CRC (show SCRIB ELISA Kits) through mechanisms outside the p53 (show TP53 ELISA Kits) pathway.

  9. MDM2 maintains homeostasis and long survival in podocytes preventing apoptosis.

  10. our results show MDM4 (show MDM4 ELISA Kits)-MDM2/p53 (show TP53 ELISA Kits)-IGF1R (show IGF1R ELISA Kits) as an original regulatory mechanism for CNS regeneration

MDM2 Antigen Profile

Antigen Summary

This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues.

Alternative names and synonyms associated with MDM2

  • MDM2 oncogene, E3 ubiquitin protein ligase (MDM2) Elisa Kit
  • transformed mouse 3T3 cell double minute 2 (Mdm2) Elisa Kit
  • 1700007J15Rik Elisa Kit
  • AA415488 Elisa Kit
  • ACTFS Elisa Kit
  • hdm2 Elisa Kit
  • HDMX Elisa Kit
  • Mdm-2 Elisa Kit

Protein level used designations for MDM2

E3 ubiquitin-protein ligase Mdm2 , Mdm2, p53 E3 ubiquitin protein ligase homolog , Mdm2, transformed 3T3 cell double minute 2, p53 binding protein , double minute 2, human homolog of; p53-binding protein , oncoprotein Mdm2 , double minute 2 protein , p53-binding protein Mdm2

4193 Homo sapiens
17246 Mus musculus
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