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Browse our MYBL2 (MYBL2) ELISA Kits

Full name:
V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 ELISA Kits (MYBL2)
On www.antibodies-online.com are 8 V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) ELISA Kits from 4 different suppliers available. Additionally we are shipping MYBL2 Antibodies (103) and MYBL2 Proteins (6) and many more products for this protein. A total of 128 MYBL2 products are currently listed.
Synonyms:
B-MYB, BMYB, myb1, MYBL2
list all ELISA KIts Gene Name GeneID UniProt
MYBL2 296344  
MYBL2 17865 P48972
MYBL2 4605 P10244

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MYBL2 (MYBL2) ELISA Kits by Reactivity

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More ELISA Kits for MYBL2 Interaction Partners

Zebrafish V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) interaction partners

  1. loss-of-function mutation (crb) in bmyb causes defects in mitotic progression and spindle formation and genome instability in embryos, and cancer susceptibility in adult crb heterozygotes

Mouse (Murine) V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) interaction partners

  1. B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development.

  2. MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia.

  3. Results coupled with functional studies demonstrate that B-MYB not only controls and accelerates cell cycle progression in ESCs (show NR2E3 ELISA Kits) it contributes to fate decisions and maintenance of pluripotent stem cell identity.

  4. Our data suggest that B-Myb is required as a pioneer factor to enable FoxM1 (show FOXM1 ELISA Kits) binding to G2/M gene promoters and explains how these transcription factors may collaborate to induce mitosis.

  5. Mybl2 upregulation induces fast growth and progression of premalignant and malignant liver, through cell cycle deregulation and activation of genes and pathways related to tumor progression.

  6. The transcription factor B-Myb is maintained in an inhibited state in target cells through its interaction with the nuclear corepressors N-CoR and SMRT.

  7. Results describe the characterization of a corepressor site (downstream repression site (DRS (show SRPX ELISA Kits))) required for transcriptional regulation of the B-myb (MybL2 gene) promoter.

  8. B-Myb repressor function is regulated by cyclin A phosph (show CCNA2 ELISA Kits)orylation and sequences within the C-terminal domain.

  9. B-Myb has a role in regulation of c-Myc (show MYC ELISA Kits) expression by cytosolic phospholipase A2 (show PLA2G4A ELISA Kits)

  10. B-Myb represses SMC (show DYM ELISA Kits) elastin (show ELN ELISA Kits) gene expression and cyclin A (show CCNA2 ELISA Kits) plays a role in the developmental regulation of elastin (show ELN ELISA Kits) gene expression in the aorta

Human V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) interaction partners

  1. Data indicate that gene expression alterations in endometrial carcinoma samples with high ATAD2 (show ATAD2 ELISA Kits) expression showed upregulation of several cancer-related genes including B-MYB gene.

  2. We found that B-Myb upregulated expression of the key epithelial-to-mesenchymal transition regulator snail (show SNAI1 ELISA Kits) and that it mediated epithelial-to-mesenchymal transition activation and cell invasion by B-Myb.

  3. conclude that downregulation of MYBL2 activity below levels predicted by classical haploinsufficiency underlies the clonal expansion of hematopoietic progenitors in a large fraction of human myeloid malignancies

  4. Suggest B-myb had critical roles in both cell cycle progression and tumorigenesis in breast cancer.

  5. B-Myb plays a role in suppression of keratinocyte differentiation and maintenance of the undifferentiated proliferative phenotype by modulating the expression levels of cell cycle regulatory proteins, expressed in the S and G2/M phases of the cell cycle

  6. Results show that E7 interacts with the B-Myb, FoxM1 (show FOXM1 ELISA Kits) and LIN9 (show LIN9 ELISA Kits) components of this activator complex, leading to cooperative transcriptional activation of mitotic genes in primary cells and E7 recruitment to the corresponding promoters.

  7. MYBL2 expression analysis could be useful to define subgroups of patients with poor prognosis.

  8. MALAT1-depleted cells display reduced expression of B-MYB (Mybl2), an oncogenic transcription factor involved in G2/M progression, due to altered binding of splicing factors on B-MYB pre-mRNA and aberrant alternative splicing

  9. Low MYBL2 expression is associated with haematopoietic neoplasia.

  10. A novel role for B-Myb in S-phase that appears to be independent of its sequence-specific DNA-binding activity and its ability to stimulate the expression of bona fide B-Myb target genes.

Cow (Bovine) V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) interaction partners

  1. B-Myb (MYBL2)repressor function is regulated by cyclin A (show CCNA2 ELISA Kits) phosphorylation and sequences within the C-terminal domain.

  2. B-Myb represses SMC (show DYM ELISA Kits) elastin (show ELN ELISA Kits) gene expression and cyclin A (show CCNA2 ELISA Kits) plays a role in the developmental regulation of elastin (show ELN ELISA Kits) gene expression in the aorta

MYBL2 Antigen Profile

Antigen Summary

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.

Alternative names and synonyms associated with MYBL2

  • v-myb myeloblastosis viral oncogene homolog (avian)-like 2 (MYBL2) Elisa Kit
  • v-myb myeloblastosis viral oncogene homolog-like 2 (mybl2) Elisa Kit
  • myeloblastosis oncogene-like 2 (mybl2) Elisa Kit
  • myeloblastosis oncogene-like 2 (Mybl2) Elisa Kit
  • v-myb avian myeloblastosis viral oncogene homolog-like 2 (MYBL2) Elisa Kit
  • v-myb avian myeloblastosis viral oncogene homolog-like 2 (mybl2) Elisa Kit
  • v-myb myeloblastosis viral oncogene homolog-like 2 (MYBL2) Elisa Kit
  • B-MYB Elisa Kit
  • BMYB Elisa Kit
  • myb1 Elisa Kit
  • MYBL2 Elisa Kit

Protein level used designations for MYBL2

v-myb myeloblastosis viral oncogene homolog (avian)-like 2 , myb-related protein B , v-myb myeloblastosis viral oncogene homolog-like 2 , MOL2 , b-myb , crash&burn , crb , myb-like protein 2 , B-Myb , XMYB1 , myb-related protein 1 , myeloblastosis oncogene-like 2

GENE ID SPECIES
458262 Pan troglodytes
694693 Macaca mulatta
100070694 Equus caballus
100126220 Xenopus (Silurana) tropicalis
445390 Danio rerio
296344 Rattus norvegicus
17865 Mus musculus
4605 Homo sapiens
398085 Xenopus laevis
477232 Canis lupus familiaris
510420 Bos taurus
396258 Gallus gallus
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