Browse our p107 Proteins (RBL1)

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Retinoblastoma-Like 1 (p107) Proteins (RBL1)
On are 7 Retinoblastoma-Like 1 (p107) (RBL1) Proteins from 4 different suppliers available. Additionally we are shipping p107 Antibodies (112) and p107 Kits (23) and many more products for this protein. A total of 147 p107 products are currently listed.
AW547426, CP107, fj58e06, p107, PRB1, wu:fj58e06
list all proteins Gene Name GeneID UniProt
RBL1 5933 P28749
RBL1 19650 Q64701
Rat RBL1 RBL1 680111  

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p107 Proteins (RBL1) by Origin

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More Proteins for p107 Interaction Partners

Human Retinoblastoma-Like 1 (p107) (RBL1) interaction partners

  1. The authors found that phosphorylation of residues S650 and S975 in p107 weakens the E2F4 (show E2F4 Proteins) transactivation domain binding.

  2. UL97 phosphorylates and inactivates the retinoblastoma protein-related p107 and p130 (show RBL2 Proteins) proteins

  3. Sequence analysis of the RB1 (show RB1 Proteins) gene detected a novel mutation in bilateral retinoblastoma.

  4. MAGE (show MAGEB10 Proteins)-A11 is a proto-oncogene (show RAB1A Proteins) whose increased expression in prostate cancer reverses retinoblastoma-related protein p107 from a transcriptional repressor to a transcriptional activator of the androgen receptor (show AR Proteins) and E2F1 (show E2F1 Proteins).

  5. Single nucleotide polymorphism in the ultraconserved elements of RBL1 gene is associated with recurrence in colorectal adenocarcinoma.

  6. Concomitant germline large cytogenetic 13q deletion and somatic mutations in the RB1 (show RB1 Proteins) gene in unilateral retinoblastoma.

  7. identification of a PP2A (show PPP2R4 Proteins) trimeric holoenzyme containing B55alpha (show PPP2R2A Proteins), which plays a major role in restricting the phosphorylation state of p107 and inducing its activation in human cells.

  8. regulation of expression of p130 (show RBL2 Proteins), p107 and E2F-4 (show E2F4 Proteins) in human cells

  9. suggests that the p107 N-terminus provides an interaction domain for transcription factors involved in cell cycle control

  10. report shows hypophosphorylation of the retinoblastoma family proteins induced by H2O2 was because of the activity of protein phosphatase 2A

Mouse (Murine) Retinoblastoma-Like 1 (p107) (RBL1) interaction partners

  1. Findings indicate that inactivation of the Rb family proteins (Rb, p107, and p130) in hematopoietic stem cells (HSCs) progressively impairs their homeostasis, which is rescued upon repression of suppressor of cytokine signaling 3 (show SOCS3 Proteins) protein (Socs3 (show SOCS3 Proteins)) expression in triple knockout (TKO (show MRPS12 Proteins)) HSCs.

  2. p107 is required for the efficient recruitment of an activating SWI (show SMARCA1 Proteins)/SNF (show SNRPA Proteins) chromatin-remodeling complex, an essential event in Alpl (show ALPL Proteins) induction.

  3. while p107 alone did not have an essential role in islet homeostasis, when combined with Rb deletion, its absence potentiated apoptosis of both alpha and beta cells resulting in glucose intolerance and diminished islet mass with ageing

  4. Findings indicate that retinoblastoma-like protein p107 expression in stem cells commits cells to the white versus brown adipose lineage.

  5. p107 retinoblastoma protein is regulated by Cdk6 (show CDK6 Proteins)/Ccnd1 (show CCND1 Proteins) in growth plates.

  6. results reveal an overlapping role for pRB (show PGR Proteins) and p107 in cartilage development, endochondral ossification and enchondroma formation that reflects their coordination of cell-cycle exit at appropriate developmental stages

  7. Rb, p107 and p130 epigenetically protect newly born cortical neurons from DNA damage and cell division

  8. Data show that p21Cip1 (show CDKN1A Proteins) inactivation increases proliferation in Rb/p107DKO retina

  9. Mutation of p107 or p130 reduces survival of Rb-deficient myoblasts during differentiation.

  10. Data show that p107-deficient muscle expresses increased levels of peroxisome proliferator-activated receptor gamma co-activator-1alpha and contains increased numbers of the pro-oxidative type I and type IIa myofibers.

p107 (RBL1) Protein Profile

Protein Summary

The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with p107 (RBL1)

  • retinoblastoma-like 1 (p107) (rbl1)
  • retinoblastoma-like 1 (p107) (RBL1)
  • retinoblastoma-like 1 (p107) (Rbl1)
  • AW547426 protein
  • CP107 protein
  • fj58e06 protein
  • p107 protein
  • PRB1 protein
  • wu:fj58e06 protein

Protein level used designations for RBL1

retinoblastoma-like 1 (p107) , retinoblastoma-like protein 1 , retinoblastoma-like protein 1-like , 107 kDa retinoblastoma-associated protein , cellular protein 107

431930 Xenopus laevis
701650 Macaca mulatta
735916 Pan troglodytes
795522 Danio rerio
100216140 Xenopus (Silurana) tropicalis
100367775 Saccoglossus kowalevskii
100539013 Meleagris gallopavo
100560057 Anolis carolinensis
100599163 Nomascus leucogenys
5933 Homo sapiens
19650 Mus musculus
680111 Rattus norvegicus
477221 Canis lupus familiaris
524870 Bos taurus
419126 Gallus gallus
100342365 Oryctolagus cuniculus
100153296 Sus scrofa
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