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Browse our PLK1 (PLK1) ELISA Kits

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Polo-Like Kinase 1 ELISA Kits (PLK1)
On are 11 Polo-Like Kinase 1 (PLK1) ELISA Kits from 6 different suppliers available. Additionally we are shipping PLK1 Antibodies (342) and and many more products for this protein. A total of 381 PLK1 products are currently listed.
0256/04, 1324/08, anon-WO0172774.3, cb525, cb636, CG12306, Dmel\CG12306, ik:tdsubc_2d1, l(3)01673, l(3)77Aa, l(3)S025604, l(3)S132408, Plk, PLK-1, PLK1, Plx1, Polo, POLO/PLK1, Polo kinase, Snk, STPK13, wu:fb37g11, wu:fb76g03, xx:tdsubc_2d1

More ELISA Kits for PLK1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Polo-Like Kinase 1 (PLK1) interaction partners

  1. Polo is an important in vivo regulator of the pathological functions of APP (show APP ELISA Kits).

  2. Both conditions impaired NSC lineage progression. Ca(2 (show CA2 ELISA Kits)) mito homeostasis is influenced by Polo-mediated phosphorylation of a conserved residue in Miro

  3. During pericentriolar matrix formation exon 1A Cnn-Long Form proteins likely bind Polo kinase before phosphorylation by Polo for Cnn transport to the centrosome.

  4. Polo kinase is required for localization and activity of the chromosomal passenger complex in mitosis and meiosis.

  5. Centrioles, which usually separate during the anaphase of the first meiosis, remained held together in a V-shaped configuration suggesting that Polo kinase regulates the proteolysis that breaks centriole linkage to ensure their disengagement.

  6. Results show that Polo kinase positively and negatively regulates Augmin distribution for microtubule nucleation and acentrosomal spindle formation.

  7. Regulation of Polo by Aurora B (show AURKB ELISA Kits) and Map205 is required for cytokinesis.

  8. These data indicate APC (show APC ELISA Kits)(Cort (show CORT ELISA Kits)) ubiquitylates Mtrm at the oocyte-to-embryo transition, thus preventing excessive inhibition of Polo kinase activity due to Mtrm's presence.

  9. a model in which Polo controls Mps1-dependent BubR1 (show BUB1B ELISA Kits) phosphorylation to promote Cdc20 (show CDC20 ELISA Kits) kinetochore recruitment and sustained SAC (show ADCY10 ELISA Kits) function.

  10. Data indicate that interphase centrioles are closely associated with Sas-4, Spd-2, Polo kinase, Pericentrin-like protein (Dplp (show PCNT ELISA Kits)), Asterless (Asl (show ADSL ELISA Kits)), Plk4 (show PLK4 ELISA Kits) kinase, Centrosomin (show EIF3A ELISA Kits) (Cnn) and gamma-tubulin (show TUBG1 ELISA Kits).

Xenopus laevis Polo-Like Kinase 1 (PLK1) interaction partners

  1. Novel roles for Plk and GSK3 regulation of ADAM13 (show ADAM33 ELISA Kits) function in cranial neural crest cell migration.

  2. Plx1-mediated degradation of Bora in interphase generates oscillations in Plx1 activity and is essential for development.

  3. Coordinated interplays between Plx1 and Gwl (show MASTL ELISA Kits) are required for reactivation of these kinases from the G(2)/M DNA damage checkpoint and efficient checkpoint recovery.

  4. the penultimate CRS (show CARS ELISA Kits) serine (Ser (show SIGLEC1 ELISA Kits) 101) of cyclin b1 (show CCNB1 ELISA Kits) is a Plx substrate

  5. Results suggest that polo-like kinase (Plx1) could be the missing regulator that prevents maturation-promoting factor autoamplification in stage IV oocytes.

  6. Plx1 cooperates with CaMKII (show CAMK2G ELISA Kits) to regulate cyclosome regulators, and is necessary for release of cytostatic factor metaphase arrest and sufficient when overexpressed.

  7. Data show that Plx1 couples tension signals to cellular responses through phosphorylation of the 3F3 (show TRIM32 ELISA Kits)/2 epitope and targeting structural and checkpoint proteins to kinetochores.

  8. Polo-like kinase Plx1 is an essential factor for calcium ion-induced meiotic exit during cytostatic factor arrest

  9. Polo-like kinase (Plx1) phosphorylates xTRF1 in vitro and the mitotic xTRF1-chromatin association was significantly impaired when Plx1 was immunodepleted from the extracts (Plx1).

  10. Cdk1 (show CDK1 ELISA Kits) phosphorylation of BubR1 (show BUB1B ELISA Kits) controls spindle checkpoint arrest and plk-mediated formation of the 3F3 (show TRIM32 ELISA Kits)/2 epitope.

Human Polo-Like Kinase 1 (PLK1) interaction partners

  1. The Plk1 at the kinetochore is a conglomerate of an observable bulk pool coupled with additional functional pools below the threshold of microscopic detection or resolution.

  2. Human embryonic kidney 293 cell and mesenchymal stem cell exosomes were effectively used as a delivery vector to transport PLK-1 siRNA to bladder cancer cells in vitro, resulting in selective gene silencing of PLK-1.

  3. Analysis of key players in cell cycle control revealed that low nanomolar concentrations of either polo-like kinase 1 inhibitor upregulated cyclin B1 (show CCNB1 ELISA Kits) and increased activated cyclin-dependent kinase 1 (show CDK1 ELISA Kits) (phosphorylated at Y15) in retinoblastoma cell lines.

  4. This study demonstrated that PLK1-associated microRNAs are correlated with pediatric medulloblastoma.

  5. PLK1 is inhibited by BI 2536 and GSK461364 in tumor cells

  6. High PLK1 expression is associated with acute myeloid leukemia (show BCL11A ELISA Kits).

  7. Decreased Plk1 expression was associated with poor pathologic response and worse disease-free survival in rectal cancer patients receiving neoadjuvant chemoradiotherapy

  8. Plk1 inhibition can lead to cancer cell apoptosis through inactivating XIAP (show XIAP ELISA Kits), activating caspase-3 (show CASP3 ELISA Kits), upregulating BAX (show BAX ELISA Kits) and downregulating Bcl-2 (show BCL2 ELISA Kits).

  9. Moreover, PLK1 activity is important for FOXC2 (show FOXC2 ELISA Kits) protein stability, since PLK1 inhibition reduces FOXC2 (show FOXC2 ELISA Kits) protein levels.

  10. Authors provide clinical evidence that high expression of PLK1 could have detrimental effects in tumors with DNA aneuploidy, which may increase the risk of recurrence in gastric cancer patients.

Pig (Porcine) Polo-Like Kinase 1 (PLK1) interaction partners

  1. PLK1 might play a critical role in vascular smooth muscle cell mitosis in hyperplastic intima of the injured vessels.

  2. Data show that Polo-like kinase 1 is activated before M phase promoting factor (MPF (show MSLN ELISA Kits)), which is consistent with its role in activating MPF (show MSLN ELISA Kits) in mammalian oocytes.

Mouse (Murine) Polo-Like Kinase 1 (PLK1) interaction partners

  1. Results indicate that polo-like kinase 1 (PLK1) controls the onset of spindle assembly and spindle formation, and is essential for anaphase-promoting complex/cyclosome (APC (show APC ELISA Kits)/C) activation before anaphase onset in zygotes.

  2. observations revealed that the alteration of PKB-GSK-3beta axis, Plk-1, and Aurora kinase-A expressions in HSPC compartment due to DNA damage response was associated with the proliferative impairment and apoptosis during aplastic anemia.

  3. Plk1 activity is required for meiotic spindle assembly and REC8 (show REC8 ELISA Kits) cleavage, with pPlk1Ser137 being the action executor, in mouse oocytes during meiotic division.

  4. Augmented expression of Aurora kinase-A (show AURKA ELISA Kits) and Polo-like kinase-1 at the lactogenic switch likely mediates the formation of binucleated cells.

  5. Combined Plk1-HDAC (show HDAC3 ELISA Kits) inhibition reduces survival in Hela cells but not in non-cancer cells.

  6. PLK1 is required for the full activation of the anaphase promoting complex/cyclosome, for proper chromosome segregation and the maintenance of chromosome condensation during the meiosis I-II transition.

  7. we show here that Polo-like kinase 1 (Plk1) is required for endomitosis, and ablation of the Plk1 gene in megakaryocytes results in defective polyploidization accompanied by mitotic arrest and cell death

  8. PLK1 protein levels are increased in hamartin (show TSC1 ELISA Kits) and tuberin (show TSC2 ELISA Kits) deficient cells and Lymphangioleiomyomatosis patient-derived specimens, and that this increase is rapamycin-sensitive.

  9. Plk1 as an important regulator of PTEN during the cell cycle

  10. Results show that Plk1 phosphorylation of PTEN promotes tumorigenesis.

Zebrafish Polo-Like Kinase 1 (PLK1) interaction partners

  1. Report the 2.3-A crystal structure of the complex of the N-terminal kinase domain (KD) and a C-terminal Polo-box domain (PBD together with a PBD-binding motif of Drosophila melanogaster microtubule-associated protein (show FAM82A2 ELISA Kits) 205 (Map205(PBM)).

  2. Studies demonstrate that Plk1 is required for embryonic proliferation because its activity is crucial for mitotic integrity.

  3. for the first time that Plk1 can accommodate extended ATP-competitive compounds that project toward the adaptive pocket and help the enzyme order its activation segment

Caenorhabditis elegans (C. elegans) Polo-Like Kinase 1 (PLK1) interaction partners

  1. These results reveal a crucial and conserved role of phosphorylation of the N terminus of Bora for Plk1 activation and mitotic entry.

  2. Our data further show that PLK-1 is needed for nuclear envelope breakdown during early embryogenesis

  3. PLK-1 substitutes for Mps1 in controlling spindle checkpoint initiation in C. elegans.

  4. NCAPG2 (show NCAPG2 ELISA Kits) plays an important role in regulating proper chromosome segregation through a functional interaction with PLK1 during mitosis

  5. CDK-1 (show CDK1 ELISA Kits) activates PLK-1 via SPAT (show AGXT ELISA Kits)-1 phosphorylation to promote entry into mitosis.

  6. The result provide key insights into the regulation of homolog pairing and reveal that targeting of plk-1 to the NE by meiotic chromosomes establishes the conserved linkages to cytoskeletal forces needed for homology assessment.

  7. SPAT (show AGXT ELISA Kits)-1 and PLK-1 depletion causes impaired polarity with abnormal length of the anterior and posterior PAR (show AFG3L2 ELISA Kits) domains, and partial plk-1(RNAi) or spat (show AGXT ELISA Kits)-1(RNAi), but not air-1(RNAi), can rescue the lethality of a par-2 (show F2RL1 ELISA Kits) mutant.

  8. Polo kinases, via their polo box domains, bind to and regulate the activity of two key polarity proteins, MEX-5 and MEX-6.

  9. plk-1 asymmetry contributes to asynchronous cell division in C. elegans embryos.

  10. We suggest that control of Plk1 and Cdc25 (show CDC25C ELISA Kits) may be relevant to regulation of cell cycle length in other developmental contexts.

PLK1 Antigen Profile

Antigen Summary

human homolog catalyzes the phosphorylation of a Golgi reassembly stacking protein (GRASP65); may play a role in Golgi apparatus fragmentation and reorganization during mitosis

Alternative names and synonyms associated with PLK1

  • polo-like kinase 1 (plk1) Elisa Kit
  • CG12306 gene product from transcript CG12306-RA (polo) Elisa Kit
  • polo-like kinase 1 (PLK1) Elisa Kit
  • polo-like kinase 1 (Plk1) Elisa Kit
  • polo-like kinase 1 (Drosophila) (plk1) Elisa Kit
  • polo-like kinase 2 (Plk2) Elisa Kit
  • Protein PLK-1 (plk-1) Elisa Kit
  • 0256/04 Elisa Kit
  • 1324/08 Elisa Kit
  • anon-WO0172774.3 Elisa Kit
  • cb525 Elisa Kit
  • cb636 Elisa Kit
  • CG12306 Elisa Kit
  • Dmel\CG12306 Elisa Kit
  • ik:tdsubc_2d1 Elisa Kit
  • l(3)01673 Elisa Kit
  • l(3)77Aa Elisa Kit
  • l(3)S025604 Elisa Kit
  • l(3)S132408 Elisa Kit
  • Plk Elisa Kit
  • PLK-1 Elisa Kit
  • PLK1 Elisa Kit
  • Plx1 Elisa Kit
  • Polo Elisa Kit
  • POLO/PLK1 Elisa Kit
  • Polo kinase Elisa Kit
  • Snk Elisa Kit
  • STPK13 Elisa Kit
  • wu:fb37g11 Elisa Kit
  • wu:fb76g03 Elisa Kit
  • xx:tdsubc_2d1 Elisa Kit

Protein level used designations for Polo-Like Kinase 1 (PLK1) ELISA Kits

serine/threonine-protein kinase PLK1 , CG12306-PA , CG12306-PB , polo kinase , polo protein kinase , polo-PA , polo-PB , PLK-1 , plx1 , cell cycle regulated protein kinase , polo (Drosophia)-like kinase , polo like kinase , serine/threonine-protein kinase 13 , polo-like protein kinase , polo-like kinase homolog , PLK-2 , polo-like kinase 1 , serine/threonine-protein kinase PLK2 , serine/threonine-protein kinase SNK , serum-inducible kinase

407937 Xenopus (Silurana) tropicalis
40232 Drosophila melanogaster
380481 Xenopus laevis
416575 Gallus gallus
453991 Pan troglodytes
5347 Homo sapiens
489971 Canis lupus familiaris
396953 Sus scrofa
18817 Mus musculus
25515 Rattus norvegicus
538238 Bos taurus
280649 Danio rerio
83722 Rattus norvegicus
176143 Caenorhabditis elegans
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