Browse our Glutaredoxin Proteins (GLRX)

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Glutaredoxin Proteins (GLRX)
On www.antibodies-online.com are 8 Glutaredoxin (GLRX) Proteins from 4 different suppliers available. Additionally we are shipping Glutaredoxin Antibodies (26) and Glutaredoxin Kits (8) and many more products for this protein. A total of 43 Glutaredoxin products are currently listed.
Synonyms:
C86710, D13Wsu156e, Glrx1, GRX, GRX1, TTase
list all proteins Gene Name GeneID UniProt
GLRX 93692 Q9QUH0
Rat GLRX GLRX 64045 Q9ESH6
GLRX 2745 P35754

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Glutaredoxin Proteins (GLRX) by Origin

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More Proteins for Glutaredoxin Interaction Partners

Mouse (Murine) Glutaredoxin (GLRX) interaction partners

  1. Study reports a decrease of Grx (show GRX1 Proteins) expression levels in pancreatic islets of diabetic mice which was accompanied by declining insulin (show INS Proteins) secretion, increase of reactive oxygen species (ROS (show ROS1 Proteins)) production level, and cell cycle alterations. These data demonstrate the essential role of the Grx (show GRX1 Proteins) system for the beta-cell during metabolic stress which may provide a new target for diabetes mellitus type 2 treatment.

  2. Our results indicate that Grx1 (show GRX1 Proteins) upregulation promotes neuroinflammation and consequent neuronal cell death in vitro, and synergizes with proinflammatory insults to promote DA loss in vivo.

  3. the Glrx1 (show GRX1 Proteins)-Protein S-glutathionylation axis plays a pivotal role in house dust mite-induced allergic airways disease.

  4. Glrx (show GRX1 Proteins) ablation stabilizes HIF-1alpha (show HIF1A Proteins) by increasing GSH adducts on Cys (show DNAJC5 Proteins)(520) promoting in vivo HIF-1alpha (show HIF1A Proteins) stabilization, VEGF-A (show VEGFA Proteins) production, and revascularization in the ischemic muscles.

  5. Prx2 (show PRRX2 Proteins) glutathionylation is a favorable reaction that can occur in cells under oxidative stress and may have a role in redox signaling. GSH/Grx1 (show GRX1 Proteins) provide an alternative mechanism to thioredoxin (show TXN Proteins) and thioredoxin reductase (show PRDX2 Proteins) for Prx2 (show PRRX2 Proteins) recycling.

  6. The temporal relationships of Glrx1 (show GRX1 Proteins) with protein S-glutathionylation, glutathione, and cytokines/chemokines were observed as dynamic changes in lungs with allergic airway inflammation

  7. Glutaredoxin 1 (show GRX1 Proteins) plays an important role in controlling epithelial cell responsiveness to IL-17A (show IL17A Proteins)

  8. Up-r (show GRX1 Proteins)egulated Glrx inhibits VEGF signaling by increa (show FLT1 Proteins)sed Flt1 causing impaired vascularization.

  9. S-glutathionylation of Fas (show FAS Proteins) in lung epithelium enhances epithelial apoptosis and clearance of P. aeruginosa. Glutaredoxin-1 (show GRX1 Proteins) impairs bacterial clearance and increases severity of pneumonia in association with deglutathionylation of Fas (show FAS Proteins).

  10. These data suggest that the overexpression of GRX1 (show GRX1 Proteins) could protect cardiomyocytes against NO-induced apoptosis, likely through the inhibition of the oxidative modification and the nuclear translocation of GAPDH (show GAPDH Proteins).

Human Glutaredoxin (GLRX) interaction partners

  1. Our results indicate that Grx1 (show GRX1 Proteins) upregulation promotes neuroinflammation and consequent neuronal cell death in vitro, and synergizes with proinflammatory insults to promote DA loss in vivo.

  2. Glutaredoxin (show GRX1 Proteins) desensitizes lens to oxidative stress by connecting and integrating specific signaling and transcriptional regulation for antioxidant response.

  3. Glrx (show GRX1 Proteins) ablation stabilizes HIF-1alpha (show HIF1A Proteins) by increasing GSH adducts on Cys (show DNAJC5 Proteins)(520) promoting in vivo HIF-1alpha (show HIF1A Proteins) stabilization, VEGF-A (show VEGFA Proteins) production, and revascularization in the ischemic muscles.

  4. The results demonstrate that the antiproliferative effect of NO is hampered by Trx1 (show MLL Proteins) and Grx1 (show GRX1 Proteins) and support the strategy of weakening the thiolic antioxidant defenses when designing new antitumoral therapies.

  5. Prx2 (show PRDX2 Proteins) glutathionylation is a favorable reaction that can occur in cells under oxidative stress and may have a role in redox signaling. GSH/Grx1 (show GRX1 Proteins) provide an alternative mechanism to thioredoxin (show TXN Proteins) and thioredoxin reductase (show PRDX5 Proteins) for Prx2 (show PRDX2 Proteins) recycling.

  6. Glutaredoxin 1 (show GRX1 Proteins) protects human retinal pigment epithelial cells from oxidative damage by preventing AKT (show AKT1 Proteins) glutathionylation.

  7. A new function for GRX1 (show GRX1 Proteins) in neuronal copper homeostasis and in protection from copper-mediated oxidative injury.

  8. Human Grx1 (show GRX1 Proteins) can catalyse reduction of Atox1 (show ATOX1 Proteins) by glutathione but only in the presence of Cu(I).

  9. Levels of GLRX (show GRX1 Proteins) in the cerebrospinal fluid increase significantly in the early stages of Alzheimer's disease.

  10. Glrx (show GRX1 Proteins) overexpression increased soluble VEGF receptor (show FLT1 Proteins) 1 (sFlt) in endothelial cells via NF-kappaB (show NFKB1 Proteins)-dependent Wnt5a (show WNT5A Proteins) production.

Glutaredoxin (GLRX) Protein Profile

Protein Summary

This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Alternative names and synonyms associated with Glutaredoxin (GLRX)

  • glutaredoxin (Glrx)
  • glutaredoxin (thioltransferase) (Glrx)
  • glutaredoxin (thioltransferase) (GLRX)
  • C86710 protein
  • D13Wsu156e protein
  • Glrx1 protein
  • GRX protein
  • GRX1 protein
  • TTase protein

Protein level used designations for Glutaredoxin Proteins (GLRX)

TTase-1 , glutaredoxin (thioltransferase) , glutaredoxin 1 (thioltransferase) , glutaredoxin-1 , thioltransferase-1

GENE ID SPECIES
93692 Mus musculus
64045 Rattus norvegicus
2745 Homo sapiens
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