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Self-interaction of the transmembrane helix of QSOX2 rests on a motif of conserved amino acids compromising one face of the helix.
The present study was unable to confirm a significant association of all of the three SNPs, rs12338076 in LHX3 (show LHX3 ELISA Kits)-QSOX2, and rs1457595 and rs17032362 in IGF1 (show IGF1 ELISA Kits), with adult height in our study population.
Results identify SOXN as a major player in Regulating the sensitization of neuroblastoma (show ARHGEF16 ELISA Kits) cells for IFN-gamma-induced (show SAMHD1 ELISA Kits) apoptosis.
QSOX2 is a member of the sulfhydryl oxidase/quiescin-6 (Q6) family (QSOX1\; MIM 603120) that regulates the sensitization of neuroblastoma cells for IFN-gamma (IFNG\; MIM 147570)-induced cell death (Wittke et al., 2003
quiescin Q6 sulfhydryl oxidase 2
, quiescin Q6-like 1
, sulfhydryl oxidase 2
, quiescin Q6-like protein 1
, sulfhydryl oxidase 2-like
, neuroblastoma-derived sulfhydryl oxidase