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The patients with advanced-stagemalignant pleural mesothelioma (MPM) showed higher levels of TRX (show VAC14 Proteins) than those with early-stage MPM.
spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity
Txndc2 and Txndc3 (show TXNDC3 Proteins) are critically important in protecting spermatozoa against the increases in oxidative stress associated with paternal age.
Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase (By similarity).
sperm-specific thioredoxin 1
, spermatid-specific thioredoxin-1
, thioredoxin domain-containing 2 (spermatozoa)
, thioredoxin domain-containing protein 2
, spermatid-specific thioredoxin 1