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TXNDC5 is also closely associated with rheumatoid arthritis, diabetes, hepatic steatosis and vitiligo (show MITF ELISA Kits). [review]
High TXNDC5 expression is associated with renal cell carcinoma.
we defined an important role of TXNDC5 in CRPC and further investigations are needed to screen TXNDC5 antagonists as a novel therapeutic approaches to treat PCa (show FLVCR1 ELISA Kits) patients with Castration-resistant prostate cancer.
Role of ERp46 in oxidative protein folding.Independent actions of ERp46 thioredoxin domains on folding substrates.Structure of thioredoxin ERp46 domains.
suggest that the tumorigenic properties of ERp46 in RCC (show XRCC1 ELISA Kits) cells are not related to an inhibitory modulation of AdipoR1 (show ADIPOR1 ELISA Kits)
Endo-PDI (show PADI1 ELISA Kits) is a novel, important mediator of AP-1 (show FOSB ELISA Kits)-driven gene expression and endothelial angiogenic function.
TXNDC5 has increased expression in many tumors that is involved in the proliferation and migration of tumor cells, acting as a tumor-enhancing gene.
results suggest that TXNDC5 polymorphisms could be related to the development of HCC (show FAM126A ELISA Kits) in the Korean male population
Hyperoxidized peroxiredoxin 2 interacts with the protein disulfide- isomerase ERp46.
Hypoxia induced TXCNDC5 expression, which contributed to adiponectin (show ADIPOQ ELISA Kits) expression, cytokine production and the cellular proliferation and migration of fibroblasts in rheumatoid arthritis.
Txndc5 reflects the anti-steatotic properties of squalene and the sensitivity to lipid accumulation.
ERp46 plays a protective role in palmitic acid -induced cell apoptosis by decreasing the endoplasmic reticulum stress response and might be a novel target for anti-diabetic drugs.
Potential role for TXNDC5 in resistance to nitrosative stress.
both ERp19 and ERp46 and their respective mRNAs are highly expressed in the liver as compared with other tissues
PC-TRP was expressed at high levels in all plasma cells isolated from bone marrow or lamina propria.
ERp46 may be an important component in the phenomenon of "glucose toxicity" involved in insulin (show INS ELISA Kits) production at the posttranslational level.
This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene.
ER protein 46
, endoplasmic reticulum protein ERp46
, endoplasmic reticulum resident protein 46
, endothelial protein disulphide isomerase
, protein disulfide isomerase family A, member 15
, thioredoxin domain-containing protein 5
, thioredoxin related protein
, thioredoxin-like protein p46
, plasma cell-specific thioredoxin-related protein
, protein disulfide isomerase
, thioredoxin domain containing 5
, thioredoxin domain containing 5 (endoplasmic reticulum)
, thioredoxin domain containing protein 5