Browse our Histone Deacetylase 8 (HDAC8) ELISA Kits

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Histone Deacetylase 8 ELISA Kits (HDAC8)
On are 15 Histone Deacetylase 8 (HDAC8) ELISA Kits from 9 different suppliers available. Additionally we are shipping Histone Deacetylase 8 Antibodies (164) and Histone Deacetylase 8 Proteins (24) and many more products for this protein. A total of 218 Histone Deacetylase 8 products are currently listed.
2610007D20Rik, ATHDA8, CDLS5, HD8, HDA8, HDACL1, histone deacetylase 8, MRXS6, RGD1562895, RPD3, T27G7.14, T27G7_14, WTS, wu:fd19a02, zgc:66196
list all ELISA KIts Gene Name GeneID UniProt
HDAC8 55869 Q9BY41
HDAC8 70315 Q8VH37
HDAC8 363481 B1WC68

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Histone Deacetylase 8 (HDAC8) ELISA Kits by Reactivity

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More ELISA Kits for Histone Deacetylase 8 Interaction Partners

Human Histone Deacetylase 8 (HDAC8) interaction partners

  1. 7-amino-4-methylcoumarin did not affect acetyllysine preference in a multiply acetylated substrate. In contrast, AMC significantly enhanced KDAC6 substrate affinity, greatly reduced Sirt1 (show SIRT1 ELISA Kits) activity, eliminated the substrate sequence specificity of KDAC4, and had no consistent effect with KDAC8 substrates.

  2. Enzymological, biophysical, and structural studies of Cornelia de Lange Syndrome HDAC8 protein mutants have yielded critical insight on compromised catalysis in vitro. Most CdLS (show NIPBL ELISA Kits) HDAC8 mutations trigger structural changes that directly or indirectly impact substrate binding and catalysis.

  3. class I HDACs (HDAC1 (show HDAC1 ELISA Kits), 2, 3 and 8) play a major role in regulating extracellular matrix and Epithelial-mesenchymal transition, whereas class IIa HDACs (HDAC4 (show HDAC4 ELISA Kits) and 5) are less effective.

  4. Losses of catalytic efficiency in histone deacetylase 8 (HDAC8) are observed for G304A and G305A mutations.

  5. Data suggest sequencing of histone deacetylase 8 protein (HDAC8) as an indispensable part of the routine molecular diagnostic for patients with Cornelia de Lange syndrome (CdLS (show NIPBL ELISA Kits)) or CdLS (show NIPBL ELISA Kits)-overlapping features.

  6. HDAC8 were overexpressed in oral squamous cell carcinoma tissues, mainly localized in the cytoplasm.

  7. Study reveals that HDAC8 can bind and catalyze deacetylation of many acetylated peptides with sequences corresponding to cellular, non-histone proteins, thereby opening a new window to the functional role of HDAC8 in cells.

  8. Findings suggest the therapeutic potential of histone deacetylase 8 histone (HDAC8)inhibition to suppress Notch1 (show NOTCH1 ELISA Kits) signaling in breast cancer.

  9. Data show that histone deacetylase 8 (HDAC8) inhibition led to accumulation of acetylated-SMC3 (show SMC3 ELISA Kits) protein but had no influence on the transcription of estrogen-responsive genes.

  10. study elucidates an HDAC8-mediated p53 (show TP53 ELISA Kits)-inactivating mechanism promoting leukemia stem cells activity

Mouse (Murine) Histone Deacetylase 8 (HDAC8) interaction partners

  1. this study demonstrates a novel role of HDAC8 in LeTx immunotoxicity and regulation of pro-IL-1beta (show IL1B ELISA Kits) production likely through eRNAs.

  2. findings show how HDAC8 drives nonalcoholic fatty liver disease-associated hepatocarcinogenesis

  3. Data reveal a role for miR (show MLXIP ELISA Kits)-21-3p in regulating HDAC8 expression and Akt (show AKT1 ELISA Kits)/Gsk3beta (show GSK3b ELISA Kits) pathway in cardiac hypertrophy.

  4. histone deacetylase 8 inhibition reduces gene expression and production of proinflammatory cytokines in vitro and in vivo

  5. HDAC8 and Sirt1 (show SIRT1 ELISA Kits) were also demonstrated to interact directly with ERRalpha (show ESRRA ELISA Kits) in vivo and to deacetylate and increase the DNA binding affinity of ERRalpha (show ESRRA ELISA Kits) in vitro.

  6. Global deletion of Hdac8 in mice leads to perinatal lethality due to skull instability, and deletion of Hdac8 in cranial neural crest cells and Hdac8 specifically represses the aberrant expression of homeobox (show PRRX1 ELISA Kits) transcription factors such as Otx2 (show OTX2 ELISA Kits) and Lhx1 (show LHX1 ELISA Kits)

Histone Deacetylase 8 (HDAC8) Antigen Profile

Antigen Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Histone Deacetylase 8 (HDAC8)

  • histone deacetylase 8 (CC1G_05302) Elisa Kit
  • histone deacetylase 8 (hdac8) Elisa Kit
  • histone deacetylase 8 (HDAC8) Elisa Kit
  • histone deacetylase 8 (Hdac8) Elisa Kit
  • histone deacetylase 8 (HDA08) Elisa Kit
  • 2610007D20Rik Elisa Kit
  • ATHDA8 Elisa Kit
  • CDLS5 Elisa Kit
  • HD8 Elisa Kit
  • HDA8 Elisa Kit
  • HDACL1 Elisa Kit
  • histone deacetylase 8 Elisa Kit
  • MRXS6 Elisa Kit
  • RGD1562895 Elisa Kit
  • RPD3 Elisa Kit
  • T27G7.14 Elisa Kit
  • T27G7_14 Elisa Kit
  • WTS Elisa Kit
  • wu:fd19a02 Elisa Kit
  • zgc:66196 Elisa Kit

Protein level used designations for HDAC8

histone deacetylase 8 , histone deacetylase-like 1 , HD8

6017058 Coprinopsis cinerea okayama7130
100145561 Xenopus (Silurana) tropicalis
55869 Homo sapiens
70315 Mus musculus
363481 Rattus norvegicus
406740 Danio rerio
444137 Xenopus laevis
540666 Bos taurus
480957 Canis lupus familiaris
422182 Gallus gallus
100721893 Cavia porcellus
837366 Arabidopsis thaliana
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