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Activation-Induced Cytidine Deaminase ELISA Kits (AICDA)
On www.antibodies-online.com are 2 Activation-Induced Cytidine Deaminase (AICDA) ELISA Kits from 2 different suppliers available. Additionally we are shipping AICDA Antibodies (114) and AICDA Proteins (11) and many more products for this protein. A total of 134 AICDA products are currently listed.
Synonyms:
4921510D23Rik, AA409782, AICDA, Aid, Arp2, CDA2, D6Ertd746e, HIGM2, xlaid
list all ELISA KIts Gene Name GeneID UniProt
AICDA 57379 Q9GZX7
Mouse AICDA AICDA 11628 Q9WVE0
Rat AICDA AICDA 399679  

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AICDA (AICDA) ELISA Kits by Reactivity

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Xenopus laevis Activation-Induced Cytidine Deaminase (AICDA) interaction partners

  1. Features of activation-induced deaminase (AID) mapping within the noncatalytic domain, but outside the chromosome region maintenance 1-dependent nuclear export signal at the C-terminus, influence its function.

Human Activation-Induced Cytidine Deaminase (AICDA) interaction partners

  1. silencing of AID in human bone marrow cells skews differentiation toward myelomonocytic lineage. However, in contrast to Tet2 loss, Aid loss does (show CEBPA ELISA Kits) not contr (show GATA1 ELISA Kits)ibute to enhanced HSC self-renewal or cooperate with Flt3-ITD to induce myeloid transformation. Genome-wide transcription and differential methylation analysis uncover the critical role of Aid as a key epigenetic regulator

  2. These findings indicated that TNF-alpha (show TNF ELISA Kits)-induced AID expression is involved with class switch recombination in cancer.

  3. Finnish founder allele causing HIGM2 identified.

  4. this study reports a case of growth hormone (show GH1 PLURAL_@44952@) deficiency with an autosomal recessive Hyper-immunoglobulin M syndrome by phenotype and genotype, with a novel mutation in AICDA that has not been reported formerly

  5. AICDA/APOBEC family of cytidine deaminases is significant in innate immunity, as it restricts numerous viruses, including HBV, through hypermutationdependent and independent mechanisms. (Review)

  6. DNA methylation (show HELLS ELISA Kits) dynamics of germinal center B cells are mediated by AID.

  7. Mutations in activation-induced cytidine deaminase is associated with indolent chronic lymphocytic leukaemia.

  8. Data suggest novel mechanism in innate immunity allows cytokine TGF-beta (show TGFB1 ELISA Kits) to restrict viral circular DNA in hepatocyte nuclei via innate immunity; AID deaminates circular DNA of hepatitis B virus leading to DNA degradation; mechanism depends on UNG (show UNG ELISA Kits).

  9. The high levels of memory and activated B cells and follicular helper T cells were positively associated with the progression of immunoglobulin A nephropathy. This may be mediated by the overexpression of AID, which is potentially regulated by IL21 (show IL17C ELISA Kits).

  10. High expression of activation-induced cytidine deaminase is associated with diffuse large B cell lymphoma.

Mouse (Murine) Activation-Induced Cytidine Deaminase (AICDA) interaction partners

  1. The reduced expression of activation-induced cytidine deaminase (AID).

  2. this study shows that enforced expression of Sox2 in splenic B cells severely inhibits AID expression and IgH class switch recombination

  3. Aid loss in mice leads to expansion of myeloid cells and reduced erythroid progenitors resulting in anemia, with dysregulated expression of Cebpa (show CEBPA ELISA Kits) and Gata1 (show GATA1 ELISA Kits), myeloid/erythroid lineage-specific transcription factors

  4. UNG (show UNG ELISA Kits) deficiency reduces B cell clonal expansion in the germinal center in mice and blocks the proliferation of tumor B cells expressing AID.

  5. We find that the expression of the actin polymerization complex Arp2/3 is reduced in dysbindin-deficient cells, thus affecting actin-dependent phenotypes

  6. Arp2 and Arp3 (show ANGPTL6 ELISA Kits) expression was increased under atherosclerotic conditions both in ApoE (show APOE ELISA Kits)-/- mice and in oxidized low-density lipoproteins stimulated human coronary artery endothelial cells (HCAECs).

  7. Efficient chemoprotection of CDD (show CDA ELISA Kits) and MDR1 (show ABCB4 ELISA Kits) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (show FOXC1 ELISA Kits)-C and anthracycline application

  8. Dendritic cells possess a mechanism to pass through micrometric constrictions. This mechanism is based on a rapid Arp2/3-dependent actin nucleation around the nucleus that disrupts the nuclear lamina, the main structure limiting nuclear deformability.

  9. DNA methylation (show HELLS ELISA Kits) dynamics of germinal center B cells are mediated by AID.

  10. demonstrate that the Arp2/3 complex in higher eukaryotes is actually a family of complexes with different properties

Cow (Bovine) Activation-Induced Cytidine Deaminase (AICDA) interaction partners

  1. crystal structure of Arp2 (show ACTR2 ELISA Kits)/3 complex

  2. These results demonstrate an important role for CRMP-1 (show CRMP1 ELISA Kits) in Listeria actin comet tail formation and open the possibility that CRMP-1 (show CRMP1 ELISA Kits) controls cell motility by modulating Arp2 (show ACTR2 ELISA Kits)/3 activation.

  3. TET3 (show TET3 ELISA Kits) dioxygenase was present in the very first embryo stages, in contrast to TET1 and AICDA.

  4. The GMF-Arp2 interface reveals how the ADF-H actin-binding domain in GMF is exploited to specifically recognize Arp2/3 complex and not actin.

  5. interacts with contactin and N-WASp (show WASL ELISA Kits)

  6. Data show that L. monocytogenes motility can be separated into an Arp2 (show ACTR2 ELISA Kits)/3-dependent nucleation phase, and an Arp2 (show ACTR2 ELISA Kits)/3-independent elongation phase which is dependent upon fascin (show FSCN1 ELISA Kits).

  7. crystal structures of Arp2/3 complex with bound ATP or ADP

  8. WASp stabilizes p35-dependent closure of the complex, holding Arp2 and Arp3 closer together to nucleate an actin filament.

  9. domain rearrangements of Arp2 and Arp3 result in a closed conformational state consistent with an "actin-dimer" model for the active state

  10. AICDA cDNA was cloned and expressed successfully in Escherichia coli generating a phenotype consistent with the mutating action of this deaminase. Using a whole genome radiation hybrid panel, AICDA was mapped to a region of chromosome 5.

Zebrafish Activation-Induced Cytidine Deaminase (AICDA) interaction partners

  1. there is currently no evidence to support the proposed roles of AID and MBD4 (show MBD4 ELISA Kits) in active demethylation in zebrafish embryos.

  2. Results provide evidence for a coupled mechanism of 5-methylcytosine (5-meC (show CCL28 ELISA Kits)) demethylation, whereby 5-meC (show CCL28 ELISA Kits) deaminase (AID)deaminates 5-meC (show CCL28 ELISA Kits), followed by thymine base excision by G:T mismatch-specific thymine glycosylase (Mbd4 (show MBD4 ELISA Kits)), promoted by Gadd45 (show GADD45A ELISA Kits).[AID]

  3. The promoters of both channel catfish (Ictalurus punctatus) and zebrafish (Danio rerio) Aicda genes were as transcriptionally active as an SV40 promoter control in all cell lines tested, regardless of the cells ability to express Aicda.

AICDA Antigen Profile

Antigen Summary

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).

Alternative names and synonyms associated with AICDA

  • activation-induced cytidine deaminase (AICDA) Elisa Kit
  • activation-induced cytidine deaminase (aicda) Elisa Kit
  • activation-induced cytidine deaminase (aid) Elisa Kit
  • activation-induced cytidine deaminase (Aicda) Elisa Kit
  • ARP2 actin-related protein 2 (Actr2) Elisa Kit
  • ARP2 actin-related protein 2 homolog (yeast) (ACTR2) Elisa Kit
  • 4921510D23Rik Elisa Kit
  • AA409782 Elisa Kit
  • AICDA Elisa Kit
  • Aid Elisa Kit
  • Arp2 Elisa Kit
  • CDA2 Elisa Kit
  • D6Ertd746e Elisa Kit
  • HIGM2 Elisa Kit
  • xlaid Elisa Kit

Protein level used designations for AICDA

activation-induced cytidine deaminase , activation induced deaminase , activation-induced deaminase , cytidine aminohydrolase , integrated into Burkitt's lymphoma cell line Ramos , single-stranded DNA cytosine deaminase , activation induced cytidine deaminase , aid , ARP2 actin-related protein 2 homolog , actin-like protein 2 , actin-related protein 2

GENE ID SPECIES
418257 Gallus gallus
473404 Pan troglodytes
734224 Xenopus laevis
100008969 Oryctolagus cuniculus
100304619 Ictalurus punctatus
57379 Homo sapiens
11628 Mus musculus
539888 Bos taurus
442983 Canis lupus familiaris
399679 Rattus norvegicus
493784 Danio rerio
66713 Mus musculus
538486 Bos taurus
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