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anti-Human Cathelicidin Antibodies:
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Human Polyclonal Cathelicidin Primary Antibody for IHC, ELISA - ABIN1002041
Zaiou, Gallo: Cathelicidins, essential gene-encoded mammalian antibiotics. in Journal of molecular medicine (Berlin, Germany) 2002
Show all 4 Pubmed References
Injection of CAP18 into juvenile rainbow trout before exposure to Yersinia ruckeri was associated with lowered mortality compared to non-medicated fish although it was less effective than the conventional antibiotic oxolinic acid.
Pattern recognition receptors such as TLR5 (show TLR5 Antibodies) may be involved in the stimulation of cathelicidin expression, and the signalling cascade can include PI3-kinase (show PIK3CA Antibodies) and cellular trafficking compartments.
The expression of LL-37 was up-regulated in the inflamed mucosa of IBD patients. LL-37 was induced by TLR-3 (show TLR3 Antibodies) stimulation and exhibited an anti-microbial effect via interaction with lipopolysaccharide (LPS (show IRF6 Antibodies)).
data suggest that cathelicidin LL-37 is an important element of host defense in the course of bacterial diseases within the respiratory tract, particularly when the infection is caused by an intracellular pathogen.
L-CATH-2, D-CATH-2 and LL-37 can modulate the immune response of primary chicken immune cells by increasing mannose receptor expression, antigen presentation, endocytosis and neutralizing LPS (show IRF6 Antibodies)-induced cytokine production and as a result augment activation of the adaptive immune system.
cathelicidin selectively modulated synthesis of TLR4 (show TLR4 Antibodies) and 9 in intestinal epithelium, but only when cells were exposed to virulence factors, mostly from apical surfaces.
this study shows that LL-37 may aid clearance of influenza A virus by promoting monocyte uptake of the virus, while reducing viral replication and virus-induced TNF-a (show TNF Antibodies) responses in these cells
Male placental cotyledons showed reduced basal CYP27B1 and cathelicidin gene expression compared to females.
Study demonstrates high levels of serum hBD2 (show DEFB4 Antibodies) and LL-37 levels in paediatric post- infectious bronchiolitis obliterans patients. These antimicrobial peptides may have important roles in immune systems and the pathogenesis of these patients.
the expression of CAMP, vitamin D receptor (VDR), and the retinoid X receptor (RXR) isoforms in human skin and gingival tissue biopsies and investigated the signaling pathways involved in 1alpha,25-dihydroxyvitamin D3-induced upregulation of CAMP.
A positive correlation was found between vitamin D and urine cathelicidin levels in the vitamin D sufficient group, however, there was no correlation between vitamin D and urine cathelicidin levels in the vitamin D insufficient group.
LL37 induced YB1 (show YBX1 Antibodies) expression, and increased tumor cell proliferation, migration and invasion of A375 and A875 malignant melanoma cell lines.
Cathelicidin is required for innate resistance to M. tuberculosis in a relevant animal model and is a key mediator in regulation of the levels of pro-inflammatory cytokines by calcium and cyclic nucleotides.
overexpressed CRAMP in prostate tumor initially chemoattracts early myeloid progenitors to tumor microenvironment and mediates differentiation and polarization of early myeloid progenitors into protumorigenic M2 macrophages during PCa (show ENPP1 Antibodies) progression
The aim of this project was to examine the functional impact of the human cathelicidin LL-37 and the mouse cathelicidin-related AMP (show TMPRSS5 Antibodies) (CRAMP) on the pathogenesis of lupus and arthritis.
Cathelicidin, expressed by immune cells in the tumor microenvironment, promotes colon cancer growth through activation of the PTEN (show PTEN Antibodies)/PI3K/Akt (show AKT1 Antibodies) and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathways.
pancreatic beta-cells' production is controlled by short-chain fatty acids produced by the gut (show GUSB Antibodies) microbiota, and is defective in non-obese diabetic (NOD) mice
Data indicate the role of cathelicidin-related antimicrobial peptide (CRAMP) as part of the innate immune defense against pathogens in bacterial CNS infections.
Hypoxia-inducible factor-1alpha (HIF-1alpha (show HIF1A Antibodies)), a transcription factor important for activating innate immune effectors, and the antimicrobial peptide LL-37 (CRAMP in mice) are key determinants of C. albicans colonization resistance.
Specific structural motifs in syndecan-1 (show SDC1 Antibodies) HS promote Staphylococcus aureus corneal infection by inhibiting neutrophil CRAMP.
these findings show that the production of an antimicrobial peptide Camp by adipocytes is an important element for protection against S. aureus infection of the skin
Cathelicidin-deficient (Cnlp(-/-)) mice produce much less LTB4 (show PTGR1 Antibodies) and TXB2 in vivo in response to TNF-alpha (show TNF Antibodies) compared with control mice.
Characterization of single nucleotide polymorphisms (SNPs) and insertion-deletion (indel) polymorphisms within the bovine CATHL (show CTSL1 Antibodies) gene family.
This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. The encoded protein has several functions in addition to antimicrobial activity, including cell chemotaxis, immune mediator induction and inflammatory response regulation.
cathelicidin antimicrobial peptide
, cathelicidin-derived antimicrobial peptide 2
, 18 kDa cationic antimicrobial protein
, cathelin-like protein
, cathelin-related antimicrobial peptide
, antimicrobial peptide
, antibacterial peptide BMAP-34
, cathelicidin 7
, cathelicidin 2
, myeloid antimicrobial peptide 27