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Browse our CCL5 Proteins (CCL5)

Full name:
Chemokine (C-C Motif) Ligand 5 Proteins (CCL5)
On are 122 Chemokine (C-C Motif) Ligand 5 (CCL5) Proteins from 22 different suppliers available. Additionally we are shipping CCL5 Antibodies (308) and CCL5 Kits (118) and many more products for this protein. A total of 558 CCL5 products are currently listed.
D17S136E, eoCP, MuRantes, RANTES, SCYA5, SIS-delta, SISd, TCP228
list all proteins Gene Name GeneID UniProt
CCL5 81780  
CCL5 6352 P13501
CCL5 20304 P30882

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CCL5 Proteins (CCL5) by Origin

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Top referenced CCL5 Proteins

  1. Human CCL5 Protein expressed in Escherichia coli (E. coli) - ABIN2666976 : Cocchi, DeVico, Garzino-Demo, Arya, Gallo, Lusso: Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 9 references for ABIN2666976

  2. Mouse (Murine) CCL5 Protein expressed in Escherichia coli (E. coli) - ABIN2666879 : Schall, Bacon, Toy, Goeddel: Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. in Nature 1990 (PubMed)
    Show all 6 references for ABIN2666879

  3. Human CCL5 Protein expressed in Escherichia coli (E. coli) - ABIN2666697 : Larrubia, Benito-Martínez, Calvino, Sanz-de-Villalobos, Parra-Cid: Role of chemokines and their receptors in viral persistence and liver damage during chronic hepatitis C virus infection. in World journal of gastroenterology : WJG 2008 (PubMed)
    Show all 5 references for ABIN2666697

  4. Human CCL5 Protein expressed in Human Cells - ABIN2003576 : Maghazachi, Al-Aoukaty, Schall: CC chemokines induce the generation of killer cells from CD56+ cells. in European journal of immunology 1996 (PubMed)
    Show all 5 references for ABIN2003576

  5. Human CCL5 Protein expressed in Escherichia coli (E. coli) - ABIN1046691 : Schall, Jongstra, Dyer, Jorgensen, Clayberger, Davis, Krensky: A human T cell-specific molecule is a member of a new gene family. in Journal of immunology (Baltimore, Md. : 1950) 1988 (PubMed)
    Show all 2 references for ABIN1046691

More Proteins for CCL5 Interaction Partners

Human Chemokine (C-C Motif) Ligand 5 (CCL5) interaction partners

  1. Findings show the significant upregulated expression of chemokine CCL5 (RANTES) in plasma, compared to CSF (show CSF2 Proteins) and contused brain tissue following severe traumatic brain injury (TBI (show TBPL1 Proteins)).

  2. MCP-1 (show CCL2 Proteins) and RANTES levels (ng/mg total protein) of gingivitis group were higher than those of the MSH groups (P=0.005, P=0.0001, respectively).

  3. There were no associations of CCL5 gene promoter polymorphism with the risk of diabetic microvascular complications (DMI); However, the 59029A polymorphism in CCR5 might affect individual susceptibility for DMI [Meta-Analysis]

  4. RANTES Gene Polymorphisms are Associated with HIV-1 Infections.

  5. Through the self-production of CCL5, ovarian cancer stem-like cells are induced to differentiate into endothelial cells and participate in tumor angiogenesis.

  6. monocytes and lymphocytes cooperate to enhance migration towards CXCR3 (show CXCR3 Proteins) chemokines and CCL5 in COPD (show ARCN1 Proteins)

  7. In perennial allergic rhinitis patients, we found positive correlation between RANTES levels and nasal symptom score and eosinophil counts. In patients with non-allergic rhinitis with eosinophilia syndrome, the concentrations of MCP-1 (show CCL2 Proteins) and RANTES were associated with nasal symptom score and percentage of eosinophils.

  8. Oral lipid loading is linked to reduced circulating pro-inflammatory chemokines CCL2 (show CCL2 Proteins), IP-10 (show CXCL10 Proteins), and chemerin (show RARRES2 Proteins) and to increased RANTES levels, suggesting that dietary lipids affect immune function.

  9. Results indicated that cisplatin-induced CCL5 secretion derived from the cancer-associated fibroblasts may promote cisplatin resistance, which was mediated by regulation of the STAT3 (show STAT3 Proteins) and PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) signal pathways.

  10. Authors demonstrate that the inhibition of the CCL5 expression is the cause of the observed effects resulting from RKIP (show PEBP1 Proteins) expression. Results underscore the significance of RKIP (show PEBP1 Proteins) as important negative regulator of tumor microenvironment.

Mouse (Murine) Chemokine (C-C Motif) Ligand 5 (CCL5) interaction partners

  1. Blocking antibodies against RANTES and eotaxin reduced the infiltration of CD4 (show CD4 Proteins)(+) and CD8 (show CD8A Proteins)(+) T cells into the nigra, attenuated nigral expression of proinflammatory molecules, and suppressed nigral activation of glial cells. These findings paralleled dopaminergic neuronal protection, normalized striatal neurotransmitters, and improved motor functions in MPTP (show PTPN2 Proteins)-intoxicated mice.

  2. CCL5 deficiency resulted in reduced neointima formation after carotid artery injury and thrombosis.

  3. RANTES produced by renal tubular cells act as a key chemokine (show CCL1 Proteins) in acute kidney injury and HIF-1alpha (show HIF1A Proteins) regulated LncRNA-PRINS might be involved in RANTES production.

  4. Mycobacterium chelonae activates the gene expressions of chemokine (C-C motif) ligand 2 (CCL2 (show CCL2 Proteins)) and CCL5 in murine bone marrow-derived macrophages and in vivo mouse model.

  5. Neutralization of circulating RANTES decreased liver neutrophilic infiltration

  6. CCL5 signaling through CCR5 may increase platelet counts during physiological stress.

  7. An intriguing finding was that S1P (show S1PR1 Proteins) induced c-Fos-inhibited CCL5 directly and also indirectly through inhibition of the IFN-beta (show IFNB1 Proteins) amplification loop

  8. platelet-derived CCL5 is an important link between platelet activation and neutrophil recruitment in acute colitis

  9. Nuclear FAK (show PTK2 Proteins) is associated with chromatin and exists in complex with transcription factors and their upstream regulators that control Ccl5 expression. Furthermore, FAK's immuno-modulatory nuclear activities may be specific to cancerous squamous epithelial cells, as normal keratinocytes do not have nuclear FAK (show PTK2 Proteins).

  10. that mast cells, recruited towards CCL2 and CCL5 expressed by epithelium induced to proliferate by Human Papillomavirus 16 E7 protein

Pig (Porcine) Chemokine (C-C Motif) Ligand 5 (CCL5) interaction partners

  1. These results represent an important molecular mechanism whereby H. parasuis induced RANTES in the inflammatory response.

  2. Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced RANTES transcription.

  3. we cloned the nucleotide sequence of the 5'-flanking region of the porcine RANTES (poRANTES) gene and characterized the regulatory elements that activate transcription

  4. The Toll (show TLR4 Proteins)-like receptor signaling pathway is involved in porcine reproductive and respiratory syndrome virus-induced RANTES activation.

  5. These results suggest that porcine RANTES can play an important role in xenotransplant rejection, through participating in the interaction between porcine endothelial cells and human monocytes.

Cow (Bovine) Chemokine (C-C Motif) Ligand 5 (CCL5) interaction partners

  1. CCL5 but not CCL2 (show CCL2 Proteins) mainly attract bovine classical monocytes and promote their differentiation into LPS (show IRF6 Proteins)-hypo-responsive macrophages.

  2. decrease in sensitivity of HIV variants to RANTES neutralization during the course of progressive infection, but not during follow-up of long term survivors; data suggest a role for RANTES neutralization sensitivity of HIV-1 in AIDS pathogenesis

Guinea Pig Chemokine (C-C Motif) Ligand 5 (CCL5) interaction partners

  1. In the pathogenesis of allergic rhinitis, substance P (show TAC1 Proteins) induces expression of RANTES in nasal mucosa.

Rhesus Monkey Chemokine (C-C Motif) Ligand 5 (CCL5) interaction partners

  1. CCL3 (show CCL3 Proteins), CCL4 (show CCL4 Proteins) and CCL5 gene expression was evaluated in response to simian-human immunodeficiency virus (SHIV) infection in a rhesus macaque model.

CCL5 Protein Profile

Protein Summary

This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.

Alternative names and synonyms associated with CCL5

  • chemokine (C-C motif) ligand 5 (LOC100230935)
  • chemokine (C-C motif) ligand 5 (CCL5)
  • chemokine (C-C motif) ligand 5 (Ccl5)
  • D17S136E protein
  • eoCP protein
  • MuRantes protein
  • RANTES protein
  • SCYA5 protein
  • SIS-delta protein
  • SISd protein
  • TCP228 protein

Protein level used designations for CCL5

chemokine (C-C motif) ligand 5 , small inducible cytokine A5 , C-C motif chemokine 5 , SIS-delta , T-cell-specific protein RANTES , regulated upon activation normal T-cell expressed and secreted , small-inducible cytokine A5 , T-cell specific protein p288 , beta-chemokine RANTES , eosinophil chemotactic cytokine , regulated upon activation, normally T-expressed, and presumably secreted , small inducible cytokine subfamily A (Cys-Cys), member 5 , chemokine ah294 , small inducible cytokine A5 RANTES , chemokine CCL5/RANTES , chemokine ligand 5

100230935 Taeniopygia guttata
747004 Pan troglodytes
81780 Rattus norvegicus
6352 Homo sapiens
20304 Mus musculus
417465 Gallus gallus
403522 Canis lupus familiaris
396613 Sus scrofa
327712 Bos taurus
100135495 Cavia porcellus
493689 Felis catus
100033925 Equus caballus
101115553 Ovis aries
574178 Macaca mulatta
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