Browse our IL-10 Proteins (IL10)

Full name:
Interleukin 10 Proteins (IL10)
On www.antibodies-online.com are 180 Interleukin 10 (IL10) Proteins from 23 different suppliers available. Additionally we are shipping IL-10 Antibodies (683) and IL-10 Kits (305) and many more products for this protein. A total of 1193 IL-10 products are currently listed.
Synonyms:
CSIF, GVHDS, Il-10, IL10A, IL10X, TGIF
list all proteins Gene Name GeneID UniProt
IL10 3586 P22301
IL10 16153 P18893
Rat IL10 IL10 25325 P29456

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IL-10 Proteins (IL10) by Origin

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Top referenced IL-10 Proteins

  1. Human IL-10 Protein expressed in Escherichia coli (E. coli) - ABIN2666701 : Asadullah, Sterry, Volk: Interleukin-10 therapy--review of a new approach. in Pharmacological reviews 2003 (PubMed)
    Show all 6 references for 2666701

  2. Mouse (Murine) IL-10 Protein expressed in Escherichia coli (E. coli) - ABIN1305073 : Howard, OGarra, Ishida, de Waal Malefyt, de Vries: Biological properties of interleukin 10. in Journal of clinical immunology 1992 (PubMed)
    Show all 4 references for 1305073

  3. Cat (Feline) IL-10 Protein expressed in Escherichia coli (E. coli) - ABIN2008820 : Yoon, Jones, Logsdon, Walter: Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain. in Structure (London, England : 1993) 2005 (PubMed)
    Show all 3 references for 2008820

  4. Human IL-10 Protein expressed in Escherichia coli (E. coli) - ABIN413418 : van der Vliet, Wang, Yue, Koon, Balk, Exley: Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 3 references for 413418

  5. Human IL-10 Protein expressed in Escherichia coli (E. coli) - ABIN2003641 : Gesser, Leffers, Jinquan, Vestergaard, Kirstein, Sindet-Pedersen, Jensen, Thestrup-Pedersen, Larsen: Identification of functional domains on human interleukin 10. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 2 references for 2003641

  6. Human IL-10 Protein expressed in Escherichia coli (E. coli) - ABIN1305072 : Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 2 references for 1305072

  7. Rat (Rattus) IL-10 Protein expressed in Escherichia coli (E. coli) - ABIN2009133 : Cui, Feng, Wang, Zhao: [Expression of RhoA in the lung tissue of acute lung injury rats and the influence of RhoA on the expression of IL-8 and IL-10]. in Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 2011 (PubMed)

More Proteins for IL-10 Interaction Partners

Human Interleukin 10 (IL10) interaction partners

  1. The results of this study showed lack of association with schizophrenia was detected for IL10 and IL10RA (show IL10RA Proteins) single polymorphisms and haplotypes.

  2. modulation of the expression of VDR (show CYP27B1 Proteins) can regulate the expression of IL-10 in peripheral B cells of pituitary gland tumour (PGT (show SLCO2A1 Proteins))patients, which may contribute to the treatment of PGT (show SLCO2A1 Proteins).

  3. IL-10 592A/C and 819T/C promoter polymorphisms confer susceptibility to advanced endometriosis. No associations were found between the IL-10 1082A/G polymorphism and susceptibility to advanced endometriosis.

  4. Some IL10 tagSNPs were associated with lower- and higher-grade Prostate cancer.

  5. Interleukin-10-1082 G/A and Tumor Necrosis Factor-alpha (show TNF Proteins) 308 G/A gene polymorphisms may be associated with respiratory distress syndrome in Iranian preterm infants

  6. in HIV/AIDS patients under antiretroviral therapy, IL-4 (show IL4 Proteins) and IL-10 levels were significantly lower in lipodystrophy vs. non-lipodystrophy

  7. hepatitis C virus infected patients carrying low production haplotypes of IL-10 and the TNF-alpha (show TNF Proteins) GG genotype have higher risk to develop hepatocellular carcinoma

  8. genotype GG and GT of IL-10 (rs1800872) were associated with increased risk of infection with influenza A/H3N2 virus

  9. EPO (show EPO Proteins) levels were also found correlated positively with heme, TNF-alpha (show TNF Proteins), IL-10, IP-10 (show CXCL10 Proteins) and MCP-1 (show CCL2 Proteins) during cerebral malaria.

  10. this study shows that active cow's milk-induced enterocolitis syndrome children have lower baseline serum levels of IL-10 compared to resolved disease

Mouse (Murine) Interleukin 10 (IL10) interaction partners

  1. These results demonstrate the importance of skeletal muscle inflammation in aging-mediated insulin (show INS Proteins) resistance, and our findings further implicate a potential therapeutic role of anti-inflammatory cytokine in the treatment of aging-mediated insulin (show INS Proteins) resistance.

  2. resistance to antibody-mediated Transfusion-related acute lung injury was associated with increased interleukin-10 (IL-10) levels, and IL-10 levels were found to be decreased in mice suffering from Transfusion-related acute lung injury. Importantly, IL-10 injection completely prevented and rescued the development of Transfusion-related acute lung injury in mice

  3. IL-10 expression is significantly increased following a specific deletion of DNGR-1 (show CLEC9A Proteins) in vascular inflammation and atherosclerosis.

  4. inhibition of transcription is the primary mechanism for IL-10-mediated suppression of inflammatory gene expression following microbial stimuli

  5. Tregs ameliorated ICH-induced inflammatory injury by modulating microglia/macrophage polarization toward the M2 phenotype through the IL-10/GSK3beta/PTEN axis

  6. this studies provide information on how IL-10 may contribute to optimized parasite control and prevention of immune-mediated pathology during repeated malaria infections

  7. this study shows that IL-4 (show IL4 Proteins) and IL-10 are important for the altered peptide ligand-induced attenuation of experimental arthritis

  8. These results demonstrate that HIF-1alpha (show HIF1A Proteins) is critical for controlling the progression of infection with the fungal pathogen H. capsulatum by limiting IL-10.

  9. we report that IL-10 is essential for anti-Plasmodium humoral immunity

  10. IL-33 (show IL33 Proteins) receptor-expressing regulatory T cells are highly activated, Th2 biased and suppress CD4 (show CD4 Proteins) T cell proliferation through IL-10 and TGFbeta (show TGFB1 Proteins) release.

Cow (Bovine) Interleukin 10 (IL10) interaction partners

  1. This study seems to indicate that PGE2 in cattle does not produce an anti-inflammatory effect by increasing the synthesis of IL-10.

  2. IL-10 mRNA expression increased on day 8 in the mononuclear leukocytes of pregnant cows. In a cell culture experiment, interferon-tau stimulated stimulated IL-10 mRNA expression in mononuclear leukocytes.

  3. Bovine IL-10 potently inhibits the activation of human myeloid cells in response to toll (show TLR4 Proteins) like receptor activation.

  4. Monocytes obtained from cows with subclinical infection with MAP had upregulated expression of IL-10 and SOCS-3 (show SOCS3 Proteins), which may have attenuated the capacity of mononuclear phagocytes to initiate inflammatory and adaptive immune responses.

Horse (Equine) Interleukin 10 (IL10) interaction partners

  1. The ability of an EHV-1 isolate to down-regulate IL-10 production might contribute to increased local inflammation and a higher risk for neurological manifestation of the disease after infection with Ab4.

  2. The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Proteins) biased, interferon-gamma (show IFNG Proteins) production is qualitatively similar to adult horses, and regulatory IL-10 production by T cells is mature.

  3. serum IL-6 (show IL6 Proteins):IL-10 ratio is likely to provide a valuable prognosticator for neonatal septicemia

  4. The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6 (show IL6 Proteins), IL-10 and TNF-alpha (show TNF Proteins), in horses with recurrent airway obstruction during exacerbation and in remission is reported.

Guinea Pig Interleukin 10 (IL10) interaction partners

  1. The complete open reading frame consists of 537 base pairs which encodes a protein of 179 amino acids. This cDNA sequence exhibited 87% homology with human IL-10.

Rabbit Interleukin 10 (IL10) interaction partners

  1. ICAM1 (show ICAM1 Proteins) and IL10 were upregulated in ventilator-induced lung injury. Nuclear transcription factor AP-1 (show JUN Proteins) may be responsible for this upregulation.

Pig (Porcine) Interleukin 10 (IL10) interaction partners

  1. The PRRSV vaccination induced higher levels of IL-10 expression in the first week and this may be why the CSFV vaccination is immunosuppressed.

  2. These data indicate that the type 2 porcine reproductive and respiratory syndrome virus N protein plays an important role in IL-10 induction and the N-N non-covalent domain is associated with this activity.

  3. The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (show TGFB1 Proteins), IL-10, and IL-6 (show IL6 Proteins) in ovarian follicles are reported.

  4. Prostaglandin E2 potentiates mesenchymal stem cell-induced IL-10+IFN-gamma (show IFNG Proteins)+CD4 (show CD4 Proteins)+ regulatory T cells to control transplant arteriosclerosis.

  5. Porcine reproductive and respiratory syndrome virus strain CH-1a could significantly up-regulate IL-10 production through p38 MAPK (show MAPK14 Proteins) activation.

  6. Boar seminal plasma contained TGF- beta1 (show TGFB1 Proteins) and IL-10 but with high individual variation.

  7. Changes in interleukin-10 mRNA expression are predictive for 9-day survival of pigs in an emergency preservation and resuscitation model.

  8. These results suggest that TNF-alpha (show TNF Proteins) and IL-10, but not IL-6 (show IL6 Proteins), are involved in the late reparatory phases of the experimental disk lesion.

  9. The present study shows that elevated levels of serum CRP (show CRP Proteins) and IL-10 were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS.(postweaning multisystemic wasting syndrome)

  10. Subclinically porcine circovirus type 2 (PCV2)-infected pigs developed a transient PCV2-specific IL-10 response during the viremic phase of infection which coincided with the inversion of the IgM/IgG ratio.

Rhesus Monkey Interleukin 10 (IL10) interaction partners

  1. IL-10 produced during the immune response to malaria in this model contributes to suppression of mucosal inflammatory responses to invasive NTS (show NTS Proteins), which may contribute to differences in the clinical presentation of NTS (show NTS Proteins) infection in the setting of malaria.

  2. Findings demonstrate that internalization of IL-10R with the resultant impact on IL-10 signaling and dysregulation of the IL-10-mediated anti-inflammatory responses might play a crucial role in epithelial cell damage and subsequent simian immunodeficiency virus pathogenesis.

  3. IL-10 plays a crucial role in maintaining mucosal homeostasis by regulating mucosal IFNgamma and TNFalpha (show TNF Proteins) cytokine production.

IL-10 (IL10) Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Alternative names and synonyms associated with IL-10 (IL10)

  • interleukin 10 (IL10)
  • interleukin 10 (Il10)
  • CSIF protein
  • GVHDS protein
  • Il-10 protein
  • IL10A protein
  • IL10X protein
  • TGIF protein

Protein level used designations for Interleukin 10 Proteins (IL10)

T-cell growth inhibitory factor , cytokine synthesis inhibitory factor , interleukin-10 , CSIF , IL-10 , uncharacterized protein LOC100715618 , Cytokine synthesis inhibitory factor , Interleukin-10

GENE ID SPECIES
3586 Homo sapiens
16153 Mus musculus
25325 Rattus norvegicus
281246 Bos taurus
100034187 Equus caballus
443342 Ovis aries
403628 Canis lupus familiaris
428264 Gallus gallus
100860746 Capra hircus
100715618 Cavia porcellus
100008701 Oryctolagus cuniculus
397106 Sus scrofa
493683 Felis catus
694931 Macaca mulatta
100386149 Callithrix jacchus
469657 Pan troglodytes
101271889 Orcinus orca
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