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Browse our anti-Metadherin (MTDH) Antibodies

Full name:
anti-Metadherin Antibodies (MTDH)
On www.antibodies-online.com are 98 Metadherin (MTDH) Antibodies from 21 different suppliers available. Additionally we are shipping Metadherin Kits (9) and Metadherin Proteins (8) and many more products for this protein. A total of 120 Metadherin products are currently listed.
Synonyms:
3D3, 3D3/Lyric, 2610103J23Rik, AEG-1, AEG1, AV353288, D8Bwg1112e, LYRIC, LYRIC/3D3, MGC75963

Most Popular Reactivities for anti-Metadherin (MTDH) Antibodies

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anti-Mouse (Murine) Antibodies:

anti-Rat (Rattus) Antibodies:

anti-Human Antibodies:

All available anti-Metadherin Antibodies

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Top referenced anti-Metadherin Antibodies

  1. Human Polyclonal MTDH Primary Antibody for IF (p), IHC (p) - ABIN678863 : Guo, Zhang, Liu, Wang, Liu, Wang, Ma, Wu: Astrocyte elevated gene-1 overexpression in histologically favorable Wilms tumor is related to poor prognosis. in Journal of pediatric urology 2014 (PubMed)
    Show all 4 references for ABIN678863

  2. Human Monoclonal MTDH Primary Antibody for FACS, IHC - ABIN969496 : Britt, Yang, Yang, Flanagan, Callanan, Lim, Lin, Hixson: Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells. in Experimental cell research 2004 (PubMed)
    Show all 2 references for ABIN969496

  3. Human Monoclonal MTDH Primary Antibody for ELISA, FACS - ABIN4332034 : Wang, Lim, Shi, Lee, Deng, Xie, Zhu, Wang, Pocalyko, Yang, Rejto, Mao, Park, Xu: Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma. in Hepatology (Baltimore, Md.) 2013 (PubMed)
    Show all 2 references for ABIN4332034

  4. Human Polyclonal MTDH Primary Antibody for ICC, IF - ABIN4332035 : Nohata, Hanazawa, Kikkawa, Mutallip, Sakurai, Fujimura, Kawakami, Chiyomaru, Yoshino, Enokida, Nakagawa, Okamoto, Seki: Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC). in Journal of human genetics 2011 (PubMed)
    Show all 2 references for ABIN4332035

  5. Human Polyclonal MTDH Primary Antibody for ICC, IF - ABIN4332036 : Liu, Wu, Peng: Astrocyte elevated gene-1 regulates osteosarcoma cell invasion and chemoresistance via endothelin-1/endothelin A receptor signaling. in Oncology letters 2013 (PubMed)

More Antibodies against Metadherin Interaction Partners

Mouse (Murine) Metadherin (MTDH) interaction partners

  1. AEG-1 thus might play a role in NTIS associated with HCC (show FAM126A Antibodies) and other cancers.

  2. When fed a high fat and cholesterol diet (HFD), WT mice rapidly gained weight, whereas AEG-1 KO mice did not gain weight at all.

  3. MTDH has a critical role in male fertility and the DNA repair mechanisms required for normal spermatogenesis

  4. Data provide evidence that MTDH has a functional role in the progression and metastatic spread of ovarian cancer.

  5. RNA-sequencing analysis identified a unique gene signature in livers of Alb (show ALB Antibodies)/AEG-1/c-Myc (show MYC Antibodies) mice that was not observed when either AEG-1 or c-Myc (show MYC Antibodies) was overexpressed

  6. Findings establish a pivotal role for MTDH in prostate cancer progression and metastasis.

  7. IL-1beta (show IL1B Antibodies)- or TNF-alpha (show TNF Antibodies)-induced AEG-1 interaction with NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies) subunit.

  8. MTDH supports the survival of mammary epithelial cells under oncogenic/stress conditions by interacting with and stabilizing SND1 (show SND1 Antibodies).

  9. oncogene (show RAB1A Antibodies) metadherin modulates the apoptotic pathway based on the tumor necrosis factor (show TNF Antibodies) superfamily member TRAIL (Tumor Necrosis Factor (show TNF Antibodies)-related Apoptosis-inducing Ligand) in breast cancer

  10. The present findings report the novel role of AEG-1 in mediating reactive astrogliosis and in regulating astrocyte responses to injury.

Human Metadherin (MTDH) interaction partners

  1. our findings suggest that AEG-1 promotes mesenchymal transition in glioblastoma through the regulation of the Rho signaling pathway, resulting in tumor invasion, a primary characteristic of malignant brain tumors

  2. these findings suggested that miR (show MLXIP Antibodies)-124 was able to suppress cell proliferation, invasion and migration, as well as the EMT (show ITK Antibodies) process in cervical carcinomas through directly targeting AEG-1. miR (show MLXIP Antibodies)-124 and AEG-1 may be potential

  3. Our results suggest that underexpression of miR (show MLXIP Antibodies)-30a-5p might function as a tumor suppressing miRNA by directly targeting MTDH in HCC (show FAM126A Antibodies) and is therefore a potential candidate biomarker for HCC (show FAM126A Antibodies) targeting therapy.

  4. MiR (show MLXIP Antibodies)-136 plays a key role in temozolomide (TMZ) resistance by targeting AEG-1 in glioma cell line, suggesting that miR (show MLXIP Antibodies)-136 can be used to predict a patient's response to TMZ therapy as well as serve as a novel potential maker for glioma therapy.

  5. Data indicate metadherin (MTDH) as a direct target gene of microRNA miR (show MLXIP Antibodies)-630.

  6. AEG-1 overexpression is closely associated with epithelial-mesenchymal transition and promote metastasis in tongue squamous cell carcinoma.

  7. MiR (show MLXIP Antibodies)-30a-5p may play an essential role in the cell growth and apoptosis of hepatocellular carcinoma cells, partially via targeting AEG-1.

  8. Suggest that miR (show MLXIP Antibodies)-377 plays an important role in the development of NSCLC by regulating AEG-1 expression.

  9. High MTDH expression is associated with multiple myeloma.

  10. In patients with non-small cell lung cancer, AEG-1 expression was an independent prognostic factor for both overall and disease-free survival.

Metadherin (MTDH) Antigen Profile

Antigen Summary

human and mouse homologs are overexpressed in breast cancer tissue, bind to lung vasculature, and may play a role in promoting metastasis

Alternative names and synonyms associated with Metadherin (MTDH)

  • metadherin (mtdh) antibody
  • metadherin (MTDH) antibody
  • metadherin (Mtdh) antibody
  • 3D3 antibody
  • 3D3/Lyric antibody
  • 2610103J23Rik antibody
  • AEG-1 antibody
  • AEG1 antibody
  • AV353288 antibody
  • D8Bwg1112e antibody
  • LYRIC antibody
  • LYRIC/3D3 antibody
  • MGC75963 antibody

Protein level used designations for anti-Metadherin (MTDH) Antibodies

metadherin , LYRIC/3D3 , protein LYRIC , protein LYRIC-like , lysine-rich CEACAM1 co-isolated protein , metastasis adhesion protein , LYRIC , 3D3/LYRIC , astrocyte elevated gene-1 protein

GENE ID SPECIES
394771 Xenopus (Silurana) tropicalis
420239 Gallus gallus
472825 Pan troglodytes
509788 Bos taurus
612147 Canis lupus familiaris
702410 Macaca mulatta
100059885 Equus caballus
100153168 Sus scrofa
100385408 Callithrix jacchus
100444491 Pongo abelii
100579266 Nomascus leucogenys
67154 Mus musculus
170910 Rattus norvegicus
92140 Homo sapiens
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