Browse our anti-PAF1 (PAF1) Antibodies

Full name:
anti-Paf1, RNA Polymerase II Associated Factor, Homolog (S. Cerevisiae) Antibodies (PAF1)
On www.antibodies-online.com are 60 Paf1, RNA Polymerase II Associated Factor, Homolog (S. Cerevisiae) (PAF1) Antibodies from 14 different suppliers available. Additionally we are shipping PAF1 Proteins (3) and many more products for this protein. A total of 65 PAF1 products are currently listed.
Synonyms:
5730511K23Rik, AA675045, F23149_1, im:6906070, paf1, paf1l, PD2, RGD1306219, wu:fb80a09

Most Popular Reactivities for anti-PAF1 (PAF1) Antibodies

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anti-Human PAF1 Antibodies:

anti-Mouse (Murine) PAF1 Antibodies:

anti-Rat (Rattus) PAF1 Antibodies:

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Top referenced anti-PAF1 Antibodies

  1. Human Polyclonal PAF1 Primary Antibody for WB - ABIN153212 : Lin, Czapiga, Nini, Zhang, Simonds: Nuclear localization of the parafibromin tumor suppressor protein implicated in the hyperparathyroidism-jaw tumor syndrome enhances its proapoptotic function. in Molecular cancer research : MCR 2007 (PubMed)
    Show all 5 references for 153212

  2. Human Polyclonal PAF1 Primary Antibody for ICC, IF - ABIN153213 : Chipumuro, Henriksen: The ubiquitin hydrolase USP22 contributes to 3'-end processing of JAK-STAT-inducible genes. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 (PubMed)

More Antibodies against PAF1 Interaction Partners

Human Paf1, RNA Polymerase II Associated Factor, Homolog (S. Cerevisiae) (PAF1) interaction partners

  1. High PAF1 (show PEX2 Antibodies) expression is associated with ovarian cancer.

  2. Overexpression of PD2 leads to increased tumorigenicity and metastasis in pancreatic ductal adenocarcinoma.

  3. Propose that degradation of MYC (show MYC Antibodies) limits the accumulation of MYC (show MYC Antibodies)/PAF1C complexes during transcriptional activation.

  4. Mechanistic studies indicated that PAF1C could promote lung cancer cell proliferation through regulating c-MYC (show MYC Antibodies) transcription.

  5. CNOT4 (show CNOT4 Antibodies) controls the degradation of chromatin-unbound PAF1 (show PEX2 Antibodies) via the 26S proteasome (show Psmd4 Antibodies).

  6. this study found that Pol II-associated factor 1 (PAF1 (show PEX2 Antibodies)) is a critical regulator of paused Pol II release, that positive transcription elongation factor b (P-TEFb (show CDK9 Antibodies)) directly regulates the initial recruitment of PAF1 (show PEX2 Antibodies) complex (PAF1C) to genes, and that the subsequent recruitment of CDK12 (show CRKRS Antibodies) is dependent on PAF1C.

  7. This study reveals an evolutionarily conserved role for PAF1 (show PEX2 Antibodies) as a regulator of promoter-proximal pausing by RNA Pol II in all metazoans, including human.

  8. PD2 is a novel cancer stem cell (CSC) maintenance protein, loss of which renders the CSCs more susceptible to drug-induced cell death.

  9. Together, these results indicate that human adenovirus E1A (show BCKDHA Antibodies) uses hBre1 (show RNF20 Antibodies) to recruit the hPaf1 complex in order to optimally activate viral early transcription by enhancing transcriptional elongation.

  10. The results show that the Paf1 (show PEX2 Antibodies)/Leo1 (show LEO1 Antibodies) heterodimer is necessary for its binding to histone H3 (show HIST3H3 Antibodies), the histone octamer, and nucleosome in vitro.

Mouse (Murine) Paf1, RNA Polymerase II Associated Factor, Homolog (S. Cerevisiae) (PAF1) interaction partners

  1. link Paf1C with PolII elongation and RNA processing indicates that Paf1C subunits could play roles in controlling transcript length through suppression of PolII accumulation at transcription start site (TSS (show RPL38 Antibodies))-proximal pA sites

  2. The PAF1 (show PEX2 Antibodies) complex is required for mammalian development, likely through regulation of H3K36me3, indicating a functional conservation of the PAF1 (show PEX2 Antibodies) complex from yeast to mammals in vivo.

  3. As part of a cell-intrinsic transcriptional pathway, Paf1 (show PEX2 Antibodies) regulates neuronal migration in the brain.

  4. MLL (show MLL Antibodies) interacts directly with the polymerase associated factor complex (PAFc) via Paf1 (show PEX2 Antibodies) and CTR9 (show CTR9 Antibodies). PAFc augments MLL (show MLL Antibodies) and MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies) mediated transcriptional activation of Hoxa9 (show HOXA9 Antibodies) and their interaction is essential for leukemogenesis.

  5. show that Paf1/PD2 is overexpressed in mouse embryonic stem cells (ESCs (show NR2E3 Antibodies)) and is involved in the maintenance of mouse ESCs (show NR2E3 Antibodies).

Zebrafish Paf1, RNA Polymerase II Associated Factor, Homolog (S. Cerevisiae) (PAF1) interaction partners

  1. The PAF1 complex differentially regulates cardiomyocyte specification.

PAF1 Antigen Profile

Antigen Summary

This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with PAF1

  • Paf1, RNA polymerase II associated factor, homolog (paf1) antibody
  • RNA polymerase II-associated factor 1 homolog (LOC100019208) antibody
  • RNA polymerase II-associated factor 1 homolog (LOC100161171) antibody
  • Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) (PAF1) antibody
  • RNA polymerase II-associated factor 1 homolog (paf1) antibody
  • RNA polymerase II-associated factor 1 homolog (LOC100411768) antibody
  • RNA polymerase II-associated factor 1 homolog (LOC100465029) antibody
  • RNA polymerase II-associated factor 1 homolog (LOC100543667) antibody
  • RNA polymerase II-associated factor 1 homolog (LOC100594485) antibody
  • RNA polymerase II-associated factor 1 homolog (LOC100625528) antibody
  • RNA polymerase II-associated factor 1 homolog (LOC100639019) antibody
  • RNA polymerase II-associated factor 1 homolog (LOC100650306) antibody
  • Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) (Paf1) antibody
  • paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) (paf1) antibody
  • 5730511K23Rik antibody
  • AA675045 antibody
  • F23149_1 antibody
  • im:6906070 antibody
  • paf1 antibody
  • paf1l antibody
  • PD2 antibody
  • RGD1306219 antibody
  • wu:fb80a09 antibody

Protein level used designations for PAF1

RNA polymerase II-associated factor 1 homolog , pancreatic differentiation protein 2 , PD2-like protein , paf1, RNA polymerase II associated factor, homolog, like

GENE ID SPECIES
394974 Xenopus (Silurana) tropicalis
100019208 Monodelphis domestica
100161171 Acyrthosiphon pisum
100172552 Pongo abelii
100194999 Salmo salar
100411768 Callithrix jacchus
100465029 Ailuropoda melanoleuca
100514194 Sus scrofa
100543667 Meleagris gallopavo
100594485 Nomascus leucogenys
100625528 Sus scrofa
100639019 Amphimedon queenslandica
100650306 Bombus terrestris
446278 Xenopus laevis
54623 Homo sapiens
54624 Mus musculus
361531 Rattus norvegicus
528744 Bos taurus
553020 Danio rerio
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