Browse our anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) Antibodies

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anti-phosphodiesterase 4B, cAMP-Specific Antibodies (PDE4B)
On are 99 phosphodiesterase 4B, cAMP-Specific (PDE4B) Antibodies from 17 different suppliers available. Additionally we are shipping phosphodiesterase 4B, cAMP-Specific Kits (11) and phosphodiesterase 4B, cAMP-Specific Proteins (8) and many more products for this protein. A total of 128 phosphodiesterase 4B, cAMP-Specific products are currently listed.
DPDE4, dunce, PDE4/IVb, Pde4B1, Pde4B2, Pde4B3, Pde4B4, PDE4B5, PDEIVB, R74983
list all antibodies Gene Name GeneID UniProt
PDE4B 18578  
PDE4B 24626 P14646
PDE4B 5142 Q07343

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Top referenced anti-phosphodiesterase 4B, cAMP-Specific Antibodies

  1. Cow (Bovine) Polyclonal PDE4B Primary Antibody for WB - ABIN2786603 : Fatemi, King, Reutiman, Folsom, Laurence, Lee, Fan, Paciga, Conti, Menniti: PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia. in Schizophrenia research 2008 (PubMed)
    Show all 2 references for 2786603

  2. Human Polyclonal PDE4B Primary Antibody for EIA, FACS - ABIN954065 : Souza, Remington, Meltzer, Lieberman, Kennedy, Wong: Phosphodiesterase 4B genetic variants are not associated with antipsychotic-induced tardive dyskinesia. in International clinical psychopharmacology 2010 (PubMed)
    Show all 2 references for 954065

  3. Mouse (Murine) Polyclonal PDE4B Primary Antibody for ELISA, WB - ABIN250999 : Millar, Pickard, Mackie, James, Christie, Buchanan, Malloy, Chubb, Huston, Baillie, Thomson, Hill, Brandon, Rain, Camargo, Whiting, Houslay, Blackwood, Muir, Porteous: DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. in Science (New York, N.Y.) 2005 (PubMed)

  4. Human Polyclonal PDE4B Primary Antibody for ICC, IF - ABIN4344430 : Cedervall, Aulabaugh, Geoghegan, McLellan, Pandit: Engineered stabilization and structural analysis of the autoinhibited conformation of PDE4. in Proceedings of the National Academy of Sciences of the United States of America 2015 (PubMed)

  5. Chicken Polyclonal PDE4B Primary Antibody for WB - ABIN493273 : Huston, Lumb, Russell, Catterall, Ross, Steele, Bolger, Perry, Owens, Houslay: Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3. in The Biochemical journal 1998 (PubMed)

More Antibodies against phosphodiesterase 4B, cAMP-Specific Interaction Partners

Mouse (Murine) phosphodiesterase 4B, cAMP-Specific (PDE4B) interaction partners

  1. These results demonstrate that the alcohol- induced increase in hepatic Pde4 (show PDE4A Antibodies), specifically Pde4b expression, and compromised cAMP signalling predispose the liver to impaired fatty acid oxidation and the development of steatosis.

  2. PDE4B phosphorylated by AMPK (show PRKAA1 Antibodies) at Ser304 is important for activation.

  3. Lymphomas developing in a Pde4b-null background display significantly lower microvessel density in association with lower VEGF (show VEGFA Antibodies) levels and PI3K/AKT (show AKT1 Antibodies) activity.

  4. Genetic variations in DISC1 (show DISC1 Antibodies) influence formation of biochemical complex with PDE4 (show PDE4A Antibodies) and GSK-3 (show GSK3b Antibodies) and strengthen the possibility of synergistic interactions between these proteins.

  5. PDE4B-deficient mice display impaired reversal learning in the Morris water maze compared to wild-type littermates.

  6. Results identify PDE4B in the CaV1.2 (show CACNA1C Antibodies) complex as a critical regulator of ICa during beta-AR stimulation and suggest that distinct PDE4 (show PDE4A Antibodies) subtypes are important for normal regulation of calcium-induced calcium release in cardiomyocytes.

  7. Findings demonstrate that PDE4D (show PDE4D Antibodies) and PDE4B have specialized functions in mouse embryonic fibroblasts with PDE4B controlling cAMP in a discrete subdomain near the plasma membrane.

  8. induction is esssential for LPS (show TLR4 Antibodies)-activated tnf-alpha (show TNF Antibodies) responses

  9. PDE4B mediates the antipsychotic effects of rolipram in conditioned avoidance responding; the PDE4B-regulated cyclic adenosine monophosphate signaling pathway may play a role in the pathophysiology and pharmacotherapy of psychosis

  10. the PDE4B subfamily is involved in signaling pathways that contribute to anxiogenic-like effects on behavior.

Human phosphodiesterase 4B, cAMP-Specific (PDE4B) interaction partners

  1. HTT (show HTT Antibodies) forms a ternary protein complex with the scaffolding protein DISC1 (show DISC1 Antibodies) and cAMP-degrading phosphodiesterase 4 (PDE4 (show PDE4A Antibodies)) to regulate PDE4 (show PDE4A Antibodies) activity.

  2. Low PDE4B expression is associated with sepsis.

  3. PDE4B gene may be involved in the testicular abnormalities of men with DS and cryptorchidism.

  4. This meta-analysis suggests that PDE4B SNPs are genetically associated with susceptibility to schizophrenia.

  5. Our results suggest that PDE4B does not play an important role during the chemotactic response of human neutrophils

  6. Our results support previously reported association of PDE4B variations with schizophrenia in other populations.

  7. analysis of the mechanism underlying synergistic up-regulation of PDE4B2 via a cross-talk between PKA-Cbeta and p65 (show GORASP1 Antibodies)

  8. ototopical post-inoculation administration of a PDE4 (show PDE4A Antibodies) inhibitor suppresses inflammation in this animal model, thus demonstrating the therapeutic potential of targeting PDE4 (show PDE4A Antibodies)

  9. PDE4B was found to be highly expressed in CD4 (show CD4 Antibodies)+ lymphoid cancer cells, which suggests that it may represent a physiological role unique to the CD8 (show CD8A Antibodies)+ and lymphoid cancer cells and thus might represent a target for treatment of certain lymphoid diseases

  10. Short Disrupted-in-Schizophrenia (DISC)1 (show DISC1 Antibodies) splice variants show reduced or no binding to nudE nuclear distribution E homolog (NDEL)1 (show NDEL1 Antibodies) and PDE4B proteins but fully interact with fasciculation/elongation zeta (FEZ)1 (show LZTS1 Antibodies) and glycogen synthase kinase 3 GSK3beta (show GSK3b Antibodies).

Pig (Porcine) phosphodiesterase 4B, cAMP-Specific (PDE4B) interaction partners

  1. QTL-CI for IMF (show MDFI Antibodies) was reconfirmed with high significance, and its position was narrowed down to an interval of 4 cM (the region defined by markers PDE4B and SW1881)

phosphodiesterase 4B, cAMP-Specific (PDE4B) Antigen Profile

Antigen Summary

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with phosphodiesterase 4B, cAMP-Specific (PDE4B)

  • phosphodiesterase 4B, cAMP-specific (pde4b) antibody
  • phosphodiesterase 4B, cAMP-specific (PDE4B) antibody
  • phosphodiesterase 4B, cAMP specific (Pde4b) antibody
  • DPDE4 antibody
  • dunce antibody
  • PDE4/IVb antibody
  • Pde4B1 antibody
  • Pde4B2 antibody
  • Pde4B3 antibody
  • Pde4B4 antibody
  • PDE4B5 antibody
  • PDEIVB antibody
  • R74983 antibody

Protein level used designations for PDE4B

phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog) , phosphodiesterase 4B, cAMP-specific , phosphodiesterase 4B , 3',5'-cyclic AMP phosphodiesterase , DPDE4 , Phosphodiesterase 4B cAMP-specific (dunce , Phosphodiesterase 4B, cAMP-specific (dunce , cAMP-specific 3',5'-cyclic phosphodiesterase 4B , PDE32 , cAMP-specific phosphodiesterase-4 B isoform , dunce-like phosphodiesterase E4 , phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) , phosphodiesterase 4B, cAMP specific

780324 Xenopus (Silurana) tropicalis
100604983 Nomascus leucogenys
18578 Mus musculus
24626 Rattus norvegicus
5142 Homo sapiens
424700 Gallus gallus
444562 Xenopus laevis
100037941 Sus scrofa
100124505 Bos taurus
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