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Full name:
Scavenger Receptor Class B, Member 1 Proteins (SCARB1)
On www.antibodies-online.com are 15 Scavenger Receptor Class B, Member 1 (SCARB1) Proteins from 8 different suppliers available. Additionally we are shipping SCARB1 Antibodies (123) and SCARB1 Kits (20) and many more products for this protein. A total of 169 SCARB1 products are currently listed.
Synonyms:
AI120173, cb1015, CD36, Cd36l1, Cla-1, Cla1, D5Ertd460e, Hdlq1, HDLQTL6, Hlb398, mSR-BI, Scarb1, SR-B1, SR-BI, Srb1, SRBI
list all proteins Gene Name GeneID UniProt
SCARB1 949 Q8WTV0
SCARB1 20778 Q61009
SCARB1 25073 P97943

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SCARB1 Proteins (SCARB1) by Origin

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Top referenced SCARB1 Proteins

  1. Human SCARB1 Protein expressed in HEK-293 Cells - ABIN2181726 : Scarselli, Ansuini, Cerino, Roccasecca, Acali, Filocamo, Traboni, Nicosia, Cortese, Vitelli: The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. in The EMBO journal 2002 (PubMed)

More Proteins for SCARB1 Interaction Partners

Human Scavenger Receptor Class B, Member 1 (SCARB1) interaction partners

  1. Model recombinant HDL (show HSD11B1 Proteins) (rHDL) particles formed in vitro with S1P (show MBTPS1 Proteins) incorporated into the particle initiated the internalization of S1PR1 (show S1PR1 Proteins), whereas rHDL without supplemented S1P (show MBTPS1 Proteins) did not, suggesting that S1P (show MBTPS1 Proteins) transported in HDL (show HSD11B1 Proteins) can selectively activate S1PR1 (show S1PR1 Proteins).

  2. Data implicate that scavenger receptor class B member 1 (SR-B1) as a target in chronic lymphocytic leukemia (CLL) and high-density lipoproteins nanoparticles (HDL (show HSD11B1 Proteins) NPs (show NPS Proteins)) as targeted monotherapy for CLL.

  3. SCARB1 gene polymorphisms may contribute to genetic susceptibility to coronary heart disease. C allele of rs10846744 and the C allele of rs2278986 may serve as risk and protective factors for CHD (show CHDH Proteins), respectively.

  4. VEGF-A (show VEGFA Proteins) was found to be a prerequisite for the localization of scavenger receptor BI in the plasma membrane of endothelial cells and is a regulatory factor of transendothelial transport of HDL (show HSD11B1 Proteins) but not LDL.

  5. our findings implied that scavenger receptor class B type 1 might serve as a diagnostic and independent prognostic biomarker in clear cell renal cell carcinoma (show MOK Proteins).

  6. data support an SR-B1 nibbling mechanism that is similar to that of streptococcal serum opacity factor, which also selectively removes CE and releases apoAI, leaving an apoAII (show APOA2 Proteins)-rich remnant.

  7. Using mass spectrometry and site directed mutagenesis, a new Sp1 (show PSG1 Proteins) phosphorylation site Ser702 was defined to be associated with Sp1 (show PSG1 Proteins)-HDAC1 (show HDAC1 Proteins) interaction and may be important in SR-BI activation, shedding light on the knowledge of delicate mechanism of hepatic HDL (show HSD11B1 Proteins) receptor SR-BI gene modulation by LDL.

  8. down-regulation of SR-BI by endoplasmic reticulum stress in hepatic cells might contribute to the unfavorable effects of metabolic disorders on cholesterol homeostasis and cardiovascular diseases

  9. We confirmed associations with papillary thyroid cancer and SNPs in FOXE1 (show FOXE1 Proteins)/HEMGN, SERPINA5 (show SERPINA5 Proteins) (rs2069974), FTO (show FTO Proteins) (rs8047395), EVPL (rs2071194), TICAM1 (show TICAM1 Proteins) (rs8120) and SCARB1 (rs11057820) genes. We found associations with SNPs in FOXE1 (show FOXE1 Proteins), SERPINA5 (show SERPINA5 Proteins), FTO (show FTO Proteins), TICAM1 (show TICAM1 Proteins) and HSPA6 (show HSPA6 Proteins) and and follicular thyroid cancer

  10. The data from this ex vivo study suggests that up-regulated SR-B1 protein expression is associated with malignant behaviors of breast cancer and that SR-B1 is an independent predictor for poor survival in breast cancer patients.

Mouse (Murine) Scavenger Receptor Class B, Member 1 (SCARB1) interaction partners

  1. Our results suggest that LPA-enhanced foam cell formation is mediated by LPA1 (show LPAR1 Proteins)/3 -AKT (show AKT1 Proteins) activation and subsequent SRBI expression.

  2. Results show the first high-resolution structure of the C-terminal transmembrane domain of SR-BI. This region of SR-BI harbors a leucine zipper dimerization motif, which when mutated impairs the ability of the receptor to bind HDL (show HSD11B1 Proteins) and mediate cholesterol delivery.

  3. Results show the first high-resolution structure of the C-terminal transmembrane domain of SR-BI. This region of SR-BI harbors a leucine zipper dimerization motif, which when mutated impairs the ability of the receptor to bind HDL (show HSD11B1 Proteins) and mediate cholesterol delivery.

  4. Carboxy-terminal deletion of SR-BI reduced receptor levels in liver and steroidogenic tissues (adrenal cortex, ovary, testicular Leydig cells) and induced hypercholesterolemia.

  5. Loss of ScarB1 is associated with Coronary Atherosclerosis and Ischemic Heart Disease in Low-density Lipoprotein Receptor (show LDLR Proteins) Knockout Mice when fed the modified western-type diet.

  6. We showed here that SR-BI deficiency led to increased atherogenesis with features of advanced fibroatheroma and expansive arterial remodeling in LDL-R KO mice fed an atherogenic diet.

  7. The seven intron CGIs are methylated differentially in Y1 cells, mouse Leydig tumor cells, ovarian granulosa cells, and mouse liver hepa 1-6 cells; experiments raised the possibility that DNA methylation (show HELLS Proteins) participates in hormonal regulation of SR-BI expression in a tissue-specific manner.

  8. SR-B1, the HDL (show HSD11B1 Proteins) receptor, is expressed abundantly in liver sinusoidal endothelial cells and marginally in hepatocytes.

  9. SR-B1 and targeted HDL (show HSD11B1 Proteins) NPs (show NPS Proteins) provide a fundamental advance in studying cholesterol-dependent cellular uptake mechanisms.

  10. Studied the role of SR-BI in endothelial cells using several novel transgenic mouse models expressing SR-BI in endothelium of mice with normal C57Bl6/N, apoE (show APOE Proteins)-KO, or Scarb1-KO backgrounds.

Pig (Porcine) Scavenger Receptor Class B, Member 1 (SCARB1) interaction partners

  1. Luteinization causes upregulation of SR-BI expression, its posttranslational maturation by glycosylation, and insertion into luteal cell membranes.

Cow (Bovine) Scavenger Receptor Class B, Member 1 (SCARB1) interaction partners

  1. Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI or ABCG1 (show ABCG1 Proteins) but not ABCA1 (show ABCA1 Proteins).

SCARB1 Protein Profile

Protein Summary

The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SCARB1

  • scavenger receptor class B, member 1 (scarb1)
  • scavenger receptor class B, member 1 (SCARB1)
  • scavenger receptor class B, member 1 (Scarb1)
  • scavenger receptor class B member 1 (CpipJ_CPIJ014332)
  • scavenger receptor class B member 1 (CpipJ_CPIJ019101)
  • AI120173 protein
  • cb1015 protein
  • CD36 protein
  • Cd36l1 protein
  • Cla-1 protein
  • Cla1 protein
  • D5Ertd460e protein
  • Hdlq1 protein
  • HDLQTL6 protein
  • Hlb398 protein
  • mSR-BI protein
  • Scarb1 protein
  • SR-B1 protein
  • SR-BI protein
  • Srb1 protein
  • SRBI protein

Protein level used designations for SCARB1

scavenger receptor class B member 1 , scavenger receptor class B, member 1 , scavenger receptor class B type I , high density lipoprotein receptor SR-BI , CD36 and LIMPII analogous 1 , CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1 , scavenger receptor class B type III , HDL QTL 1 , scavenger receptor class B1 , CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1) , SR-BI , scavanger receptor class B type 1 , SRB1 , CD36 antigen (collagen type I receptor, thrombospondin receptor-like 1)

GENE ID SPECIES
387260 Danio rerio
452359 Pan troglodytes
486241 Canis lupus familiaris
100009590 Oryctolagus cuniculus
100322870 Cavia porcellus
6047494 Culex quinquefasciatus
6053185 Culex quinquefasciatus
949 Homo sapiens
20778 Mus musculus
25073 Rattus norvegicus
416814 Gallus gallus
397018 Sus scrofa
282346 Bos taurus
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