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anti-Human VLDLR Antibodies:
anti-Mouse (Murine) VLDLR Antibodies:
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Cow (Bovine) Monoclonal VLDLR Primary Antibody for ICC, IF - ABIN4365609
Roberts, Barnard, Liang, Vaziri: Effect of diet on adipose tissue and skeletal muscle VLDL receptor and LPL: implications for obesity and hyperlipidemia. in Atherosclerosis 2002
Show all 5 Pubmed References
Human Polyclonal VLDLR Primary Antibody for FACS, IF (p) - ABIN705551
Fredriksson, Mishra, Lam, Mushaben, Cuento, Meyer, Yao, Keeran, Nugent, Qu, Yu, Yang, Raghavachari, Dagur, McCoy, Levine: The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses. in Journal of immunology (Baltimore, Md. : 1950) 2014
In the second family, we identified a previously unreported homozygous missense change, c.154T > C (p.Cys52Arg) in the VLDLR gene
VLDLR expression was negatively regulated by miR (show MLXIP Antibodies)-200c Colorectal cancer (CRC (show CALR Antibodies)) cells and their expression levels were inversely correlated in CRC (show CALR Antibodies) patients.
We screened for mutations in RELN (show RELN Antibodies) or VLDLR and compared the phenotype of these patients with that of previously reported patients. differences in clinical severity, involvement of the cerebellar hemispheres, together with the severity of the neocortical defect, enables RELN (show RELN Antibodies)-mutated patients to be distinguished from VLDLR-mutated patients.
Data suggest that, in the binding of fibrin beta N-domains and the (1-8) peptide fragment of VLDLR (very low density lipoprotein receptor), the second and third Lys (show LYZ Antibodies)/Arg clusters in fibrin make major contributions to this interaction while the contribution of the first cluster is moderate.
The presence of reelin (show RELN Antibodies) was elevated in junctional areas as in dysplastic nevi. VLDLR presented positive values in 16 cases (16/ 32) and ApoER2 (show LRP8 Antibodies) was weak positive in 7 cases.
These results for the first time demonstrated that SalA protected against IS/RP-induced endothelial barrier dysfunction through suppression of VLDL receptor expression
these results suggest that VLDLR functions in vivo as an HCV receptor independent of canonical CD81 (show CD81 Antibodies)-mediated HCV entry.
the results obtained indicate that minimal fibrin-binding structures are located within the second and third CR domains of the VLDL receptor and the presence of the fourth CR domain is required for high-affinity binding
The results of this study demonstrated the presence of reelin (show RELN Antibodies), its receptors VLDLR and ApoER2 (show LRP8 Antibodies) as well as Dab1 (show DAB1 Antibodies) in the ENS and might indicate a novel role of the reelin (show RELN Antibodies) system in regulating neuronal plasticity and pre-synaptic functions in the ENS.
these results suggested that the miR (show MLXIP Antibodies)-135a-VLDLR-p38 (show CRK Antibodies) axis may contribute to gallbladder cancer cell proliferation
C-terminal truncation of the reelin (show RELN Antibodies) protein disrupts the interaction of reelin (show RELN Antibodies) with VLDLR, resulting in abnormal development of the cerebral cortex and hippocampus.
Study showed that the two major VLDLR splice variants have differential activities in regulating Wnt (show WNT2 Antibodies) signaling due to their different ectodomain shedding rates, which identified the functional difference of these splice variants.
The absence of PCSK9 (show PCSK9 Antibodies) results in a sex- and tissue-specific subcellular distribution of the LDLR (show LDLR Antibodies) and VLDLR, which is determined by estradiol levels.
In the retinas of Vldlr(-/-) mice with low fatty acid uptake but high circulating lipid levels, we found that Ffar1 (show FFAR1 Antibodies) suppresses expression of the glucose transporter Glut1 (show SLC2A1 Antibodies)
neuronal stress differentially regulates lipoprotein receptor expression in neurons, with VLDLR upregulation as a common element as a modulator of neuronal Wnt (show WNT2 Antibodies) signaling
Subretinal vascularization (SRV) in the Vldlr-/- model is associated with mistargeted neurites and that SRV is preceded by altered retinal vascular development.
VLDLR requires RasGRF1 (show RASGRF1 Antibodies)/CaMKII (show CAMK2G Antibodies) to alter dendritic spine formation.
This study demonstrated that VLDLR is expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex.
LRP5 (show LRP5 Antibodies) signaling is a prerequisite for neovascularization in VLDLR knockout mice. LRP5 (show LRP5 Antibodies) may be an effective target for inhibiting intraretinal neovascularization.
these results identify a novel role for the VLDLR as a negative regulator of DC-mediated adaptive immune responses in HDM (show HDAC3 Antibodies)-induced allergic airway inflammation.
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
, very low-density lipoprotein receptor
, VTG receptor
, very low density lipoprotein (VLDL)/vitellogenin receptor
, vitellogenin receptor