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Human Polyclonal DNAJC1 Primary Antibody for WB - ABIN2783864
Kroczynska, King-Simmons, Alloza, Alava, Elguindi, Blond: BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4. in Biochemical and biophysical research communications 2005
ITIH4 (show ITIH4 Antibodies) and MTJ1 co-immunoprecipitate from total liver protein extracts and SANT domain of HTJ1 protects the ITIH4 (show ITIH4 Antibodies)(588-930) recombinant fragment
Data suggest that vaspin (show SERPINA12 Antibodies) is a ligand for cell-surface GRP78 (show HSPA5 Antibodies) (glucose-regulated protein (show HSP90B1 Antibodies) 78kD)/MTJ-1 complex; subsequent signal transduction exerts beneficial effects on endoplasmic reticulum stress-induced metabolic dysfunctions as seen in obesity.
In addition to assisting the chaperone GRP78 (show HSPA5 Antibodies) in protein quality control in the endoplasmic reticulum, MTJ-1 is essential for transport of GRP78 (show HSPA5 Antibodies) to the macrophage surface, which serves a number of functions in immune regulation and signal transduction.
ERj1p coordinates the ribosome at the membrane and allosteric effects may mediate ERj1p's regulatory activity
ERj1p inhibits translation in the absence of BiP (show HSPA5 Antibodies), and mediates binding of the nuclear import factor importin beta (show KPNB1 Antibodies) and import into the nucleus.
plasma membrane-associated GRP78 (show HSPA5 Antibodies) is coupled to pertussis toxin-insensitive Galphaq11 and forms a ternary signaling complex with MTJ-1
May modulate protein synthesis (By similarity).
DnaJ (Hsp40) homolog, subfamily C, member 1
, dnaJ homolog subfamily C member 1
, DnaJ-like protein
, dnaJ protein homolog MTJ1
, DnaJ-like protein 1