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Browse our DNAJC2 Proteins (DNAJC2)

Full name:
DnaJ (Hsp40) Homolog, Subfamily C, Member 2 Proteins (DNAJC2)
On www.antibodies-online.com are 9 DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) Proteins from 4 different suppliers available. Additionally we are shipping DNAJC2 Antibodies (39) and many more products for this protein. A total of 51 DNAJC2 products are currently listed.
Synonyms:
AU020218, MIDA1, MPHOSPH11, MPP11, zgc:85671, Zrf1, Zrf2, ZUO1
list all proteins Gene Name GeneID UniProt
DNAJC2 27000 Q99543
DNAJC2 22791 P54103
Rat DNAJC2 DNAJC2 116456 Q7TQ20

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DNAJC2 Proteins (DNAJC2) by Origin

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More Proteins for DNAJC2 Interaction Partners

Human DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) interaction partners

  1. ZRF1 mediates remodeling of this E3 ligase complex directly at the DNA lesion site.

  2. The antibody response to ZRF1 was higher in sera of patients with invasive ductal carcinoma than in sera of patients with other histological types of breast tumors.

  3. Zrf1 is transcriptional regulator of neural fate downstream of Id1 (show ID1 Proteins) in embryonic stem cells.During embryonic stem cell differentiation, Id1 (show ID1 Proteins) levels decrease allowing Zrf1 to activate neural genes.

  4. our data reveal that ZRF1 is a key transcriptional regulator in leukemia progression

  5. Zrf1 plays an essential role in neural progenitor cell generation and maintenance

  6. ZRF1 regulates the INK4-ARF locus during cellular proliferation and senescence, and alterations in ZRF1 may contribute to tumorigenesis.

  7. the majority of AML (show RUNX1 Proteins) patients elicited a humoral immune response against the tumor antigen MPP11 (show PMPCB Proteins)

  8. describe a novel epitope derived from the MPP11 (show PMPCB Proteins) antigen that has been recognized by human CD8 (show CD8A Proteins)+ CTL

  9. At the onset of differentiation, ZRF1 specifically displaces polycomb (show CBX2 Proteins)-repressive complex 1 (PRC1 (show PRC1 Proteins)) from chromatin and facilitates transcriptional activation

  10. concluded that Mpp11 (show PMPCB Proteins), an ortholog of yeast Zuo, is a ribosome-associated J protein; proposed that in metazoans, ribosome-associated Zuo and Mpp11 (show PMPCB Proteins) orthologs recruit cytosolic Hsc70 (show HSPA8 Proteins) to short ribosome-bound nascent chains as they exit the ribosome

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2) interaction partners

  1. Data suggest involvement of MIDA1 in the stimulation of transcription in concert with Hsp70/Hsc70 molecular chaperones.

DNAJC2 Protein Profile

Protein Summary

This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

Alternative names and synonyms associated with DNAJC2

  • DnaJ (Hsp40) homolog, subfamily C, member 2 (dnajc2)
  • DnaJ (Hsp40) homolog, subfamily C, member 2 (DNAJC2)
  • DnaJ (Hsp40) homolog, subfamily C, member 2 (Dnajc2)
  • AU020218 protein
  • MIDA1 protein
  • MPHOSPH11 protein
  • MPP11 protein
  • zgc:85671 protein
  • Zrf1 protein
  • Zrf2 protein
  • ZUO1 protein

Protein level used designations for DNAJC2

dnaJ homolog subfamily C member 2 , zuotin related factor 1 , M-phase phosphoprotein 11 , zuotin-related factor 1 , Id associate 1 , zuotin related factor 2 , (rat homolog) mouse id-associated protein 1 , gliosarcoma-related antigen MIDA1

GENE ID SPECIES
394933 Xenopus (Silurana) tropicalis
417717 Gallus gallus
27000 Homo sapiens
22791 Mus musculus
116456 Rattus norvegicus
507897 Bos taurus
403080 Danio rerio
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