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Browse our K(lysine) Acetyltransferase 2A Proteins (KAT2A)

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K(lysine) Acetyltransferase 2A Proteins (KAT2A)
On www.antibodies-online.com are 12 K(lysine) Acetyltransferase 2A (KAT2A) Proteins from 6 different suppliers available. Additionally we are shipping K(lysine) Acetyltransferase 2A Antibodies (105) and many more products for this protein. A total of 125 K(lysine) Acetyltransferase 2A products are currently listed.
Synonyms:
1110051E14Rik, AW212720, Gcn5, Gcn5l2, hGCN5, KAT2A, mmGCN5, PCAF-b
list all proteins Gene Name GeneID UniProt
KAT2A 2648 Q92830
KAT2A 14534 Q9JHD2
Rat KAT2A KAT2A 303539  

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K(lysine) Acetyltransferase 2A Proteins (KAT2A) by Origin

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Top referenced K(lysine) Acetyltransferase 2A Proteins

  1. Human KAT2A Protein expressed in Escherichia coli (E. coli) - ABIN667533 : Col, Caron, Seigneurin-Berny, Gracia, Favier, Khochbin: The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for ABIN667533

More Proteins for K(lysine) Acetyltransferase 2A Interaction Partners

Human K(lysine) Acetyltransferase 2A (KAT2A) interaction partners

  1. Data suggest that expression of GCN5 (histone acetyltransferase GCN5) is induced in skeletal muscle during a 48-hour fast; in contrast, expression of SIRT1 (sirtuin 1 (show SIRT1 Proteins)) remains unchanged.

  2. Orc5 (show ORC5 Proteins) associates with the H3 histone (show HIST1H3B Proteins) acetyl transferase (show HAT1 Proteins) GCN5 (also known as KAT2A), and this association enhances the chromatin-opening function of Orc5 (show ORC5 Proteins).

  3. Methionine was the only essential amino acid that rapidly induced PGC-1alpha acetylation through activating the GCN5 acetyltransferase.

  4. these results may point to the GCN5-NF-kappaB (show NFKB1 Proteins) pathway as a novel potential molecular target for stem cell mediated regenerative medicine and the treatment of metabolic bone diseases such as osteoporosis.

  5. Acetyltransferase p300 (show EP300 Proteins) collaborates with chromodomain helicase DNA-binding protein 4 (CHD4 (show CHD4 Proteins)) to facilitate DNA double-strand break repair

  6. Suggest lysine acetyltransfer as a potential regulator of platelet actin dynamics, and potential roles for lysine acetylation in the molecular coordination of platelet activation and function.

  7. Data uncover GCN5 as a negative regulator of C/EBPalpha (show CEBPA Proteins) and demonstrate the importance of C/EBPalpha (show CEBPA Proteins) acetylation in myeloid differentiation.

  8. GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 (show STAT3 Proteins) and AKT (show AKT1 Proteins) Signaling Pathways

  9. results thus demonstrate that the catalytic activity of GCN5 is stimulated by subunits of the ADA2a (show TADA2A Proteins)- or ADA2b (show TADA2B Proteins)-containing HAT (show MGEA5 Proteins) modules and is further increased by incorporation of the distinct HAT (show MGEA5 Proteins) modules in the ATAC (show XCL1 Proteins) or SAGA holo-complexes

  10. GCN5 plays a positive role in human colon cancer development, and its suppression holds a great therapeutic potential in antitumor therapy

Mouse (Murine) K(lysine) Acetyltransferase 2A (KAT2A) interaction partners

  1. Methionine was the only essential amino acid that rapidly induced PGC-1alpha acetylation through activating the GCN5 acetyltransferase.

  2. these results may point to the GCN5-NF-kappaB (show NFKB1 Proteins) pathway as a novel potential molecular target for stem cell mediated regenerative medicine and the treatment of metabolic bone diseases such as osteoporosis.

  3. In addition to reducing atrogene expression, surprisingly inhibiting NF-kappaB (show NFKB1 Proteins) with IkappaBalpha (show NFKBIA Proteins)-SR or by GCN5 knockdown in these muscles also enhanced AKT (show AKT1 Proteins) and mechanistic target of rapamycin (mTOR (show FRAP1 Proteins)) activities, which also contributed to the reduction in atrophy.

  4. Gcn5 and PCAF (show KAT2B Proteins) repress IFN-beta (show IFNB1 Proteins) production in an enzymatic activity-independent and non-transcriptional manner: by inhibiting the innate immune signaling kinase TBK1 (show TBK1 Proteins) in the cytoplasm.

  5. GCN5 and HDAC1 (show HDAC1 Proteins) are the crucial enzymes that regulating epigenetic reprogramming; we observed dynamic changes in the expression levels of GCN5 and HDAC1 (show HDAC1 Proteins) during embryo development

  6. In conclusion, these data establish Kat2a as a novel and essential regulator of hippocampal memory consolidation.

  7. Study reveals that Gcn5/PCAF (show KAT2B Proteins) facilitate adipogenesis through regulation of PPARgamma (show PPARG Proteins) expression and regulate brown adipogenesis by influencing Prdm16 (show PRDM16 Proteins) expression.

  8. Sirt6 interacts with and modifies GCN5, enhancing GCN5's activity.

  9. Data support a model in which p23 and GCN5 regulate diverse multistep pathways by controlling the longevity of protein-DNA complexes.

  10. Data have defined an important role for GCN5 in NSC and provided evidence that GCN5 is an important Myc (show MYC Proteins) transcriptional cofactor in vivo.

K(lysine) Acetyltransferase 2A (KAT2A) Protein Profile

Protein Summary

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009

Alternative names and synonyms associated with K(lysine) Acetyltransferase 2A (KAT2A)

  • K(lysine) acetyltransferase 2A (KAT2A)
  • K(lysine) acetyltransferase 2A (kat2a)
  • K(lysine) acetyltransferase 2A (Kat2a)
  • 1110051E14Rik protein
  • AW212720 protein
  • Gcn5 protein
  • Gcn5l2 protein
  • hGCN5 protein
  • KAT2A protein
  • mmGCN5 protein
  • PCAF-b protein

Protein level used designations for KAT2A

histone acetyltransferase KAT2A , general control of amino acid synthesis 5-like 2 , GCN5 general control of amino-acid synthesis 5-like 2 , general control of amino acid synthesis protein 5-like 2 , K(lysine) acetyltransferase 2A , GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 , General control of amino acid synthesis, yeast, homolog-like 2 , STAF97 , histone acetyltransferase GCN5 , hsGCN5 , lysine acetyltransferase 2A , GCN5 general control of amino acid synthesis-like 2 , PCAF-B/GCN5 , general control of amino acid synthesis, yeast homolog-like 2 , general control of amino acid synthesis-like 2

GENE ID SPECIES
552646 Apis mellifera
374232 Gallus gallus
454677 Pan troglodytes
490971 Canis lupus familiaris
100176452 Ciona intestinalis
100597293 Nomascus leucogenys
2648 Homo sapiens
14534 Mus musculus
303539 Rattus norvegicus
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