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Browse our anti-Lysyl Oxidase-Like 2 (LOXL2) Antibodies

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anti-Lysyl Oxidase-Like 2 Antibodies (LOXL2)
On are 104 Lysyl Oxidase-Like 2 (LOXL2) Antibodies from 19 different suppliers available. Additionally we are shipping Lysyl Oxidase-Like 2 Proteins (28) and Lysyl Oxidase-Like 2 Kits (24) and many more products for this protein. A total of 162 Lysyl Oxidase-Like 2 products are currently listed.
1110004B06Rik, 4930526G11Rik, 9430067E15Rik, CG4402, Dmel\\CG4402, dmlox-2, Dmloxl-2, GB13360, LOR2, lox2-like, loxl-2, LOXL2, WS9-14
list all antibodies Gene Name GeneID UniProt
LOXL2 4017 Q9Y4K0
LOXL2 94352 P58022
LOXL2 290350 B5DF27

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Top referenced anti-Lysyl Oxidase-Like 2 Antibodies

  1. Human Monoclonal LOXL2 Primary Antibody for ELISA, WB - ABIN396576 : Rodriguez, Vaysberg, Mikels, McCauley, Velayo, Garcia, Smith: Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN396576

  2. Human Polyclonal LOXL2 Primary Antibody for EIA, WB - ABIN953202 : Rückert, Joensson, Saeger, Grützmann, Pilarsky: Functional analysis of LOXL2 in pancreatic carcinoma. in International journal of colorectal disease 2010 (PubMed)
    Show all 4 references for ABIN953202

  3. Human Monoclonal LOXL2 Primary Antibody for ELISA, WB - ABIN561690 : Fujimoto, Tajima: Reciprocal regulation of LOX and LOXL2 expression during cell adhesion and terminal differentiation in epidermal keratinocytes. in Journal of dermatological science 2009 (PubMed)
    Show all 3 references for ABIN561690

  4. Human Polyclonal LOXL2 Primary Antibody for ICC, IF - ABIN442901 : Wong, Zhang, Gilkes, Chen, Wei, Chaturvedi, Hubbi, Semenza: Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis. in Journal of molecular medicine (Berlin, Germany) 2012 (PubMed)

  5. Human Polyclonal LOXL2 Primary Antibody for ELISA, WB - ABIN561689 : Ghiggeri, Gigante, Di Donato et al.: Constitutional Nephrin Deficiency in Conditionally Immortalized Human Podocytes Induced Epithelial-Mesenchymal Transition, Supported by β-Catenin/NF-kappa B Activation: A Consequence of Cell Junction ... in International journal of nephrology 2014 (PubMed)

More Antibodies against Lysyl Oxidase-Like 2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Lysyl Oxidase-Like 2 (LOXL2) interaction partners

  1. Dmloxl-1 and Dmloxl-2 are differentially expressed; active DmLOXL-1 influences gene expression and development

Human Lysyl Oxidase-Like 2 (LOXL2) interaction partners

  1. The expression levels of lysyl oxidase-like 2 (LOXL2) mRNA and protein were markedly suppressed in transfected prostate cancer cells with microRNAs miR (show MLXIP Antibodies)-26a, miR (show MLXIP Antibodies)-26b, miR (show MLXIP Antibodies)-29a, miR (show MLXIP Antibodies)-29b, miR (show MLXIP Antibodies)-29c and miR (show MLXIP Antibodies)-218.

  2. Overexpression of LOXL2 and SERPINH1 (show SERPINH1 Antibodies) was observed in clinical specimens of lung cancer and fibrotic lesions. Downregulation of miR (show MLXIP Antibodies)-29a caused overexpression of LOXL2 and SERPINH1 (show SERPINH1 Antibodies) in lung cancer and IPF, suggesting that these genes are involved in the pathogenesis of these two diseases.

  3. LOXL2 expression is significantly upregulated in human masticatory mucosa during wound healing

  4. BMP2 (show BMP2 Antibodies) and RUNX2 (show RUNX2 Antibodies) are expressed exclusively by osteoblasts whereas DSPP (show DSPP Antibodies) and LOXL2 are expressed exclusively by odontoblasts. (Review)

  5. Results showed that LOXL2 was overexpressed in head and neck squamous cell carcinoma clinical specimens and that silencing of the LOXL2 gene significantly inhibited the migration and invasion of cancer cells.

  6. ECM (show MMRN1 Antibodies) crosslinking by EC-derived exosomes is mediated by LOXL2.

  7. Results show that miR (show MLXIP Antibodies)-26a and miR (show MLXIP Antibodies)-26b were significantly downregulated in renal cell carcinoma (show MOK Antibodies) clinical specimens and appeared to function as tumor suppressors through regulation of collagen cross-linking enzymes, LOXL2 and PLOD2 (show PLOD2 Antibodies), both of which function as oncogenes in this disease.

  8. Loss of tumor-suppressive miR29s enhanced cancer cell invasion in lung SCC (show CYP11A1 Antibodies) through direct regulation of oncogenic LOXL2.

  9. LOXL2 promotes tumor progression.

  10. We identified LOXL2 to be associated with the outcome of colon cancer patients. Furthermore, it can be used to stratify patients at stages II and III for further therapeutic decisions.

Mouse (Murine) Lysyl Oxidase-Like 2 (LOXL2) interaction partners

  1. LOX (show LOX Antibodies) and LOXL2 (show LOXL3 Antibodies) may play an important role in the pathogenesis of AMD (show AMD1 Antibodies). Targeting LOXL2 (show LOXL3 Antibodies) could have a broader efficacy than targeting LOX (show LOX Antibodies), by reducing angiogenesis and inflammation, as well as fibrosis.

  2. Loss and gain of function analyses combined with in vivo studies in syngeneic breast cancer models demonstrate the participation of LOXL2 (show LOXL3 Antibodies) and E47 (show TCF3 Antibodies) in tumor growth and their requirement for lung metastasis.

  3. Findings reveal new insight into the mechanisms of fibroblast activation, a novel function of LOXL2 (show LOXL3 Antibodies), and further highlight the importance of generating LOXL2 (show LOXL3 Antibodies)-targeted therapies for the prevention of tumor progression and metastasis.

  4. The Snail1 (show SNAI1 Antibodies) transcription factor represses mouse pericentromeric transcription, acting through the H3K4 deaminase LOXL2 (show LOXL3 Antibodies).

  5. The enzymatic activity of lysyl oxidas-like-2 (LOXL2 (show LOXL3 Antibodies)) is not required for LOXL2 (show LOXL3 Antibodies)-induced inhibition of keratinocyte differentiation.

  6. This study provides the first evidence for the role of LOXL2 (show LOXL3 Antibodies) in regulating angiogenesis through collagen IV (show COL4 Antibodies) scaffolding.

  7. LOXL2 (show LOXL3 Antibodies) promotes chondrocyte differentiation by mechanisms that are likely to include roles as both a regulator and an effector of chondrocyte differentiation

  8. The efficacy and safety of LOXL2 (show LOXL3 Antibodies)-specific monoclonal antibody represents a new therapeutic approach with broad applicability in oncologic and fibrotic diseases.

  9. LoxL2 (show LOXL3 Antibodies) is not expressed in MC3T3-E1 cells.

Lysyl Oxidase-Like 2 (LOXL2) Antigen Profile

Antigen Summary

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Alternative names and synonyms associated with Lysyl Oxidase-Like 2 (LOXL2)

  • lysyl oxidase-like 2 (lox2) antibody
  • lysyl oxidase-like 2 (LOXL2) antibody
  • lysyl oxidase-like 2 (loxl2) antibody
  • lysyl oxidase-like 2 (Loxl2) antibody
  • 1110004B06Rik antibody
  • 4930526G11Rik antibody
  • 9430067E15Rik antibody
  • CG4402 antibody
  • Dmel\\CG4402 antibody
  • dmlox-2 antibody
  • Dmloxl-2 antibody
  • GB13360 antibody
  • LOR2 antibody
  • lox2-like antibody
  • loxl-2 antibody
  • LOXL2 antibody
  • WS9-14 antibody

Protein level used designations for LOXL2

CG4402-PA , lox2-PA , lysyl oxidase-like 2 , Lysyl oxidase-like protein 2 , lysyl oxidase homolog 2 , lysyl oxidase homolog 2-like , lysyl oxidase related 2 , lysyl oxidase-like protein 2 , lysyl oxidase-related protein 2 , lysyl oxidase-related protein WS9-14 , Lysyl oxidase homolog 2

37485 Drosophila melanogaster
408544 Apis mellifera
585092 Strongylocentrotus purpuratus
100158339 Xenopus laevis
100216062 Xenopus (Silurana) tropicalis
100413360 Callithrix jacchus
464053 Pan troglodytes
710151 Macaca mulatta
100543026 Meleagris gallopavo
4017 Homo sapiens
419533 Gallus gallus
486118 Canis lupus familiaris
532684 Bos taurus
94352 Mus musculus
290350 Rattus norvegicus
100171427 Pongo abelii
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