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Browse our anti-SF3B1 (SF3B1) Antibodies

Full name:
anti-Splicing Factor 3b, Subunit 1, 155kDa Antibodies (SF3B1)
On www.antibodies-online.com are 66 Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Antibodies from 14 different suppliers available. Additionally we are shipping SF3B1 Proteins (3) and SF3B1 Kits (1) and many more products for this protein. A total of 78 SF3B1 products are currently listed.
Synonyms:
155kDa, 2810001M05Rik, AA409119, Hsh155, MDS, PRP10, PRPF10, sap155, SF3B1, SF3b155, TA-8, Targ4, wu:fb99f09
list all antibodies Gene Name GeneID UniProt
SF3B1 81898  
SF3B1 84486  
SF3B1 23451 O75533

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anti-Mouse (Murine) SF3B1 Antibodies:

anti-Rat (Rattus) SF3B1 Antibodies:

anti-Human SF3B1 Antibodies:

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Top referenced anti-SF3B1 Antibodies

  1. Human Polyclonal SF3B1 Primary Antibody for IHC (p), WB - ABIN657676 : Corsini, Hothorn, Stier, Rybin, Scheffzek, Gibson, Sattler: Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60. in The Journal of biological chemistry 2008 (PubMed)
    Show all 3 references for ABIN657676

  2. Cow (Bovine) Polyclonal SF3B1 Primary Antibody for IHC, WB - ABIN2778699 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

  3. Hamster Monoclonal SF3B1 Primary Antibody for WB - ABIN1449178 : Horie, Isono, Koseki: Generation of a monoclonal antibody against the mouse Sf3b1 (SAP155) gene product for U2 snRNP component of spliceosome. in Hybridoma and hybridomics 2003 (PubMed)

  4. Cow (Bovine) Polyclonal SF3B1 Primary Antibody for WB - ABIN2779035 : Avila, Bercovich, Westergaard, Levin, Vázquez: Mapping of the protein-binding interface between splicing factors SF3b155 and p14 of Trypanosoma cruzi. in Biochemical and biophysical research communications 2007 (PubMed)

  5. Cow (Bovine) Polyclonal SF3B1 Primary Antibody for IHC, WB - ABIN2778700 : Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)

More Antibodies against SF3B1 Interaction Partners

Zebrafish Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. Data indicate that splicing factor 3b (show SF3B14 Antibodies), subunit 1 (sf3b1) mutation causes aberrant splicing of sf3b1 resulting in functional and predicted non-functional transcripts and a 90% reduction in full-length Sf3b1 protein.

Mouse (Murine) Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. myocardial hypoxia actuates fructose metabolism in human and mouse models of pathological cardiac hypertrophy through hypoxia-inducible factor 1alpha (HIF1alpha (show HIF1A Antibodies)) activation of SF3B1 and SF3B1-mediated splice switching of KHK (show KHK Antibodies)-A to KHK (show KHK Antibodies)-C

  2. Sf3b1 isrequired for the blastocyst formation.

  3. SF3B1 plays an important role in the regulation of hematopoietic stem cells, whereas SF3B1 haploinsufficiency itself is not associated with the myelodysplastic syndrome phenotype with ring sideroblasts.

  4. The level of Sf3b1 expression is critical for the proliferative capacity of hematopoietic stem cells. Depletion of Sf3b1 impairs proliferative capacity of hematopoietic stem cells but is not sufficient to induce myelodysplasia.

  5. SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes.

  6. the active spliceosome, containing SAP155 phosphorylated by DYRKIA, performs pre-mRNA splicing in spermatogonia during testicular development

  7. active spliceosome, containing phosphorylated SAP155, performs pre-mRNA splicing on chromatin concomitant with transcription during testicular development.

  8. Sf3b1 and Polycomb (show CBX2 Antibodies) group (PcG) proteins interaction is essential for true PcG-mediated repression of Hox (show MSH2 Antibodies) genes.

Human Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. recent insights into the molecular mechanisms of mis (show AMH Antibodies)-splicing caused by mutant SF3B1 (show SF3B2 Antibodies) and the pathogenesis of RSs (show GRB10 Antibodies) in the context of congenital sideroblastic anemia as well as anemia with ringed sideroblasts with SF3B1 (show SF3B2 Antibodies) mutations.

  2. Patients with uveal melanoma can be classified into 3 groups, of which EIF1AX (show EIF1AX Antibodies)-mutated tumors and tumors without BAP1 (show RNF2 Antibodies), SF3B1 (show SF3B2 Antibodies), or EIF1AX (show EIF1AX Antibodies) mutations are associated with prolonged survival and low metastatic risk, SF3B1 (show SF3B2 Antibodies)-mutated tumors are associated with late metastasis

  3. Results show that SF3B1 (show SF3B2 Antibodies) mutation was found to dysregulate multiple cellular functions in CLL including DNA damage response, telomere maintenance, and Notch (show NOTCH1 Antibodies) signaling through splicing alterations.

  4. BAP1 (show RNF2 Antibodies), SF3B1 (show SF3B2 Antibodies), and EIF1AX (show EIF1AX Antibodies) mutations occur during uveal melanoma tumor progression in an almost mutually exclusive manner and are associated with different levels of metastatic risk.

  5. Mutations in ASXL1 (show ASXL1 Antibodies), U2AF1 (show U2AF1 Antibodies), and SF3B1 (show SF3B2 Antibodies) are common in Chinese patients with myelodysplastic syndromes.

  6. The clinical impact of small subclones harboring NOTCH1 (show NOTCH1 Antibodies), SF3B1 (show SF3B2 Antibodies), or BIRC3 (show BIRC3 Antibodies) mutations in chronic lymphocytic leukemia patients appears to be less pronounced than that of small TP53 (show TP53 Antibodies) mutated subclones.

  7. No relationship was observed between IGHV mutational status and SF3B1 (show SF3B2 Antibodies) mutationfa

  8. The genotype frequencies of SF3B1 (show SF3B2 Antibodies) SNP rs788018 were TT 13.2%, TC 39.6%, and CC 47.2% in Childhood AML (show RUNX1 Antibodies) patients.

  9. The finding of this study showed that an SF3B1 (show SF3B2 Antibodies) or EIF1AX (show EIF1AX Antibodies) mutation is present in a substantial subset of primary LMNs underscores that these tumors genetically resemble uveal melanoma and are different from cutaneous melanoma at the genetic level.

  10. SF3B1 (show SF3B2 Antibodies)-mutated myelodysplastic syndrome with ring sideroblasts harbors more severe iron overload and corresponding over-erythropoiesis.

SF3B1 Antigen Profile

Antigen Summary

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with SF3B1

  • splicing factor 3b, subunit 1, 155kDa (SF3B1) antibody
  • splicing factor 3b, subunit 1, 155kDa (sf3b1) antibody
  • splicing factor 3b, subunit 1 (sf3b1) antibody
  • splicing factor 3b, subunit 1 (Sf3b1) antibody
  • 155kDa antibody
  • 2810001M05Rik antibody
  • AA409119 antibody
  • Hsh155 antibody
  • MDS antibody
  • PRP10 antibody
  • PRPF10 antibody
  • sap155 antibody
  • SF3B1 antibody
  • SF3b155 antibody
  • TA-8 antibody
  • Targ4 antibody
  • wu:fb99f09 antibody

Protein level used designations for SF3B1

splicing factor 3b, subunit 1, 155kDa , splicing factor 3B subunit 1 , splicing factor 3B subunit 1-like , tst , SAP 155 , pre-mRNA-splicing factor SF3b 155 kDa subunit , spliceosome-associated protein 155 , splicing factor 3b, subunit 1, 155 kDa , transforming growth factor alpha regulated gene 4 , splicing factor 3b, subunit 1, 155kD , 146 kDa nuclear protein , SF3b155 , pre-mRNA processing 10 , pre-mRNA splicing factor SF3b, 155 kDa subunit

GENE ID SPECIES
459850 Pan troglodytes
510177 Bos taurus
697773 Macaca mulatta
100022236 Monodelphis domestica
100070506 Equus caballus
100413687 Callithrix jacchus
100477819 Ailuropoda melanoleuca
100547422 Meleagris gallopavo
100559157 Anolis carolinensis
100604147 Nomascus leucogenys
446117 Danio rerio
81898 Mus musculus
84486 Rattus norvegicus
399336 Xenopus laevis
424056 Gallus gallus
23451 Homo sapiens
488456 Canis lupus familiaris
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